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Effects of Whole Body Vibration on Quadriceps Function, Landing Biomechanics, and Performance in Individuals With ACL Reconstruction

25 juni 2026 bijgewerkt door: University of North Carolina, Chapel Hill

Use of Whole-body Vibration to Acutely Improve Landing Biomechanics In Individuals With Anterior Cruciate Ligament Reconstruction (ACLR)

Individuals who undergo anterior cruciate ligament reconstruction (ACLR) are at heightened risk of secondary anterior cruciate ligament (ACL) injury (e.g. additional injury to the ACL in either knee). One of the primary physiological consequences of ACLR is the presence of quadriceps dysfunction (i.e. reduced activation and strength) which has been linked to altered gait and landing biomechanics. Aberrant landing biomechanics have been associated with an increased risk of both primary and secondary ACL injury, thus additional research is needed to evaluate the efficacy of treatments aimed to reduce quadriceps dysfunction and restore adequate landing biomechanics in attempts to reduce secondary ACL injury. Whole-body Vibration (WBV) has demonstrated success in improving quadriceps function and gait biomechanics in individuals with ACLR, however its effectiveness on landing biomechanics is unknown. To evaluate the acute effects of WBV on landing biomechanics in those with ACLR, a non-randomized crossover-controlled trial was conducted to determine if a single bout of WBV improved landing biomechanics greater than a control condition. Participants completed two separate testing sessions (separated by at least one week) in which measures of quadriceps function and landing biomechanics were assessed before and after either a control (no WBV) or WBV intervention. Separate linear mixed-effects models of post-test values for each dependent outcome were conducted with condition (control vs WBV) and limb (ACLR vs Uninvolved) as an interaction term, and each condition pre-test values and time post-ACLR as fixed effect covariates and a random effect of subject. The investigators expect to observe a significant improvement in landing biomechanics following WBV compared to the control condition.

Studie Overzicht

Toestand

Voltooid

Conditie

Interventie / Behandeling

Studietype

Ingrijpend

Inschrijving (Werkelijk)

36

Fase

  • Niet toepasbaar

Contacten en locaties

In dit gedeelte vindt u de contactgegevens van degenen die het onderzoek uitvoeren en informatie over waar dit onderzoek wordt uitgevoerd.

Studie Locaties

  • Verenigde Staten
    • North Carolina
      • Chapel Hill, North Carolina, Verenigde Staten, 27599
        • Univesrity of North Carolina at Chapel HIll MOTION Science Institute

Deelname Criteria

Onderzoekers zoeken naar mensen die aan een bepaalde beschrijving voldoen, de zogenaamde geschiktheidscriteria. Enkele voorbeelden van deze criteria zijn iemands algemene gezondheidstoestand of eerdere behandelingen.

Geschiktheidscriteria

Leeftijden die in aanmerking komen voor studie

  • Volwassen

Accepteert gezonde vrijwilligers

Nee

Beschrijving

Inclusion Criteria:

  • Between the ages of 18-35
  • History of primary, unilateral ACLR
  • Medically cleared for unrestricted physical activity

Exclusion Criteria:

  • More than 5 years removed from ACLR
  • Currently pregnant
  • History of other lower extremity surgery
  • History of lower extremity injury in previous 6 months
  • History of neurological disorder
  • Maximal isometric quadriceps torque > 3.0 Nm/kg in the ACLR limb

Studie plan

Dit gedeelte bevat details van het studieplan, inclusief hoe de studie is opgezet en wat de studie meet.

Hoe is de studie opgezet?

Ontwerpdetails

  • Primair doel: Fundamentele wetenschap
  • Toewijzing: Niet-gerandomiseerd
  • Interventioneel model: Crossover-opdracht
  • Masker: Dubbele

Wapens en interventies

Deelnemersgroep / Arm
Interventie / Behandeling
Experimenteel: Whole body vibration followed by No Intervention (Control)
Participants in this arm will receive Whole Body Vibration followed by a washout period of 1 week, then receive the Sham Whole body vibration (Control). Each condition will be evaluated in a single session (i.e. acute effects).
Ander: Whole body vibration (WBV)
Participants will stand on a WBV platform in a mini-squat position while vibration is applied during six 60-second bouts with 2 minutes of rest between each bout. WBV will be delivered at an acceleration of 2g and a frequency of 30 Hz.
Ander: Sham Whole body vibration
Participants will stand on a WBV platform in a mini-squat position during six 60-second bouts with 2 minutes of rest between each bout. No vibration will be applied.
Experimenteel: Sham Whole body vibration (Control) followed by Whole Body Vibration
Participants in this arm will receive Sham Whole body vibration (Control) followed by a washout period of 1 week, then receive Whole Body Vibration. Each condition will be evaluated in a single session (i.e. acute effects).
Ander: Whole body vibration (WBV)
Participants will stand on a WBV platform in a mini-squat position while vibration is applied during six 60-second bouts with 2 minutes of rest between each bout. WBV will be delivered at an acceleration of 2g and a frequency of 30 Hz.
Ander: Sham Whole body vibration
Participants will stand on a WBV platform in a mini-squat position during six 60-second bouts with 2 minutes of rest between each bout. No vibration will be applied.

