Isometric Exercise for Delayed Onset Muscle Soreness
30 maggio 2026 aggiornato da: Onur Atakan Sekibağ, Istanbul Nisantasi University
Effects of Isometric Exercise on Recovery Following Experimentally Induced Delayed Onset Muscle Soreness: A Randomized Controlled Trial
The goal of this clinical trial is to learn whether isometric exercise can improve recovery following experimentally induced delayed onset muscle soreness (DOMS) in healthy young adults.
The main questions it aims to answer are:
- Does isometric exercise reduce pain associated with delayed onset muscle soreness?
- Does isometric exercise improve pressure pain threshold, knee joint range of motion, muscle strength, and recovery following delayed onset muscle soreness?
Researchers will compare participants performing an isometric exercise program with a control group receiving no intervention to determine whether isometric exercise improves recovery after experimentally induced DOMS.
Participants will:
- Undergo a standardized exercise protocol to induce delayed onset muscle soreness.
- Be randomly assigned to either an isometric exercise group or a control group.
- Complete assessments of pain intensity, pressure pain threshold, knee range of motion, muscle strength, and thigh circumference.
- Be evaluated before exercise, immediately after exercise, and on Days 1, 3, and 5 following DOMS induction.
Panoramica dello studio
Stato
Completato
Intervento / Trattamento
Descrizione dettagliata
Delayed onset muscle soreness (DOMS) is a common consequence of unaccustomed or high-intensity physical activity, particularly exercises involving eccentric muscle contractions. DOMS is characterized by pain, tenderness, temporary reductions in muscle function, decreased range of motion, and impaired physical performance, typically peaking between 24 and 72 hours after exercise.
Various recovery strategies have been investigated to reduce the symptoms of DOMS; however, evidence regarding the effectiveness of isometric exercise in facilitating recovery remains limited. Previous studies have suggested that isometric muscle contractions may induce analgesic effects and increase pressure pain thresholds in musculoskeletal conditions. Whether these effects can improve recovery following exercise-induced muscle damage and DOMS has not been fully established.
The purpose of this randomized controlled trial was to investigate the effects of an isometric exercise program on recovery following experimentally induced DOMS in healthy adults. DOMS was induced using a standardized drop-jump protocol. Participants were randomly assigned to either an isometric exercise group or a control group. Outcome assessments were performed before DOMS induction, immediately after exercise, and during follow-up evaluations on Days 1, 3, and 5.
The findings of this study may contribute to the understanding of the role of isometric exercise as a simple, low-cost, and clinically applicable recovery strategy following exercise-induced muscle soreness.
Tipo di studio
Interventistico
Iscrizione (Effettivo)
40
Fase
- Non applicabile
Contatti e Sedi
Questa sezione fornisce i recapiti di coloro che conducono lo studio e informazioni su dove viene condotto lo studio.
Luoghi di studio
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Maslak
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Istanbul, Maslak, Turchia (Türkiye), 34398
- Istanbul Nisantasi University
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Criteri di partecipazione
I ricercatori cercano persone che corrispondano a una certa descrizione, chiamata criteri di ammissibilità. Alcuni esempi di questi criteri sono le condizioni generali di salute di una persona o trattamenti precedenti.
Criteri di ammissibilità
Età idonea allo studio
- Adulto
Accetta volontari sani
Sì
Descrizione
Inclusion Criteria:
- Active athletes competing in University sports teams.
- Age between 18 and 30 years.
- Participation in organized sports training at least three times per week for the previous six months.
- No lower-extremity pain at the time of enrollment.
- Ability to safely perform the exercise protocol used to induce delayed onset muscle soreness (DOMS).
- Willingness to provide written informed consent.
Exclusion Criteria:
- History of lower-extremity musculoskeletal injury within the previous 6 months.
- Previous lower-extremity surgery.
- Current musculoskeletal pain or injury affecting sports participation.
- Neurological, rheumatological, cardiovascular, or systemic disorders affecting physical performance.
- Use of analgesic, anti-inflammatory, or muscle-relaxant medications during the study period.
- Participation in strenuous eccentric exercise within 72 hours prior to baseline testing.
- Use of recovery interventions (e.g., massage, cryotherapy, compression garments, electrical stimulation) during the study period.
- Inability to complete the exercise protocol or follow-up assessments.
Piano di studio
Questa sezione fornisce i dettagli del piano di studio, compreso il modo in cui lo studio è progettato e ciò che lo studio sta misurando.
Come è strutturato lo studio?
Dettagli di progettazione
- Scopo principale: Trattamento
- Assegnazione: Randomizzato
- Modello interventistico: Assegnazione parallela
- Mascheramento: Doppio
Armi e interventi
Gruppo di partecipanti / Arm |
Intervento / Trattamento |
|---|---|
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Sperimentale: Isometric Exercise Group
Participants in this group underwent a standardized protocol to induce delayed onset muscle soreness (DOMS) and subsequently performed a structured quadriceps isometric exercise program during the recovery period.
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Participants performed a structured quadriceps isometric exercise program following experimentally induced delayed onset muscle soreness.
The exercise protocol was applied according to the study protocol throughout the recovery period.
