Ultrasound Measurement of Skin-to-Epiglottis Distance for Prediction of Difficult Airway in Adult Patients
2026年7月16日 更新者:Almıla Gulsun Pamuk、Hacettepe University
Ultrasound Measurement of Skin to Epiglottis Distance for Prediction of Difficult Airway in Adult Patients
This prospective observational study aims to evaluate the predictive value of ultrasound-measured skin to epiglottis distance for difficult airway in adult patients undergoing elective or emergency procedures requiring airway management.
The correlation between ultrasound measurements and standard airway assessment parameters will be analyzed.
研究概览
详细说明
Airway management is a critical component of anesthesia and intensive care practice.
Predicting difficult airway remains challenging with conventional bedside tests.
Ultrasound has emerged as a non-invasive, bedside tool for airway assessment.
This study aims to investigate the relationship between skin-to-epiglottis distance measured by ultrasound and difficult laryngoscopy/intubation. Secondary comparisons will include traditional airway assessment methods such as Mallampati score, thyromental distance, and neck circumference
研究类型
观察性的
注册 (估计的)
300
联系人和位置
本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。
学习联系方式
- 姓名:Almıla G Pamuk, Doç. Dr.
- 电话号码:03123051207 9005335296325
- 邮箱:gulsunp@yahoo.com
研究联系人备份
- 姓名:muhammed r hız, research assistant
- 电话号码:9003123051207 9005417800327
- 邮箱:drrasithiz@gmail.com
学习地点
-
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Altındağ
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Ankara、Altındağ、土耳其(türkiye)、06320
- Hacettepe Univercity
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参与标准
研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
不
取样方法
概率样本
研究人群
The study population consists of adult patients scheduled for elective surgery requiring tracheal intubation under general anesthesia.
Patients will be recruited from the preoperative anesthesia clinic at [Hacettepe University Faculty of Medicine]
描述
Inclusion Criteria:
- ≥18 yaş elective surgery
Exclusion Criteria:
- emergency surgery
- head and neck surgery
- pregnant patients
学习计划
本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。
研究是如何设计的?
设计细节
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Skin to epiglottis distance
大体时间:Preintubation (within 30 minutes before procedure)
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Distance measured via ultrasound in the anterior neck region
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Preintubation (within 30 minutes before procedure)
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Incidence of difficult laryngoscopy (Cormack-Lehane grade ≥ 3)
大体时间:During intubation procedure (intraoperative period)
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The proportion of patients with difficult laryngoscopy defined as Cormack-Lehane grade 3 or 4 during direct laryngoscopy.
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During intubation procedure (intraoperative period)
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Intubation Difficulty Score (IDS)
大体时间:During intubation procedure
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Assessment of intubation difficulty using the Intubation Difficulty Score based on number of attempts, operators, alternative techniques, glottic exposure, lifting force, external laryngeal pressure, and vocal cord position.
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During intubation procedure
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Correlation between ultrasound measurements and Mallampati score
大体时间:Preoperative assessment
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Correlation between tracheal diameter and skin to epiglottis distance measured by ultrasound and preoperative Mallampati classification.
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Preoperative assessment
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Skin-to-Epiglottis Distance Measured by Ultrasound
大体时间:Immediately before induction of anesthesia
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Skin-to-epiglottis distance will be measured using ultrasound immediately before anesthesia induction.
The distance is recorded in millimeters (mm) as a continuous variable.
Larger values indicate a greater skin-to-epiglottis distance and may be associated with an increased likelihood of difficult laryngoscopy.
This is not a scored scale; therefore, no predefined minimum or maximum score exists.Cormack-Lehane Grading System.
Scores range from Grade I to Grade IV.
Grade I indicates full visualization of the glottis (easier laryngoscopy), whereas Grade IV indicates that neither the glottis nor the epiglottis is visible (most difficult laryngoscopy).
Higher grades indicate a worse airway view.
