Isometric Exercise for Delayed Onset Muscle Soreness
30. května 2026 aktualizováno: Onur Atakan Sekibağ, Istanbul Nisantasi University
Effects of Isometric Exercise on Recovery Following Experimentally Induced Delayed Onset Muscle Soreness: A Randomized Controlled Trial
The goal of this clinical trial is to learn whether isometric exercise can improve recovery following experimentally induced delayed onset muscle soreness (DOMS) in healthy young adults.
The main questions it aims to answer are:
- Does isometric exercise reduce pain associated with delayed onset muscle soreness?
- Does isometric exercise improve pressure pain threshold, knee joint range of motion, muscle strength, and recovery following delayed onset muscle soreness?
Researchers will compare participants performing an isometric exercise program with a control group receiving no intervention to determine whether isometric exercise improves recovery after experimentally induced DOMS.
Participants will:
- Undergo a standardized exercise protocol to induce delayed onset muscle soreness.
- Be randomly assigned to either an isometric exercise group or a control group.
- Complete assessments of pain intensity, pressure pain threshold, knee range of motion, muscle strength, and thigh circumference.
- Be evaluated before exercise, immediately after exercise, and on Days 1, 3, and 5 following DOMS induction.
Přehled studie
Postavení
Dokončeno
Intervence / Léčba
Detailní popis
Delayed onset muscle soreness (DOMS) is a common consequence of unaccustomed or high-intensity physical activity, particularly exercises involving eccentric muscle contractions. DOMS is characterized by pain, tenderness, temporary reductions in muscle function, decreased range of motion, and impaired physical performance, typically peaking between 24 and 72 hours after exercise.
Various recovery strategies have been investigated to reduce the symptoms of DOMS; however, evidence regarding the effectiveness of isometric exercise in facilitating recovery remains limited. Previous studies have suggested that isometric muscle contractions may induce analgesic effects and increase pressure pain thresholds in musculoskeletal conditions. Whether these effects can improve recovery following exercise-induced muscle damage and DOMS has not been fully established.
The purpose of this randomized controlled trial was to investigate the effects of an isometric exercise program on recovery following experimentally induced DOMS in healthy adults. DOMS was induced using a standardized drop-jump protocol. Participants were randomly assigned to either an isometric exercise group or a control group. Outcome assessments were performed before DOMS induction, immediately after exercise, and during follow-up evaluations on Days 1, 3, and 5.
The findings of this study may contribute to the understanding of the role of isometric exercise as a simple, low-cost, and clinically applicable recovery strategy following exercise-induced muscle soreness.
Typ studie
Intervenční
Zápis (Aktuální)
40
Fáze
- Nelze použít
Kontakty a umístění
Tato část poskytuje kontaktní údaje pro ty, kteří studii provádějí, a informace o tom, kde se tato studie provádí.
Studijní místa
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Maslak
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Istanbul, Maslak, Turecko (Türkiye), 34398
- Istanbul Nisantasi University
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Kritéria účasti
Výzkumníci hledají lidi, kteří odpovídají určitému popisu, kterému se říká kritéria způsobilosti. Některé příklady těchto kritérií jsou celkový zdravotní stav osoby nebo předchozí léčba.
Kritéria způsobilosti
Věk způsobilý ke studiu
- Dospělý
Přijímá zdravé dobrovolníky
Ano
Popis
Inclusion Criteria:
- Active athletes competing in University sports teams.
- Age between 18 and 30 years.
- Participation in organized sports training at least three times per week for the previous six months.
- No lower-extremity pain at the time of enrollment.
- Ability to safely perform the exercise protocol used to induce delayed onset muscle soreness (DOMS).
- Willingness to provide written informed consent.
Exclusion Criteria:
- History of lower-extremity musculoskeletal injury within the previous 6 months.
- Previous lower-extremity surgery.
- Current musculoskeletal pain or injury affecting sports participation.
- Neurological, rheumatological, cardiovascular, or systemic disorders affecting physical performance.
- Use of analgesic, anti-inflammatory, or muscle-relaxant medications during the study period.
- Participation in strenuous eccentric exercise within 72 hours prior to baseline testing.
- Use of recovery interventions (e.g., massage, cryotherapy, compression garments, electrical stimulation) during the study period.
- Inability to complete the exercise protocol or follow-up assessments.
Studijní plán
Tato část poskytuje podrobnosti o studijním plánu, včetně toho, jak je studie navržena a co studie měří.
Jak je studie koncipována?
Detaily designu
- Primární účel: Léčba
- Přidělení: Randomizované
- Intervenční model: Paralelní přiřazení
- Maskování: Dvojnásobek
Zbraně a zásahy
Skupina účastníků / Arm |
Intervence / Léčba |
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Experimentální: Isometric Exercise Group
Participants in this group underwent a standardized protocol to induce delayed onset muscle soreness (DOMS) and subsequently performed a structured quadriceps isometric exercise program during the recovery period.
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Participants performed a structured quadriceps isometric exercise program following experimentally induced delayed onset muscle soreness.
The exercise protocol was applied according to the study protocol throughout the recovery period.
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Falešný srovnávač: Sham Exercise Group
Participants performed a sham exercise protocol following experimentally induced delayed onset muscle soreness.
The sham intervention was designed to mimic the attention and participation associated with the experimental intervention without providing the intended therapeutic effect.