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Comparatore fittizio: Sham Exercise Group
Participants performed a sham exercise protocol following experimentally induced delayed onset muscle soreness.
The sham intervention was designed to mimic the attention and participation associated with the experimental intervention without providing the intended therapeutic effect.
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Participants performed a sham exercise protocol following experimentally induced delayed onset muscle soreness.
The sham intervention was designed to mimic the attention and participation associated with the experimental intervention without providing the intended therapeutic effect.
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Cosa sta misurando lo studio?
Misure di risultato primarie
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
|---|---|---|
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Pressure Pain Threshold
Lasso di tempo: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Pressure pain threshold measured using a digital pressure algometer following experimentally induced delayed onset muscle soreness (DOMS).
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Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Pain Intensity
Lasso di tempo: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Pain intensity assessed using a 10-cm Visual Analog Scale (VAS) following experimentally induced delayed onset muscle soreness (DOMS).
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Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Misure di risultato secondarie
Misura del risultato |
Misura Descrizione |
Lasso di tempo |
|---|---|---|
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Knee Joint Range of Motion
Lasso di tempo: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Knee joint range of motion measured using a standard goniometer.
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Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Quadriceps Muscle Strength
Lasso di tempo: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Quadriceps muscle strength measured using a handheld dynamometer.
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Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Thigh Circumference
Lasso di tempo: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Thigh circumference measured using a tape measure to assess exercise-induced swelling.
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Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Collaboratori e investigatori
Qui è dove troverai le persone e le organizzazioni coinvolte in questo studio.
Sponsor
Pubblicazioni e link utili
La persona responsabile dell'inserimento delle informazioni sullo studio fornisce volontariamente queste pubblicazioni. Questi possono riguardare qualsiasi cosa relativa allo studio.
Pubblicazioni generali
- Rio E, Kidgell D, Purdam C, Gaida J, Moseley GL, Pearce AJ, Cook J. Isometric exercise induces analgesia and reduces inhibition in patellar tendinopathy. Br J Sports Med. 2015 Oct;49(19):1277-83. doi: 10.1136/bjsports-2014-094386. Epub 2015 May 15.
- Di Lorenzo L, Forte AM, Agosti V, Forte F, Lanciano T, Pirraglia N, D'Avanzo C. Advances in Non-Pharmacological Strategies for DOMS: A Scoping and Critical Review of Recent Evidence. J Funct Morphol Kinesiol. 2025 Nov 20;10(4):452. doi: 10.3390/jfmk10040452.
- de Morais ACL, Machado AS, Pereira MEF, da Silva W, Priego-Quesada JI, Carpes FP. Intensity and volume of physical exercise influence DOMS and skin temperature differently in healthy adults. Sci Rep. 2024 Dec 5;14(1):30282. doi: 10.1038/s41598-024-79785-2.
- Rio E, van Ark M, Docking S, Moseley GL, Kidgell D, Gaida JE, van den Akker-Scheek I, Zwerver J, Cook J. Isometric Contractions Are More Analgesic Than Isotonic Contractions for Patellar Tendon Pain: An In-Season Randomized Clinical Trial. Clin J Sport Med. 2017 May;27(3):253-259. doi: 10.1097/JSM.0000000000000364.
- Fleckenstein J, Simon P, Konig M, Vogt L, Banzer W. The pain threshold of high-threshold mechanosensitive receptors subsequent to maximal eccentric exercise is a potential marker in the prediction of DOMS associated impairment. PLoS One. 2017 Oct 6;12(10):e0185463. doi: 10.1371/journal.pone.0185463. eCollection 2017.
Studiare le date dei record
Queste date tengono traccia dell'avanzamento della registrazione dello studio e dell'invio dei risultati di sintesi a ClinicalTrials.gov. I record degli studi e i risultati riportati vengono esaminati dalla National Library of Medicine (NLM) per assicurarsi che soddisfino specifici standard di controllo della qualità prima di essere pubblicati sul sito Web pubblico.
Studia le date principali
Inizio studio (Effettivo)
1 aprile 2025
Completamento primario (Effettivo)
18 luglio 2025
Completamento dello studio (Effettivo)
18 luglio 2025
Date di iscrizione allo studio
Primo inviato
30 maggio 2026
Primo inviato che soddisfa i criteri di controllo qualità
30 maggio 2026
Primo Inserito (Effettivo)
4 giugno 2026
Aggiornamenti dei record di studio
Ultimo aggiornamento pubblicato (Effettivo)
4 giugno 2026
Ultimo aggiornamento inviato che soddisfa i criteri QC
30 maggio 2026
Ultimo verificato
1 maggio 2026
Maggiori informazioni
Termini relativi a questo studio
Parole chiave
Termini MeSH pertinenti aggiuntivi
Altri numeri di identificazione dello studio
- OASIsometricDOMS
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Criteri di accesso alla condivisione IPD
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Data will be provided after approval of the request and completion of an appropriate data-sharing agreement.
Access will be limited to data necessary to achieve the approved research objectives.
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- STUDIO_PROTOCOLLO
- LINFA
- CODICE_ANALITICO
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Studia un dispositivo regolamentato dalla FDA degli Stati Uniti
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