Retrospective Longitudinal Study of Gestational Weight Gain Among Chinese Pregnant Women (GWGCPW)
2017年5月11日 更新者：Jing Tan、West China Hospital
The purpose of this study is to investigate the reference ranges and rates of gestational weight gain among Chinese pregnant women, and to analyze the correlation between gestational weight gain and adverse outcomes.
研究概览
地位
完全的
条件
研究类型
观察性的
注册 (实际的)
10422
参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 孩子
- 成人
- 年长者
接受健康志愿者
不
有资格学习的性别
女性
取样方法
非概率样本
研究人群
Chinese pregnant women who had deliveries at West China Women and Children's Hospital, Sichuan University
描述
Inclusion Criteria:
- Deliveries between January 2013 and December 2014;
- Gestational age between 37 weeks or older and less than 42 weeks;
- Registration with care documents at the first prenatal visit prior to the 15th gestational week;
- Had at least five follow-up visits until delivery.
Exclusion Criteria: None
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Preeclampsia
大体时间：After 20th gestational weeks till delivery, about 5 months
|
Maternal systolic pressure ≥140 mmHg and/or diastolic pressure ≥90 mmHg during gestation.
Urine protein ≥5.0 g within 24h, urine volume <400 mL.
HELLP syndrome or pulmonary edema present.
|
After 20th gestational weeks till delivery, about 5 months
|
|
Eclampsia
大体时间：After 20th gestational weeks till delivery, about 5 months
|
Tonic-clonic seizures (convulsions) in preeclampsia patients, including convulsions and coma, not due to pre-existing or organic brain disorders.
|
After 20th gestational weeks till delivery, about 5 months
|
|
ICP
大体时间：After 14th gestational weeks till delivery, about 6 months
|
Intrahepatic cholestasis of pregnancy.
|
After 14th gestational weeks till delivery, about 6 months
|
|
Placenta previa
大体时间：During pregnancy till delivery
|
Placenta partially or entirely covered the lower uterine segment diagnosed using antenatal ultrasound.
|
During pregnancy till delivery
|
|
Gestational diabetes
大体时间：After 24th gestational weeks, about 4 months
|
By oral glucose tolerance test between 24th and 28th gestational weeks (fasting glucose ≥5.1 mmol/L, 1-h glucose ≥10.0 mmol/L, 2-h glucose ≥8.5 mmol/L; one abnormal result sufficient).
|
After 24th gestational weeks, about 4 months
|
|
Ruptured uterus
大体时间：During delivery
|
Rupture of maternal uterus confirmed by laparotomy.
|
During delivery
|
|
Placental abruption
大体时间：After 20th gestational weeks till delivery, about 5 months
|
Abruption of a normally positioned placenta before delivery, diagnosed by clinical symptoms, ultrasound, fetal heart monitoring, or laboratory tests.
|
After 20th gestational weeks till delivery, about 5 months
|
|
Postpartum hemorrhage
大体时间：Within 24h after delivery
|
Postpartum bleeding volume ≥500 mL.
|
Within 24h after delivery
|
|
Hepatic diseases
大体时间：During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
Hepatitis-B/C/E virus infection, acute fatty liver disease, or severe hepatitis.
|
During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
|
Hematological diseases
大体时间：During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
Iron-deficiency anemia, thalassemia, hemophilia, idiopathic thrombocytopenic purpura, aplastic anemia, or disseminated intravascular coagulation.
|
During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
|
Gynecological diseases
大体时间：During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
Uterine fibroids, ovarian cyst, cervical carcinoma, pelvic inflammation, or ovarian carcinoma.
|
During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
|
Respiratory diseases
大体时间：During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
Pneumonia, bronchitis, asthma or pulmonary tuberculosis.
|
During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
|
Thyroid disease
大体时间：During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
Hyperthyroidism or hypothyroidism.
|
During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
|
ICU admission
大体时间：During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
Admission to intensive care unit.
|
During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
|
Maternal death
大体时间：During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
Maternal death.
|
During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
|
Macrosomia
大体时间：within 1 month after delivery
|
Birth weight >4000 g.
|
within 1 month after delivery
|
|
Infant of low-birth weight
大体时间：within 1 month after delivery
|
Birth weight <2500 g.
|
within 1 month after delivery
|
|
Neonatal ICU admission
大体时间：Within 1 month after delivery
|
Admission to neonatal intensive care unit.
|
Within 1 month after delivery
|
|
Neonatal death
大体时间：Within 1 month after delivery
|
Neonatal death.
|
Within 1 month after delivery
|
|
Large for gestational age
大体时间：Within 1 month after delivery
|
Neonatal weight, length, or head circumference above the 90th percentile for that gestational age.
|
Within 1 month after delivery
|
|
Small for gestational age
大体时间：Within 1 month after delivery
|
Neonatal weight, length, or head circumference below the 10th percentile for that gestational age.
|
Within 1 month after delivery
|
|
Neonatal defect
大体时间：Within 1 month after delivery
|
Neonatal defect.
|
Within 1 month after delivery
|
|
Maternal adverse outcomes
大体时间：During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
There occurred one or more of preeclampsia, eclampsia, ICP, placenta previa, gestational diabetes, ruptured uterus, placental abruption, postpartum hemorrhage, hepatic diseases, hematological diseases, gynecological diseases, respiratory diseases, thyroid disease, ICU admission, or maternal death.
|
During pregnancy, delivery or within 42 days of pregnancy termination, an average of 1 year
|
|
Neonatal adverse outcomes
大体时间：Within 1 month after delivery
|
There occurred one or more of macrosomia, low-birth weight, neonatal ICU admission, neonatal death, large for gestational age, small for gestational age, or neonatal defect.
|
Within 1 month after delivery
|
合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员：Xin Sun, Doctor、Chinese Evidence-based Medicine Center, West China Hospital, Sichuan University
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2015年1月1日
初级完成 (实际的)
2016年12月1日
研究完成 (实际的)
2017年3月1日
研究注册日期
首次提交
2017年3月24日
首先提交符合 QC 标准的
2017年5月11日
首次发布 (实际的)
2017年5月16日
研究记录更新
最后更新发布 (实际的)
2017年5月16日
上次提交的符合 QC 标准的更新
2017年5月11日
最后验证
2017年5月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.