Munich Study for Beer Related ECG Change Workup (Munich BREW)
研究概览
详细说明
Both regular and acute excessive alcohol intake may deteriorate health. Possible sequelae include cardiac arrhythmias. For acute alcohol intake in particular it is insufficiently understood to what extent cardiac arrhythmias and other ECG changes occur, if the occurence depends on alcohol levels, and if there is a cut off value for occurence. Munich BREW aims to help clarifying these questions.
Participants of Munich BREW are identified and invited as visitors of the Munich Octoberfest and similar events. Participants need to be 18 years of age and over and need to declare theri will to participate. Following enrollment, participants will answer astudy questionnaire and will subsequently undergo recording of a 30 sec smart phone based ECG. Ultimately, the alcohol level is determined using a breath alcohol analyzer.
研究类型
注册 (预期的)
联系人和位置
学习地点
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Munich、德国、81377
- Klinikum der Universitaet Muenchen, Department of Medicine I
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- 18 years of age and older
- informed conset signature
Exclusion Criteria:
- Incapability of contracting according to German law (BGB §105, paragraph 2)
- contraindications against ECG recording or alcohol breath test
- denial of informed consent
学习计划
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
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Acute alcohol intake
Visitors of the Munich Octoberfest or similar events who fulfil in- and exclusion criteria
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Smart phone based ECG recording
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研究衡量的是什么？
主要结果指标
结果测量 |
大体时间 |
|---|---|
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Occurence of cardiac arrhythmias
大体时间：30 sec
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30 sec
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次要结果测量
结果测量 |
大体时间 |
|---|---|
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Alcohol related changes in ECG intervals
大体时间：30 sec
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30 sec
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合作者和调查者
赞助
调查人员
- 首席研究员：Stefan Brunner, MD、LMU Klinikum
出版物和有用的链接
一般刊物
- Brunner S, Drobesch C, Herbel R, Sinner MF. Effects of acute alcohol consumption on cardiac excitation, conduction, and repolarization: results from the Munich Beer Related Electrocardiogram Workup Study (MunichBREW). Clin Res Cardiol. 2021 Jun;110(6):916-918. doi: 10.1007/s00392-021-01839-6. Epub 2021 Mar 18. No abstract available.
- Brunner S, Herbel R, Drobesch C, Peters A, Massberg S, Kaab S, Sinner MF. Alcohol consumption, sinus tachycardia, and cardiac arrhythmias at the Munich Octoberfest: results from the Munich Beer Related Electrocardiogram Workup Study (MunichBREW). Eur Heart J. 2017 Jul 14;38(27):2100-2106. doi: 10.1093/eurheartj/ehx156.
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (估计)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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