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Isometric Exercise for Delayed Onset Muscle Soreness

2026년 5월 30일 업데이트: Onur Atakan Sekibağ, Istanbul Nisantasi University

Effects of Isometric Exercise on Recovery Following Experimentally Induced Delayed Onset Muscle Soreness: A Randomized Controlled Trial

The goal of this clinical trial is to learn whether isometric exercise can improve recovery following experimentally induced delayed onset muscle soreness (DOMS) in healthy young adults.

The main questions it aims to answer are:

  • Does isometric exercise reduce pain associated with delayed onset muscle soreness?
  • Does isometric exercise improve pressure pain threshold, knee joint range of motion, muscle strength, and recovery following delayed onset muscle soreness?

Researchers will compare participants performing an isometric exercise program with a control group receiving no intervention to determine whether isometric exercise improves recovery after experimentally induced DOMS.

Participants will:

  • Undergo a standardized exercise protocol to induce delayed onset muscle soreness.
  • Be randomly assigned to either an isometric exercise group or a control group.
  • Complete assessments of pain intensity, pressure pain threshold, knee range of motion, muscle strength, and thigh circumference.
  • Be evaluated before exercise, immediately after exercise, and on Days 1, 3, and 5 following DOMS induction.

연구 개요

상세 설명

Delayed onset muscle soreness (DOMS) is a common consequence of unaccustomed or high-intensity physical activity, particularly exercises involving eccentric muscle contractions. DOMS is characterized by pain, tenderness, temporary reductions in muscle function, decreased range of motion, and impaired physical performance, typically peaking between 24 and 72 hours after exercise.

Various recovery strategies have been investigated to reduce the symptoms of DOMS; however, evidence regarding the effectiveness of isometric exercise in facilitating recovery remains limited. Previous studies have suggested that isometric muscle contractions may induce analgesic effects and increase pressure pain thresholds in musculoskeletal conditions. Whether these effects can improve recovery following exercise-induced muscle damage and DOMS has not been fully established.

The purpose of this randomized controlled trial was to investigate the effects of an isometric exercise program on recovery following experimentally induced DOMS in healthy adults. DOMS was induced using a standardized drop-jump protocol. Participants were randomly assigned to either an isometric exercise group or a control group. Outcome assessments were performed before DOMS induction, immediately after exercise, and during follow-up evaluations on Days 1, 3, and 5.

The findings of this study may contribute to the understanding of the role of isometric exercise as a simple, low-cost, and clinically applicable recovery strategy following exercise-induced muscle soreness.

연구 유형

중재적

등록 (실제)

40

단계

  • 해당 없음

연락처 및 위치

이 섹션에서는 연구를 수행하는 사람들의 연락처 정보와 이 연구가 수행되는 장소에 대한 정보를 제공합니다.

연구 장소

    • Maslak
      • Istanbul, Maslak, 터키 (Türkiye), 34398
        • Istanbul Nisantasi University

참여기준

연구원은 적격성 기준이라는 특정 설명에 맞는 사람을 찾습니다. 이러한 기준의 몇 가지 예는 개인의 일반적인 건강 상태 또는 이전 치료입니다.

자격 기준

공부할 수 있는 나이

  • 성인

건강한 자원 봉사자를 받아들입니다

설명

Inclusion Criteria:

  • Active athletes competing in University sports teams.
  • Age between 18 and 30 years.
  • Participation in organized sports training at least three times per week for the previous six months.
  • No lower-extremity pain at the time of enrollment.
  • Ability to safely perform the exercise protocol used to induce delayed onset muscle soreness (DOMS).
  • Willingness to provide written informed consent.

Exclusion Criteria:

  • History of lower-extremity musculoskeletal injury within the previous 6 months.
  • Previous lower-extremity surgery.
  • Current musculoskeletal pain or injury affecting sports participation.
  • Neurological, rheumatological, cardiovascular, or systemic disorders affecting physical performance.
  • Use of analgesic, anti-inflammatory, or muscle-relaxant medications during the study period.
  • Participation in strenuous eccentric exercise within 72 hours prior to baseline testing.
  • Use of recovery interventions (e.g., massage, cryotherapy, compression garments, electrical stimulation) during the study period.
  • Inability to complete the exercise protocol or follow-up assessments.

공부 계획

이 섹션에서는 연구 설계 방법과 연구가 측정하는 내용을 포함하여 연구 계획에 대한 세부 정보를 제공합니다.

연구는 어떻게 설계됩니까?

