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Isometric Exercise for Delayed Onset Muscle Soreness

2026年6月13日 更新者:Onur Atakan Sekibağ、Istanbul Nisantasi University

Effects of Isometric Exercise on Recovery Following Experimentally Induced Delayed Onset Muscle Soreness: A Randomized Controlled Trial

The goal of this clinical trial is to learn whether isometric exercise can improve recovery following experimentally induced delayed onset muscle soreness (DOMS) in healthy young adults.

The main questions it aims to answer are:

  • Does isometric exercise reduce pain associated with delayed onset muscle soreness?
  • Does isometric exercise improve pressure pain threshold, knee joint range of motion, muscle strength, and recovery following delayed onset muscle soreness?

Researchers will compare participants performing an isometric exercise program with a control group receiving no intervention to determine whether isometric exercise improves recovery after experimentally induced DOMS.

Participants will:

  • Undergo a standardized exercise protocol to induce delayed onset muscle soreness.
  • Be randomly assigned to either an isometric exercise group or a control group.
  • Complete assessments of pain intensity, pressure pain threshold, knee range of motion, muscle strength, and thigh circumference.
  • Be evaluated before exercise, immediately after exercise, and on Days 1, 3, and 5 following DOMS induction.

研究概览

详细说明

Delayed onset muscle soreness (DOMS) is a common consequence of unaccustomed or high-intensity physical activity, particularly exercises involving eccentric muscle contractions. DOMS is characterized by pain, tenderness, temporary reductions in muscle function, decreased range of motion, and impaired physical performance, typically peaking between 24 and 72 hours after exercise.

Various recovery strategies have been investigated to reduce the symptoms of DOMS; however, evidence regarding the effectiveness of isometric exercise in facilitating recovery remains limited. Previous studies have suggested that isometric muscle contractions may induce analgesic effects and increase pressure pain thresholds in musculoskeletal conditions. Whether these effects can improve recovery following exercise-induced muscle damage and DOMS has not been fully established.

The purpose of this randomized controlled trial was to investigate the effects of an isometric exercise program on recovery following experimentally induced DOMS in healthy adults. DOMS was induced using a standardized drop-jump protocol. Participants were randomly assigned to either an isometric exercise group or a control group. Outcome assessments were performed before DOMS induction, immediately after exercise, and during follow-up evaluations on Days 1, 3, and 5.

The findings of this study may contribute to the understanding of the role of isometric exercise as a simple, low-cost, and clinically applicable recovery strategy following exercise-induced muscle soreness.

研究类型

介入性

注册 (实际的)

40

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

  • 成人

接受健康志愿者

是的

描述

Inclusion Criteria:

  • Active athletes competing in University sports teams.
  • Age between 18 and 30 years.
  • Participation in organized sports training at least three times per week for the previous six months.
  • No lower-extremity pain at the time of enrollment.
  • Ability to safely perform the exercise protocol used to induce delayed onset muscle soreness (DOMS).
  • Willingness to provide written informed consent.

Exclusion Criteria:

  • History of lower-extremity musculoskeletal injury within the previous 6 months.
  • Previous lower-extremity surgery.
  • Current musculoskeletal pain or injury affecting sports participation.
  • Neurological, rheumatological, cardiovascular, or systemic disorders affecting physical performance.
  • Use of analgesic, anti-inflammatory, or muscle-relaxant medications during the study period.
  • Participation in strenuous eccentric exercise within 72 hours prior to baseline testing.
  • Use of recovery interventions (e.g., massage, cryotherapy, compression garments, electrical stimulation) during the study period.
  • Inability to complete the exercise protocol or follow-up assessments.

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:治疗
  • 分配:随机化
  • 介入模型:并行分配
  • 屏蔽:双倍的

武器和干预

参与者组/臂
干预/治疗
实验性的:Isometric Exercise Group
Participants in this group underwent a standardized protocol to induce delayed onset muscle soreness (DOMS) and subsequently performed a structured quadriceps isometric exercise program during the recovery period.
Participants performed a structured quadriceps isometric exercise program following experimentally induced delayed onset muscle soreness. The exercise protocol was applied according to the study protocol throughout the recovery period.
假比较器:Sham Exercise Group
Participants performed a sham exercise protocol following experimentally induced delayed onset muscle soreness. The sham intervention was designed to mimic the attention and participation associated with the experimental intervention without providing the intended therapeutic effect.
Participants performed a sham exercise protocol following experimentally induced delayed onset muscle soreness. The sham intervention was designed to mimic the attention and participation associated with the experimental intervention without providing the intended therapeutic effect.

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Pressure Pain Threshold
大体时间:Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Pressure pain threshold measured using a digital pressure algometer following experimentally induced delayed onset muscle soreness (DOMS).
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Pain Intensity
大体时间:Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Pain intensity will be assessed using the Visual Analog Scale (VAS). The VAS consists of a 10-cm horizontal line ranging from 0 (no pain) to 10 (worst imaginable pain). Participants will indicate their perceived pain intensity by marking a point on the line. Higher scores indicate greater pain intensity.
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.

次要结果测量

结果测量
措施说明
大体时间
Knee Joint Range of Motion
大体时间:Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Knee joint range of motion measured using a standard goniometer.
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Quadriceps Muscle Strength
大体时间:Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Quadriceps muscle strength measured using a handheld dynamometer.
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Thigh Circumference
大体时间:Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Thigh circumference measured using a tape measure to assess exercise-induced swelling.
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

出版物和有用的链接

负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2025年4月1日

初级完成 (实际的)

2025年7月18日

研究完成 (实际的)

2025年7月18日

研究注册日期

首次提交

2026年5月30日

首先提交符合 QC 标准的

2026年5月30日

首次发布 (实际的)

2026年6月4日

研究记录更新

最后更新发布 (实际的)

2026年6月16日

上次提交的符合 QC 标准的更新

2026年6月13日

最后验证

2026年6月1日

更多信息

与本研究相关的术语

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)?

是的

IPD 计划说明

De-identified individual participant data underlying the published results may be made available upon reasonable request to the corresponding author, subject to institutional approval and applicable ethical requirements.

IPD 共享时间框架

De-identified individual participant data, study protocol, statistical analysis plan, and analytic code will be available beginning 6 months after publication of the primary study results and ending 5 years after publication.

IPD 共享访问标准

De-identified individual participant data and supporting documents will be made available to qualified researchers upon reasonable request. Requests must include a methodologically sound research proposal and will be reviewed by the study investigators. Data will be provided after approval of the request and completion of an appropriate data-sharing agreement. Access will be limited to data necessary to achieve the approved research objectives.

IPD 共享支持信息类型

  • 研究方案
  • 树液
  • 分析代码

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

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