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Isometric Exercise for Delayed Onset Muscle Soreness

2026年5月30日 更新者:Onur Atakan Sekibağ、Istanbul Nisantasi University

Effects of Isometric Exercise on Recovery Following Experimentally Induced Delayed Onset Muscle Soreness: A Randomized Controlled Trial

The goal of this clinical trial is to learn whether isometric exercise can improve recovery following experimentally induced delayed onset muscle soreness (DOMS) in healthy young adults.

The main questions it aims to answer are:

  • Does isometric exercise reduce pain associated with delayed onset muscle soreness?
  • Does isometric exercise improve pressure pain threshold, knee joint range of motion, muscle strength, and recovery following delayed onset muscle soreness?

Researchers will compare participants performing an isometric exercise program with a control group receiving no intervention to determine whether isometric exercise improves recovery after experimentally induced DOMS.

Participants will:

  • Undergo a standardized exercise protocol to induce delayed onset muscle soreness.
  • Be randomly assigned to either an isometric exercise group or a control group.
  • Complete assessments of pain intensity, pressure pain threshold, knee range of motion, muscle strength, and thigh circumference.
  • Be evaluated before exercise, immediately after exercise, and on Days 1, 3, and 5 following DOMS induction.

調査の概要

詳細な説明

Delayed onset muscle soreness (DOMS) is a common consequence of unaccustomed or high-intensity physical activity, particularly exercises involving eccentric muscle contractions. DOMS is characterized by pain, tenderness, temporary reductions in muscle function, decreased range of motion, and impaired physical performance, typically peaking between 24 and 72 hours after exercise.

Various recovery strategies have been investigated to reduce the symptoms of DOMS; however, evidence regarding the effectiveness of isometric exercise in facilitating recovery remains limited. Previous studies have suggested that isometric muscle contractions may induce analgesic effects and increase pressure pain thresholds in musculoskeletal conditions. Whether these effects can improve recovery following exercise-induced muscle damage and DOMS has not been fully established.

The purpose of this randomized controlled trial was to investigate the effects of an isometric exercise program on recovery following experimentally induced DOMS in healthy adults. DOMS was induced using a standardized drop-jump protocol. Participants were randomly assigned to either an isometric exercise group or a control group. Outcome assessments were performed before DOMS induction, immediately after exercise, and during follow-up evaluations on Days 1, 3, and 5.

The findings of this study may contribute to the understanding of the role of isometric exercise as a simple, low-cost, and clinically applicable recovery strategy following exercise-induced muscle soreness.

研究の種類

介入

入学 (実際)

40

段階

  • 適用できない

連絡先と場所

このセクションには、調査を実施する担当者の連絡先の詳細と、この調査が実施されている場所に関する情報が記載されています。

研究場所

参加基準

研究者は、適格基準と呼ばれる特定の説明に適合する人を探します。これらの基準のいくつかの例は、人の一般的な健康状態または以前の治療です。

適格基準

就学可能な年齢

  • 大人

健康ボランティアの受け入れ

はい

説明

Inclusion Criteria:

  • Active athletes competing in University sports teams.
  • Age between 18 and 30 years.
  • Participation in organized sports training at least three times per week for the previous six months.
  • No lower-extremity pain at the time of enrollment.
  • Ability to safely perform the exercise protocol used to induce delayed onset muscle soreness (DOMS).
  • Willingness to provide written informed consent.

Exclusion Criteria:

  • History of lower-extremity musculoskeletal injury within the previous 6 months.
  • Previous lower-extremity surgery.
  • Current musculoskeletal pain or injury affecting sports participation.
  • Neurological, rheumatological, cardiovascular, or systemic disorders affecting physical performance.
  • Use of analgesic, anti-inflammatory, or muscle-relaxant medications during the study period.
  • Participation in strenuous eccentric exercise within 72 hours prior to baseline testing.
  • Use of recovery interventions (e.g., massage, cryotherapy, compression garments, electrical stimulation) during the study period.
  • Inability to complete the exercise protocol or follow-up assessments.