디자인 세부사항

  • 주 목적: 치료
  • 할당: 무작위
  • 중재 모델: 병렬 할당
  • 마스킹: 더블

무기와 개입

참가자 그룹 / 팔
개입 / 치료
실험적: Isometric Exercise Group
Participants in this group underwent a standardized protocol to induce delayed onset muscle soreness (DOMS) and subsequently performed a structured quadriceps isometric exercise program during the recovery period.
Participants performed a structured quadriceps isometric exercise program following experimentally induced delayed onset muscle soreness. The exercise protocol was applied according to the study protocol throughout the recovery period.
가짜 비교기: Sham Exercise Group
Participants performed a sham exercise protocol following experimentally induced delayed onset muscle soreness. The sham intervention was designed to mimic the attention and participation associated with the experimental intervention without providing the intended therapeutic effect.
Participants performed a sham exercise protocol following experimentally induced delayed onset muscle soreness. The sham intervention was designed to mimic the attention and participation associated with the experimental intervention without providing the intended therapeutic effect.

연구는 무엇을 측정합니까?

주요 결과 측정

결과 측정
측정값 설명
기간
Pressure Pain Threshold
기간: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Pressure pain threshold measured using a digital pressure algometer following experimentally induced delayed onset muscle soreness (DOMS).
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Pain Intensity
기간: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Pain intensity assessed using a 10-cm Visual Analog Scale (VAS) following experimentally induced delayed onset muscle soreness (DOMS).
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.

2차 결과 측정

결과 측정
측정값 설명
기간
Knee Joint Range of Motion
기간: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Knee joint range of motion measured using a standard goniometer.
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Quadriceps Muscle Strength
기간: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Quadriceps muscle strength measured using a handheld dynamometer.
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Thigh Circumference
기간: Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Thigh circumference measured using a tape measure to assess exercise-induced swelling.
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.

공동 작업자 및 조사자

여기에서 이 연구와 관련된 사람과 조직을 찾을 수 있습니다.

간행물 및 유용한 링크

연구에 대한 정보 입력을 담당하는 사람이 자발적으로 이러한 간행물을 제공합니다. 이것은 연구와 관련된 모든 것에 관한 것일 수 있습니다.

연구 기록 날짜

이 날짜는 ClinicalTrials.gov에 대한 연구 기록 및 요약 결과 제출의 진행 상황을 추적합니다. 연구 기록 및 보고된 결과는 공개 웹사이트에 게시되기 전에 특정 품질 관리 기준을 충족하는지 확인하기 위해 국립 의학 도서관(NLM)에서 검토합니다.

연구 주요 날짜

연구 시작 (실제)

2025년 4월 1일

기본 완료 (실제)

2025년 7월 18일

연구 완료 (실제)

2025년 7월 18일

연구 등록 날짜

최초 제출

2026년 5월 30일

QC 기준을 충족하는 최초 제출

2026년 5월 30일

처음 게시됨 (실제)

2026년 6월 4일

연구 기록 업데이트

마지막 업데이트 게시됨 (실제)

2026년 6월 4일

QC 기준을 충족하는 마지막 업데이트 제출

2026년 5월 30일

마지막으로 확인됨

2026년 5월 1일

추가 정보

이 연구와 관련된 용어

개별 참가자 데이터(IPD) 계획

개별 참가자 데이터(IPD)를 공유할 계획입니까?

IPD 계획 설명

De-identified individual participant data underlying the published results may be made available upon reasonable request to the corresponding author, subject to institutional approval and applicable ethical requirements.

IPD 공유 기간

De-identified individual participant data, study protocol, statistical analysis plan, and analytic code will be available beginning 6 months after publication of the primary study results and ending 5 years after publication.

IPD 공유 액세스 기준

De-identified individual participant data and supporting documents will be made available to qualified researchers upon reasonable request. Requests must include a methodologically sound research proposal and will be reviewed by the study investigators. Data will be provided after approval of the request and completion of an appropriate data-sharing agreement. Access will be limited to data necessary to achieve the approved research objectives.

IPD 공유 지원 정보 유형

  • 연구_프로토콜
  • 수액
  • ANALYTIC_CODE

약물 및 장치 정보, 연구 문서

미국 FDA 규제 의약품 연구

아니

미국 FDA 규제 기기 제품 연구

아니

이 정보는 변경 없이 clinicaltrials.gov 웹사이트에서 직접 가져온 것입니다. 귀하의 연구 세부 정보를 변경, 제거 또는 업데이트하도록 요청하는 경우 register@clinicaltrials.gov. 문의하십시오. 변경 사항이 clinicaltrials.gov에 구현되는 즉시 저희 웹사이트에도 자동으로 업데이트됩니다. .

Isometric Exercise에 대한 임상 시험

구독하다