Influence of Wet Clothing on Thermal Protection
研究概览
地位
条件
详细说明
Participants, in their first visit, will undergo baseline weighted treadmill walking consisting of ~20 min of treadmill walking with a load of 77lbs followed by ~25 min of treadmill walking with a load of 38.5lbs. They will also have their body composition evaluated (DEXA) and be fit for each uniform ensemble. This first laboratory visit will require ~3 hrs.
On separate days, participants will complete 4 experimental trials. After being submerged up to the neck in warm water for two minutes, three of the trials will ask that the participant move to a 41°F air environment, stand with minimal movement for 60 min, complete 60 min of weighted (38.5lb) treadmill walking at 2 mph, and up to 4% grade, and then complete 60 min of weighted (38.5lb) treadmill walking at 2.5 mph and up to 4% grade. Each of these three experimental trial visits will require ~5 hrs.
A single trial will ask that after being saturated in warm water, participants enter a 41°F air environment, immediately begin weighted treadmill walking (38.5lbs) at 2.0mph and up to 4% grade for a duration of 60 min before standing with minimal movement for 60 min. This trial will require ~4 hrs.
During all experimental trials, the primary outcomes include core temperature, measured continuously using a small pill inserted as a rectal suppository, and skin temperature, measured continuously using 11 small skin attached sensors. Secondary outcomes include metabolic rate, heart rate, thermal perceptions, and changes in body mass.
Non-federally employed civilians may be eligible to be paid $13.50/hour for participation (for a total of up to $310).
研究类型
注册 (预期的)
阶段
- 不适用
联系人和位置
学习联系方式
- 姓名：Afton D Seeley, Ph.D.
- 电话号码：508-206-2423
- 邮箱：afton.d.seeley.civ@health.mil
学习地点
-
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Massachusetts
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Natick、Massachusetts、美国、01760
- 招聘中
- USARIEM
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接触：
- Afton D Seeley, Ph.D.
- 电话号码：508-206-2423
- 邮箱：afton.d.seeley.civ@health.mil
-
-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Military or civilian, male or female, between the ages of 18 (17 if active duty military) and 49 years.
- Able to carry a rucksack weighing 35 kg (77lbs) for at least 20 minutes and able to carry a rucksack weighing 17.5kg (38.5lbs) for up to 120 minutes
- In good health as determined by our OMSO (Office of Medical Support and Oversight) General Medical Clearance.
- Vaccinated against COVID 19.
- Willing to refrain from heavy exercise and alcoholic beverages for 24 hours before each testing session.
- Willing to refrain from smoking or tobacco use for 8 hours before each testing session.
- Willing to refrain from caffeine ingestion for 12 hours before each testing session.
- Body fat percentage <18% for males, < 24% for females, once 6 individuals of higher body fat (18% or greater for males, 24% or greater for females) have completed the study.
Exclusion Criteria:
- History of cold injuries.
- Raynaud's syndrome.
- Cold-induced asthma/bronchospasm.
- Medications or dietary supplements that could alter cardiovascular, thermoregulatory, or vascular control.
- Heart, lung, kidney, muscle, or nerve disorder(s).
- Planned MRI during or within two days after completing the study.
- Known allergy to adhesives.
- Female and pregnant, planning to become pregnant, or breastfeeding.
学习计划
研究是如何设计的？
设计细节
- 主要用途：其他
- 分配：随机化
- 介入模型：交叉作业
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的：Improved Hot Weather Combat Uniform
Wearing the Improved Hot Weather Combat Uniform; Asked to perform 60 min of standing with minimal movement, 60 min weighted (38.5lb) treadmill walking at 2.0mph, up to 4% grade, 60 min weight (38.5lb) treadmill walking at 2.5mph, up to 4% grade.
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Water-saturated Improved Hot Weather Combat Uniform
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实验性的：Army Combat Uniform
Wearing the Army Combat Uniform; Asked to perform 60 min of standing with minimal movement, 60 min weighted (38.5lb) treadmill walking at 2.0mph, up to 4% grade, 60 min weight (38.5lb) treadmill walking at 2.5mph, up to 4% grade.
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Water-saturated Army Combat Uniform
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实验性的：Army Combat Uniform + Silk Weights
Wearing the Army Combat Uniform + a base layer of silk weights; Asked to perform 60 min of standing with minimal movement, 60 min weighted (38.5lb) treadmill walking at 2.0mph, up to 4% grade, 60 min weight (38.5lb) treadmill walking at 2.5mph, up to 4% grade.
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Water-saturated Army Combat Uniform + Silk Weights
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实验性的：Army Combat Uniform- XR
Wearing the Army Combat Uniform; Asked to perform 60 min weighted (38.5lb) treadmill walking at 2.0mph, up to 4% grade, followed by 60 min of standing with minimal movement
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Water-saturated Army Combat Uniform
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Core Temperature
大体时间：5 hours
|
Core temperature will be measured using a temperature pill that is inserted as a rectal suppository.
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5 hours
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Skin Temperature
大体时间：5个小时
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Skin temperature will be measured using 11 different skin-attached temperature sensors.
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5个小时
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Heart Rate
大体时间：5 hours
|
Heart Rate will be measured using telemetry [beats per min]
|
5 hours
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耗氧量/代谢产热 (MHP)
大体时间：多个 5 分钟收集最多 1 小时
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耗氧量和 MHP 将使用计算机间接量热法 [ml/kg/min；瓦每平方米]
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多个 5 分钟收集最多 1 小时
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Thermal Sensation (whole body, feet, and hands)
大体时间：multiple 1 minute collections up to 1 hour
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Thermal sensation will be assessed using the American Society of Heating, Refrigerating and Air-conditioning Engineers Thermal Sensation Scale.
This scale has numbers from -4 to +4 with every whole number accompanied by a verbal expression.
The verbal expressions are used only to give the subject a relative feeling pertaining to the relative sensation.
For example, -4 is associated with very cold whereas +4 is associated with very hot.
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multiple 1 minute collections up to 1 hour
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Thermal Comfort
大体时间：multiple 1 minute collections up to 1 hour
|
Thermal comfort will be assessed using a standard Thermal Comfort Scale.
We will ask volunteers to rate how comfortable they feel with respect to temperature sensation.
The scale has numbers ranging from 0 to 4 and with descriptors ranging from comfortable (0) to intolerable (4).
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multiple 1 minute collections up to 1 hour
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Perceived Skin Wetness
大体时间：multiple 1 minute collections up to 1 hour
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Perceived Skin Wetness will be assessed using an adapted Skin Wetness Perception Scale.
The scale ranges from 0 (extremely dry) to -6 (extremely wet; soaked).
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multiple 1 minute collections up to 1 hour
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合作者和调查者
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (预期的)
研究完成 (预期的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.