研究計画

このセクションでは、研究がどのように設計され、研究が何を測定しているかなど、研究計画の詳細を提供します。

研究はどのように設計されていますか?

デザインの詳細

  • 主な目的:処理
  • 割り当て:ランダム化
  • 介入モデル:並列代入
  • マスキング:ダブル

武器と介入

参加者グループ / アーム
介入・治療
実験的:Isometric Exercise Group
Participants in this group underwent a standardized protocol to induce delayed onset muscle soreness (DOMS) and subsequently performed a structured quadriceps isometric exercise program during the recovery period.
Participants performed a structured quadriceps isometric exercise program following experimentally induced delayed onset muscle soreness. The exercise protocol was applied according to the study protocol throughout the recovery period.
偽コンパレータ:Sham Exercise Group
Participants performed a sham exercise protocol following experimentally induced delayed onset muscle soreness. The sham intervention was designed to mimic the attention and participation associated with the experimental intervention without providing the intended therapeutic effect.
Participants performed a sham exercise protocol following experimentally induced delayed onset muscle soreness. The sham intervention was designed to mimic the attention and participation associated with the experimental intervention without providing the intended therapeutic effect.

この研究は何を測定していますか?

主要な結果の測定

結果測定
メジャーの説明
時間枠
Pressure Pain Threshold
時間枠:Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Pressure pain threshold measured using a digital pressure algometer following experimentally induced delayed onset muscle soreness (DOMS).
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Pain Intensity
時間枠:Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Pain intensity assessed using a 10-cm Visual Analog Scale (VAS) following experimentally induced delayed onset muscle soreness (DOMS).
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.

二次結果の測定

結果測定
メジャーの説明
時間枠
Knee Joint Range of Motion
時間枠:Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Knee joint range of motion measured using a standard goniometer.
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Quadriceps Muscle Strength
時間枠:Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Quadriceps muscle strength measured using a handheld dynamometer.
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Thigh Circumference
時間枠:Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.
Thigh circumference measured using a tape measure to assess exercise-induced swelling.
Baseline, immediately after exercise, Day 1, Day 3, and Day 5 following DOMS induction.

協力者と研究者

ここでは、この調査に関係する人々や組織を見つけることができます。

出版物と役立つリンク

研究に関する情報を入力する責任者は、自発的にこれらの出版物を提供します。これらは、研究に関連するあらゆるものに関するものである可能性があります。

研究記録日

これらの日付は、ClinicalTrials.gov への研究記録と要約結果の提出の進捗状況を追跡します。研究記録と報告された結果は、国立医学図書館 (NLM) によって審査され、公開 Web サイトに掲載される前に、特定の品質管理基準を満たしていることが確認されます。

主要日程の研究

研究開始 (実際)

2025年4月1日

一次修了 (実際)

2025年7月18日

研究の完了 (実際)

2025年7月18日

試験登録日

最初に提出

2026年5月30日

QC基準を満たした最初の提出物

2026年5月30日

最初の投稿 (実際)

2026年6月4日

学習記録の更新

投稿された最後の更新 (実際)

2026年6月4日

QC基準を満たした最後の更新が送信されました

2026年5月30日

最終確認日

2026年5月1日

詳しくは

本研究に関する用語

個々の参加者データ (IPD) の計画

個々の参加者データ (IPD) を共有する予定はありますか?

はい

IPD プランの説明

De-identified individual participant data underlying the published results may be made available upon reasonable request to the corresponding author, subject to institutional approval and applicable ethical requirements.

IPD 共有時間枠

De-identified individual participant data, study protocol, statistical analysis plan, and analytic code will be available beginning 6 months after publication of the primary study results and ending 5 years after publication.

IPD 共有アクセス基準

De-identified individual participant data and supporting documents will be made available to qualified researchers upon reasonable request. Requests must include a methodologically sound research proposal and will be reviewed by the study investigators. Data will be provided after approval of the request and completion of an appropriate data-sharing agreement. Access will be limited to data necessary to achieve the approved research objectives.

IPD 共有サポート情報タイプ

  • STUDY_PROTOCOL
  • SAP
  • ANALYTIC_CODE

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