The Mindfulness Intervention as Myocardial Infarction Rehabilitation Additive (MIMIRA) Study (MIMIRA)
研究概览
详细说明
Depressive symptomatology in patients with coronary artery disease (CAD) has prognostic importance. Yet, psychological interventions in clinical practice are scarce. Here, we explored the feasibility and acceptability of mindfulness-based stress reduction (MBSR) in patients with depressive symptoms after a recent coronary event. A second aim was to investigate psychological risk factors and resources among participants.
To address the research questions, depressive symptoms were first measured in a reference population, at 1 and 12 months after a coronary event (myocardial infarction or unstable angina pectoris), and a cut-off for elevated depressive symptoms were obtained from the median in this group. Thereafter, similar CAD patients with elevated depressive symptoms (above median in the reference group), from the same outpatient clinic, were consecutively invited to an 8-week MBSR program. Serious physical or psychiatric illness that would be an obstacle to participation were exclusion criteria.
Patients who completed the MBSR-course were asked to evaluate its various facets, and completion rate and attendance were feasibility outcomes. Psychological variables were measured before, after the course as well as 12 months later.
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
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-
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Linköping、瑞典、581 83
- Linköping University
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Recent (within 12 month) first time coronary artery event; defined as a diagnosis of myocardial infarction or unstable angina pectoris addressed with either percutaneous coronary intervention (PCI) or coronary artery by-pass graft surgery (CABG).
- Depressive symptoms above a score of 8 on the questionnaire centre for epidemiological studies depression scale (CES-D).
- Interest for participation in MBSR.
Exclusion Criteria:
- Major depression or other serious psychiatric illness (such as psychosis or ongoing life crisis).
- Severe comorbidities, such as cancer, severe cognitive impairment and alcohol or drug abuse.
- Practical hindrances for participation in MBSR.
学习计划
研究是如何设计的？
设计细节
- 主要用途：支持治疗
- 分配：不适用
- 介入模型：单组作业
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：MBSR participation
Participation in the 8 week Mindfulness Based Stress Reduction (MBSR) course.
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An 8-week course in mindfulness meditation, yoga training and weekly group support in the form of weekly 2,5 hour meetings at the hospital.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Feasibility
大体时间：Immediately after the 8-week intervention.
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Patient evaluation questionnaire
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Immediately after the 8-week intervention.
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Depressive Symptoms
大体时间：Before, immediately after and 12 months post intervention.
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Centre for Epidemiological Studies Scale Depression (CES-D) questionnaire (Radloff)
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Before, immediately after and 12 months post intervention.
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Anxiety
大体时间：Before, immediately after and 12 months post intervention.
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Generalized Anxiety Disorder Scale - 7 (GAD-7) questionnaire (Spitzer)
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Before, immediately after and 12 months post intervention.
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Mindfulness
大体时间：Before, immediately after and 12 months post intervention.
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Five Facets of Mindfulness Questionnaire (FFMQ) (Baer)
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Before, immediately after and 12 months post intervention.
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Acceptance
大体时间：Before, immediately after and 12 months post intervention.
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Acceptance and Action Questionnaire II (AAQII) (Block)
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Before, immediately after and 12 months post intervention.
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Mastery
大体时间：Before, immediately after and 12 months post intervention.
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Mastery questionnaire (Pearlin & Shooler)
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Before, immediately after and 12 months post intervention.
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Self-esteem
大体时间：Before, immediately after and 12 months post intervention.
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Self-esteem questionnaire (Rosenberg)
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Before, immediately after and 12 months post intervention.
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Patients experiences of mindfulness training
大体时间：Continuously during the 8 week course.
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Written journal entries (linguistic content)
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Continuously during the 8 week course.
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合作者和调查者
调查人员
- 首席研究员：Lena LJ Jonasson, M.D. Ph.D.、Division of Cardiovascular Medicine, Department of Medical and Health Sciences, Linköping University
出版物和有用的链接
一般刊物
- Lundgren O, Garvin P, Nilsson L, Tornerefelt V, Andersson G, Kristenson M, Jonasson L. Mindfulness-Based Stress Reduction for Coronary Artery Disease Patients: Potential Improvements in Mastery and Depressive Symptoms. J Clin Psychol Med Settings. 2022 Sep;29(3):489-497. doi: 10.1007/s10880-021-09822-z. Epub 2021 Sep 28.
- Lundgren O, Garvin P, Kristenson M, Jonasson L, Thylen I. A journey through chaos and calmness: experiences of mindfulness training in patients with depressive symptoms after a recent coronary event - a qualitative diary content analysis. BMC Psychol. 2018 Sep 13;6(1):46. doi: 10.1186/s40359-018-0252-1.
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
与本研究相关的术语
其他研究编号
- 2013/17/31
计划个人参与者数据 (IPD)
计划共享个人参与者数据 (IPD)？
IPD 计划说明
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