MDD(Mild Cognitive Impairment Delirium Dementia) Cohort
2022年7月28日 更新者：Kyoung ja Moon、Keimyung University Dongsan Medical Center
A Prospective, Longitudinal Cohort Study of the Incidence of Dementia After the Onset of Delirium in Patients With Mild Cognitive Impairment: MDD Cohort (Mild Cognitive Impairment Delirium Dementia)
- Identify the degree of delirium in subjects with mild cognitive impairment and find the risk factors of delirium. Mortality, hospital stay, and medical expenses are analyzed as clinical consequences related to delirium incidence.
- Dementia conversion rate and conversion period of subjects with mild cognitive impairment with delirium and it identifies the effect of delirium on dementia conversion.
- Develop an AI(Artificial intelligence) algorithm for predicting dementia transition in subjects with mild cognitive impairment based on the research results of the 1st, 2nd, and 3rd years.
研究概览
研究类型
观察性的
注册 (预期的)
163
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习联系方式
- 姓名：Kyoung ja Moon, doctor
- 电话号码：+821023026302
- 邮箱：kjmoon2150@gmail.com
研究联系人备份
- 姓名：min a Park
- 电话号码：+821023026302
- 邮箱：kjmoon2150@gmail.com
学习地点
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Gyeongsangnam-do,
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Daegu、Gyeongsangnam-do,、大韩民国、50572
- 招聘中
- Yangsan Seoul long-term care (LTC) facilities
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接触：
- YooJeong Yang
- 电话号码：821054258230
- 邮箱：hp79797@naver.com
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Jeollabuk-do
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Daegu、Jeollabuk-do、大韩民国、54078
- 尚未招聘
- Gunsan Chamsarang long-term care (LTC) facilities
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接触：
- Hyeonsuk An
- 电话号码：+821020788428
- 邮箱：rkdxogns76@naver.com
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参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
65年 及以上 (年长者)
接受健康志愿者
不
有资格学习的性别
全部
取样方法
概率样本
研究人群
Patients admitted to 3 long-term care (LTC) facilities
描述
Inclusion Criteria:
- Patients 65 years of age or older who are admitted to a LTC
- Patients diagnosed with mild cognitive impairment by doctors
- Patients with a score of 18 or more and 23 or less on the Mini-Mental State Examination
Exclusion Criteria:
- Patients unable to measure the delirium assessment tool, The Short Confusion Assessment Methods (S-CAM) (Inouye, 2014) due to severe vision and hearing problems
- Patients with serious psychiatric or neurological diagnosis,Patients who expire or were transferred on the day of admission -
- Patients receiving emergency treatment at the time of the delirium assessment or unable to measure or intervene with S-CAM due to hospital circumstances
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
干预/治疗 |
|---|---|
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MCI(Mild Cognitive Impairment) group
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Twice a day, the rounds of nurses in shifts, 8:00 am - 10:00 am, 4:00 pm - 6:00 pm Trained research assistants assessed delirium using S-CAM
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Delirium incidence in participants with mild cognitive impairment
大体时间：The number of subjects evaluated as positive in the delirium assessment using S-CAM for 30 days from the 1st day of study participation is statistically calculated.
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descriptive statistics
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The number of subjects evaluated as positive in the delirium assessment using S-CAM for 30 days from the 1st day of study participation is statistically calculated.
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Dementia conversion rate and transition period in participants with mild cognitive impairment
大体时间：The participant's dementia conversion is checked in units of 1 month, and the period until conversion to dementia is analyzed in units of 12 months for 36 months.
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descriptive statistics
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The participant's dementia conversion is checked in units of 1 month, and the period until conversion to dementia is analyzed in units of 12 months for 36 months.
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Risk factors affecting participants' delirium
大体时间：On the first day of data collection, the characteristics of subjects are collected through medical records. After 12 months, the risk factors affecting the occurrence of delirium among the characteristics of the subject are analyzed.
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Logistic Regression
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On the first day of data collection, the characteristics of subjects are collected through medical records. After 12 months, the risk factors affecting the occurrence of delirium among the characteristics of the subject are analyzed.
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Mortality
大体时间：It is statistically calculated in 30-day, 60-day, 12-month, 24-month, and 36-month increments.
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Kaplan-Meier survival, Cox proportional hazard regression, Logistic Regression
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It is statistically calculated in 30-day, 60-day, 12-month, 24-month, and 36-month increments.
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hospital length of stay
大体时间：The period from hospitalization to discharge is calculated in days and analyzed in units of 12 months.
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Linear Regression
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The period from hospitalization to discharge is calculated in days and analyzed in units of 12 months.
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healthcare costs
大体时间：From the healthcare costs consumed during the hospital length of stay, the direct healthcare costs used only for treatment are calculated in won units and analyzed in units of 12 months.
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Linear Regression
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From the healthcare costs consumed during the hospital length of stay, the direct healthcare costs used only for treatment are calculated in won units and analyzed in units of 12 months.
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2021年7月1日
初级完成 (预期的)
2022年10月31日
研究完成 (预期的)
2025年12月31日
研究注册日期
首次提交
2021年10月17日
首先提交符合 QC 标准的
2021年10月28日
首次发布 (实际的)
2021年11月9日
研究记录更新
最后更新发布 (实际的)
2022年8月1日
上次提交的符合 QC 标准的更新
2022年7月28日
最后验证
2022年7月1日
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.