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Participants performed a sham exercise protocol following experimentally induced delayed onset muscle soreness.
The sham intervention was designed to mimic the attention and participation associated with the experimental intervention without providing the intended therapeutic effect.
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Co je měření studie?
Primární výstupní opatření
Měření výsledku |
Popis opatření |
Časové okno |
|---|---|---|
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Pressure Pain Threshold
Časové okno: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Pressure pain threshold measured using a digital pressure algometer following experimentally induced delayed onset muscle soreness (DOMS).
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Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Pain Intensity
Časové okno: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Pain intensity assessed using a 10-cm Visual Analog Scale (VAS) following experimentally induced delayed onset muscle soreness (DOMS).
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Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Sekundární výstupní opatření
Měření výsledku |
Popis opatření |
Časové okno |
|---|---|---|
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Knee Joint Range of Motion
Časové okno: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Knee joint range of motion measured using a standard goniometer.
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Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Quadriceps Muscle Strength
Časové okno: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Quadriceps muscle strength measured using a handheld dynamometer.
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Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Thigh Circumference
Časové okno: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Thigh circumference measured using a tape measure to assess exercise-induced swelling.
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Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
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Spolupracovníci a vyšetřovatelé
Zde najdete lidi a organizace zapojené do této studie.
Sponzor
Publikace a užitečné odkazy
Osoba odpovědná za zadávání informací o studiu tyto publikace poskytuje dobrovolně. Mohou se týkat čehokoli, co souvisí se studiem.
Obecné publikace
- Rio E, Kidgell D, Purdam C, Gaida J, Moseley GL, Pearce AJ, Cook J. Isometric exercise induces analgesia and reduces inhibition in patellar tendinopathy. Br J Sports Med. 2015 Oct;49(19):1277-83. doi: 10.1136/bjsports-2014-094386. Epub 2015 May 15.
- Di Lorenzo L, Forte AM, Agosti V, Forte F, Lanciano T, Pirraglia N, D'Avanzo C. Advances in Non-Pharmacological Strategies for DOMS: A Scoping and Critical Review of Recent Evidence. J Funct Morphol Kinesiol. 2025 Nov 20;10(4):452. doi: 10.3390/jfmk10040452.
- de Morais ACL, Machado AS, Pereira MEF, da Silva W, Priego-Quesada JI, Carpes FP. Intensity and volume of physical exercise influence DOMS and skin temperature differently in healthy adults. Sci Rep. 2024 Dec 5;14(1):30282. doi: 10.1038/s41598-024-79785-2.
- Rio E, van Ark M, Docking S, Moseley GL, Kidgell D, Gaida JE, van den Akker-Scheek I, Zwerver J, Cook J. Isometric Contractions Are More Analgesic Than Isotonic Contractions for Patellar Tendon Pain: An In-Season Randomized Clinical Trial. Clin J Sport Med. 2017 May;27(3):253-259. doi: 10.1097/JSM.0000000000000364.
- Fleckenstein J, Simon P, Konig M, Vogt L, Banzer W. The pain threshold of high-threshold mechanosensitive receptors subsequent to maximal eccentric exercise is a potential marker in the prediction of DOMS associated impairment. PLoS One. 2017 Oct 6;12(10):e0185463. doi: 10.1371/journal.pone.0185463. eCollection 2017.
Termíny studijních záznamů
Tato data sledují průběh záznamů studie a předkládání souhrnných výsledků na ClinicalTrials.gov. Záznamy ze studií a hlášené výsledky jsou před zveřejněním na veřejné webové stránce přezkoumány Národní lékařskou knihovnou (NLM), aby se ujistily, že splňují specifické standardy kontroly kvality.
Hlavní termíny studia
Začátek studia (Aktuální)
1. dubna 2025
Primární dokončení (Aktuální)
18. července 2025
Dokončení studie (Aktuální)
18. července 2025
Termíny zápisu do studia
První předloženo
30. května 2026
První předloženo, které splnilo kritéria kontroly kvality
30. května 2026
První zveřejněno (Aktuální)
4. června 2026
Aktualizace studijních záznamů
Poslední zveřejněná aktualizace (Aktuální)
4. června 2026
Odeslaná poslední aktualizace, která splnila kritéria kontroly kvality
30. května 2026
Naposledy ověřeno
1. května 2026
Více informací
Termíny související s touto studií
Klíčová slova
Další relevantní podmínky MeSH
Další identifikační čísla studie
- OASIsometricDOMS
Plán pro data jednotlivých účastníků (IPD)
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Popis plánu IPD
De-identified individual participant data underlying the published results may be made available upon reasonable request to the corresponding author, subject to institutional approval and applicable ethical requirements.
Časový rámec sdílení IPD
De-identified individual participant data, study protocol, statistical analysis plan, and analytic code will be available beginning 6 months after publication of the primary study results and ending 5 years after publication.
Kritéria přístupu pro sdílení IPD
De-identified individual participant data and supporting documents will be made available to qualified researchers upon reasonable request.
Requests must include a methodologically sound research proposal and will be reviewed by the study investigators.
Data will be provided after approval of the request and completion of an appropriate data-sharing agreement.
Access will be limited to data necessary to achieve the approved research objectives.
Typ podpůrných informací pro sdílení IPD
- PROTOKOL STUDY
- MÍZA
- ANALYTIC_CODE
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