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Immediately before induction of anesthesia
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 研究主任:Almıla g Pamuk, Doç Dr.、Hacettepe Univercity
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
一般刊物
- Cook TM, Woodall N, Frerk C; Fourth National Audit Project. Major complications of airway management in the UK: results of the Fourth National Audit Project of the Royal College of Anaesthetists and the Difficult Airway Society. Part 1: anaesthesia. Br J Anaesth. 2011 May;106(5):617-31. doi: 10.1093/bja/aer058. Epub 2011 Mar 29.
- Falcetta S, Cavallo S, Gabbanelli V, Pelaia P, Sorbello M, Zdravkovic I, Donati A. Evaluation of two neck ultrasound measurements as predictors of difficult direct laryngoscopy: A prospective observational study. Eur J Anaesthesiol. 2018 Aug;35(8):605-612. doi: 10.1097/EJA.0000000000000832.
- Gani, E. (2020). Obez hastalarda zor entübasyonun öngörülmesinde ultrasonla ölçülen cilt-epiglot mesafesinin önemi (Tıpta Uzmanlık Tezi). Düzce Üniversitesi, Tıp Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Düzce.
- Uzumcugil F, Celebioglu EC, Ozkaragoz DB, Yilbas AA, Akca B, Lotfinagsh N, Celebioglu B. Body Surface Area Is Not a Reliable Predictor of Tracheal Tube Size in Children. Clin Exp Otorhinolaryngol. 2018 Dec;11(4):301-308. doi: 10.21053/ceo.2018.00178. Epub 2018 Aug 25.
- Ahmad I, El-Boghdadly K, Iliff H, Dua G, Higgs A, Huntington M, Mir F, Nouraei SAR, O'Sullivan EP, Patel A, Rivett K, McNarry AF. Difficult Airway Society 2025 guidelines for management of unanticipated difficult tracheal intubation in adults. Br J Anaesth. 2026 Jan;136(1):283-307. doi: 10.1016/j.bja.2025.10.006. Epub 2025 Nov 7.
- Altinsoy KE, Bayhan BU. Ultrasound-Measured Skin-to-Epiglottis Distance as a Predictor of Difficult Intubation in Obese Patients: A Prospective Observational Study. J Clin Med. 2025 Mar 19;14(6):2092. doi: 10.3390/jcm14062092.
- Sayir TN, Tuncer B, Erkilic E. Evaluation of upper airway ultrasonographic measurements in predicting difficult intubation: A cross-section of the Turkish population. Open Med (Wars). 2024 Aug 21;19(1):20241013. doi: 10.1515/med-2024-1013. eCollection 2024.
- Cinar Kose EO, Tekin M, Cesur S, Cam I, Baykara ZN. Evaluation of neck ultrasound measurements as a difficult airway predictor: A prospective observational study. Medicine (Baltimore). 2024 Jul 19;103(29):e38591. doi: 10.1097/MD.0000000000038591.
- Daggupati H, Maurya I, Singh RD, Ravishankar M. Development of a scoring system for predicting difficult intubation using ultrasonography. Indian J Anaesth. 2020 Mar;64(3):187-192. doi: 10.4103/ija.IJA_702_19. Epub 2020 Mar 11.
- Sotoodehnia M, Rafiemanesh H, Mirfazaelian H, Safaie A, Baratloo A. Ultrasonography indicators for predicting difficult intubation: a systematic review and meta-analysis. BMC Emerg Med. 2021 Jul 3;21(1):76. doi: 10.1186/s12873-021-00472-w.
- Zhang W, Du L, Huang Y, Liu D, Li T, Zheng J. Artificial intelligence for difficult airway assessment: a protocol for a systematic review with meta-analysis. BMJ Open. 2025 Jun 10;15(6):e096744. doi: 10.1136/bmjopen-2024-096744.
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (估计的)
2026年7月1日
初级完成 (估计的)
2026年11月1日
研究完成 (估计的)
2026年12月4日
研究注册日期
首次提交
2026年5月20日
首先提交符合 QC 标准的
2026年5月20日
首次发布 (实际的)
2026年5月27日
研究记录更新
最后更新发布 (实际的)
2026年7月17日
上次提交的符合 QC 标准的更新
2026年7月16日
最后验证
2026年7月1日
更多信息
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