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Effects of Whole Body Vibration on Quadriceps Function, Landing Biomechanics, and Performance in Individuals With ACL Reconstruction

2026年6月25日 更新者:University of North Carolina, Chapel Hill

Use of Whole-body Vibration to Acutely Improve Landing Biomechanics In Individuals With Anterior Cruciate Ligament Reconstruction (ACLR)

Individuals who undergo anterior cruciate ligament reconstruction (ACLR) are at heightened risk of secondary anterior cruciate ligament (ACL) injury (e.g. additional injury to the ACL in either knee). One of the primary physiological consequences of ACLR is the presence of quadriceps dysfunction (i.e. reduced activation and strength) which has been linked to altered gait and landing biomechanics. Aberrant landing biomechanics have been associated with an increased risk of both primary and secondary ACL injury, thus additional research is needed to evaluate the efficacy of treatments aimed to reduce quadriceps dysfunction and restore adequate landing biomechanics in attempts to reduce secondary ACL injury. Whole-body Vibration (WBV) has demonstrated success in improving quadriceps function and gait biomechanics in individuals with ACLR, however its effectiveness on landing biomechanics is unknown. To evaluate the acute effects of WBV on landing biomechanics in those with ACLR, a non-randomized crossover-controlled trial was conducted to determine if a single bout of WBV improved landing biomechanics greater than a control condition. Participants completed two separate testing sessions (separated by at least one week) in which measures of quadriceps function and landing biomechanics were assessed before and after either a control (no WBV) or WBV intervention. Separate linear mixed-effects models of post-test values for each dependent outcome were conducted with condition (control vs WBV) and limb (ACLR vs Uninvolved) as an interaction term, and each condition pre-test values and time post-ACLR as fixed effect covariates and a random effect of subject. The investigators expect to observe a significant improvement in landing biomechanics following WBV compared to the control condition.

研究概览

研究类型

介入性

注册 (实际的)

36

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息,以及有关进行该研究的地点的信息。

学习地点

    • North Carolina
      • Chapel Hill、North Carolina、美国、27599
        • Univesrity of North Carolina at Chapel HIll MOTION Science Institute

参与标准

研究人员寻找符合特定描述的人,称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

  • 成人

接受健康志愿者

不

描述

Inclusion Criteria:

  • Between the ages of 18-35
  • History of primary, unilateral ACLR
  • Medically cleared for unrestricted physical activity

Exclusion Criteria:

  • More than 5 years removed from ACLR
  • Currently pregnant
  • History of other lower extremity surgery
  • History of lower extremity injury in previous 6 months
  • History of neurological disorder
  • Maximal isometric quadriceps torque > 3.0 Nm/kg in the ACLR limb

学习计划

本节提供研究计划的详细信息,包括研究的设计方式和研究的衡量标准。

研究是如何设计的?

设计细节

  • 主要用途:基础科学
  • 分配:非随机化
  • 介入模型:交叉作业
  • 屏蔽:双倍的

武器和干预

参与者组/臂
干预/治疗
实验性的:Whole body vibration followed by No Intervention (Control)
Participants in this arm will receive Whole Body Vibration followed by a washout period of 1 week, then receive the Sham Whole body vibration (Control). Each condition will be evaluated in a single session (i.e. acute effects).
Participants will stand on a WBV platform in a mini-squat position while vibration is applied during six 60-second bouts with 2 minutes of rest between each bout. WBV will be delivered at an acceleration of 2g and a frequency of 30 Hz.
Participants will stand on a WBV platform in a mini-squat position during six 60-second bouts with 2 minutes of rest between each bout. No vibration will be applied.
实验性的:Sham Whole body vibration (Control) followed by Whole Body Vibration
Participants in this arm will receive Sham Whole body vibration (Control) followed by a washout period of 1 week, then receive Whole Body Vibration. Each condition will be evaluated in a single session (i.e. acute effects).
Participants will stand on a WBV platform in a mini-squat position while vibration is applied during six 60-second bouts with 2 minutes of rest between each bout. WBV will be delivered at an acceleration of 2g and a frequency of 30 Hz.
Participants will stand on a WBV platform in a mini-squat position during six 60-second bouts with 2 minutes of rest between each bout. No vibration will be applied.

研究衡量的是什么?

主要结果指标

结果测量
措施说明
大体时间
Internal Knee Adduction Moment (KAM)
大体时间:Separate values prior to and immediately following the intervention (within 5 minutes).
Peak value during landing in both single-leg and double-leg tasks averaged over 3 trials and normalized to the product of body weight and height
Separate values prior to and immediately following the intervention (within 5 minutes).
Internal Knee Extension Moment (KEM)
大体时间:Separate values prior to and immediately following the intervention (within 5 minutes).
Peak value during landing in both single-leg and double-leg tasks averaged over 3 trials and normalized to a product of body weight*height
Separate values prior to and immediately following the intervention (within 5 minutes).
Knee Flexion Angle (KFA)
大体时间:Separate values prior to and immediately following the intervention (within 5 minutes).
Peak value during landing in both single-leg and double-leg tasks averaged over 3 trials
Separate values prior to and immediately following the intervention (within 5 minutes).

次要结果测量

结果测量
措施说明
大体时间
Dynamic Postural Control
大体时间:Separate values prior to and immediately following the intervention (within 5 minutes).
Time-to-stabilization during single-leg landing
Separate values prior to and immediately following the intervention (within 5 minutes).
Vertical Ground Reaction Force
大体时间:Separate values prior to and immediately following the intervention (within 5 minutes).
Peak value during landing in both single-leg and double-leg tasks
Separate values prior to and immediately following the intervention (within 5 minutes).
Frontal Plane Kinematics
大体时间:Separate values prior to and immediately following the intervention (within 5 minutes).
Peak value during landing in both single-leg and double-leg tasks
Separate values prior to and immediately following the intervention (within 5 minutes).

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

调查人员

  • 首席研究员:Derek Dewig、University of North Carolina, Chapel Hill

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查,以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (实际的)

2021年9月1日

初级完成 (实际的)

2022年4月22日

研究完成 (实际的)

2022年5月10日

研究注册日期

首次提交

2026年6月10日

首先提交符合 QC 标准的

2026年6月25日

首次发布 (实际的)

2026年7月2日

研究记录更新

最后更新发布 (实际的)

2026年7月2日

上次提交的符合 QC 标准的更新

2026年6月25日

最后验证

2026年6月1日

更多信息

与本研究相关的术语

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)?

是的

IPD 计划说明

Deidentified individual data that supports the results will be shared beginning 9 and continuing for 36 months following publication provided the investigator who proposes to use the data has approval from an Institutional Review Board (IRB), Independent Ethics Committee (IEC), or Research Ethics Board (REB), as applicable, and executes a data use/sharing agreement with UNC.

IPD 共享时间框架

IPD will be available beginning 9 and continuing for 36 months following publication.

IPD 共享访问标准

Investigator has approved IRB, IEC, or REB and an executed data use/sharing agreement with UNC.

IPD 共享支持信息类型

  • 研究方案

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

此信息直接从 clinicaltrials.gov 网站检索,没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求,请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改,我们的网站上也会自动更新.

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