Physiological Behavior of Respiratory Maneuvers
Physiological Behavior of Respiratory Maneuvers Through Electrical Impedance Tomography and Optoelectronic Plethymography
Introduction: new methods of evaluation of respiratory function, such as electrical impedance tomography (EIT) and optoelectronic plethysmography (OEP), have been used to measure regional pulmonary ventilation and the variation of tricompartmental volumes of the thoracic cavity, respectively. Analysis of these instruments during maximal respiratory maneuvers with monitoring of esophageal pressure may probably provide additional information on the physiological behavior of the cardiorespiratory system during EIT and OEP maneuvers. Objectives: To describe the physiological behavior of maximal respiratory maneuvers through the electrical impedance tomography and optoelectronic plethysmography in healthy men.
METHODS: This is a cross-sectional study involving 10 healthy male volunteers. The development of the method will take place in 3 stages. The first step corresponds to the characterization of the inspiratory and expiratory curves in the respiratory cycle generated by the impedance variation (ΔZ), the mobility of the chest wall and the pulmonary volume curve during maximal respiratory maneuvers. 2nd stage: verification of the correlation between the variables Step 3: Estimate the dislocated blood volume of the lung through previous analyzes.
研究概览
地位
条件
详细说明
研究类型
注册 (实际的)
联系人和位置
学习地点
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PE - Pernambuco
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Recife、PE - Pernambuco、巴西、50740300
- Universidade Federal de Pernambuco
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
- Will be included in the study male volunteers,
- BMI greater than or equal to 18.5 and less than 25 kg / m2, considered adequate or eutrophic (MS, 2011)
- Chest circumference between 44 and 55 cm if fitted to the electrical impedance tomography (EIT) strap size P or M;
- systolic blood pressure lower than 140 mmHg and greater than 100 mmHg
- diastolic blood pressure greater than 60 mmHg and lower than 90 mmHg (VI Brazilian Guidelines for Hypertension, 2010)
- without reports of cardiovascular or pulmonary diseases and symptoms Last month.
Exclusion Criteria:
- Volunteers who refuse to participate in the study will be excluded from the survey;
- Presence of cardiac dysfunction assessed by echocardiography;
- Altered pulmonary function by spirometry (PEREIRA et al, 2001) and manovacuometry according to predicted values for healthy individuals (PESSOA et al, 2014).
- Presence of tissue injury in the thorax;
- Dysautonomia that may indicate dysfunction of the autonomic nervous system (ANS), with following clinical manifestations: seizures; epilepsy; Anhydrosis and hyperhidrosis; Neurogenic bladder (CASTRO et al, 1992); (Stewart et al., 2004 and 2005)
- individuals who donated blood or had significant blood loss within 30 days prior to the start of the study (Navarro et al, 1997).
学习计划
研究是如何设计的？
设计细节
- 观测模型：其他
- 时间观点：横截面
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Displacement of blood volume of the lung
大体时间：09/03/2018
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Volume displacement per unit time measured by electrical impedance tomography through the impedance variation in Ohm (Ω).
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09/03/2018
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Variation of pulmonary electrical impedance
大体时间：09/03/2018
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Variation between the final and initial impedance measured by electrical impedance tomography through the impedance variation in Ohm (Ω).
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09/03/2018
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其他结果措施
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Lung volume
大体时间：09/03/2018
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Measurement of the amount of air that the lungs may contain at various points in the respiratory cycle.
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09/03/2018
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合作者和调查者
调查人员
- 首席研究员：Cláudia Thais Pinto, Ms、UFPE
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他研究编号
- 23031990
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
药物和器械信息、研究文件
研究美国 FDA 监管的药品
研究美国 FDA 监管的设备产品
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