Wat meet het onderzoek?

Primaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Internal Knee Adduction Moment (KAM)
Tijdsspanne: Separate values prior to and immediately following the intervention (within 5 minutes).
Peak value during landing in both single-leg and double-leg tasks averaged over 3 trials and normalized to the product of body weight and height
Separate values prior to and immediately following the intervention (within 5 minutes).
Internal Knee Extension Moment (KEM)
Tijdsspanne: Separate values prior to and immediately following the intervention (within 5 minutes).
Peak value during landing in both single-leg and double-leg tasks averaged over 3 trials and normalized to a product of body weight*height
Separate values prior to and immediately following the intervention (within 5 minutes).
Knee Flexion Angle (KFA)
Tijdsspanne: Separate values prior to and immediately following the intervention (within 5 minutes).
Peak value during landing in both single-leg and double-leg tasks averaged over 3 trials
Separate values prior to and immediately following the intervention (within 5 minutes).

Secundaire uitkomstmaten

Uitkomstmaat
Maatregel Beschrijving
Tijdsspanne
Dynamic Postural Control
Tijdsspanne: Separate values prior to and immediately following the intervention (within 5 minutes).
Time-to-stabilization during single-leg landing
Separate values prior to and immediately following the intervention (within 5 minutes).
Vertical Ground Reaction Force
Tijdsspanne: Separate values prior to and immediately following the intervention (within 5 minutes).
Peak value during landing in both single-leg and double-leg tasks
Separate values prior to and immediately following the intervention (within 5 minutes).
Frontal Plane Kinematics
Tijdsspanne: Separate values prior to and immediately following the intervention (within 5 minutes).
Peak value during landing in both single-leg and double-leg tasks
Separate values prior to and immediately following the intervention (within 5 minutes).

Medewerkers en onderzoekers

Hier vindt u mensen en organisaties die betrokken zijn bij dit onderzoek.

Sponsor

University of North Carolina, Chapel Hill

Onderzoekers

  • Hoofdonderzoeker: Derek Dewig, University of North Carolina, Chapel Hill

Studie record data

Deze datums volgen de voortgang van het onderzoeksdossier en de samenvatting van de ingediende resultaten bij ClinicalTrials.gov. Studieverslagen en gerapporteerde resultaten worden beoordeeld door de National Library of Medicine (NLM) om er zeker van te zijn dat ze voldoen aan specifieke kwaliteitscontrolenormen voordat ze op de openbare website worden geplaatst.

Bestudeer belangrijke data

Studie start (Werkelijk)

1 september 2021

Primaire voltooiing (Werkelijk)

22 april 2022

Studie voltooiing (Werkelijk)

10 mei 2022

Studieregistratiedata

Eerst ingediend

10 juni 2026

Eerst ingediend dat voldeed aan de QC-criteria

25 juni 2026

Eerst geplaatst (Werkelijk)

2 juli 2026

Updates van studierecords

Laatste update geplaatst (Werkelijk)

2 juli 2026

Laatste update ingediend die voldeed aan QC-criteria

25 juni 2026

Laatst geverifieerd

1 juni 2026

Meer informatie

Termen gerelateerd aan deze studie

Trefwoorden

Aanvullende relevante MeSH-voorwaarden

Andere studie-ID-nummers

  • 21-0305

Plan Individuele Deelnemersgegevens (IPD)

Bent u van plan om gegevens van individuele deelnemers (IPD) te delen?

JA

Beschrijving IPD-plan

Deidentified individual data that supports the results will be shared beginning 9 and continuing for 36 months following publication provided the investigator who proposes to use the data has approval from an Institutional Review Board (IRB), Independent Ethics Committee (IEC), or Research Ethics Board (REB), as applicable, and executes a data use/sharing agreement with UNC.

IPD-tijdsbestek voor delen

IPD will be available beginning 9 and continuing for 36 months following publication.

IPD-toegangscriteria voor delen

Investigator has approved IRB, IEC, or REB and an executed data use/sharing agreement with UNC.

IPD delen Ondersteunend informatietype

  • LEERPROTOCOOL

Informatie over medicijnen en apparaten, studiedocumenten

Bestudeert een door de Amerikaanse FDA gereguleerd geneesmiddel

Nee

Bestudeert een door de Amerikaanse FDA gereguleerd apparaatproduct

Nee

Deze informatie is zonder wijzigingen rechtstreeks van de website clinicaltrials.gov gehaald. Als u verzoeken heeft om uw onderzoeksgegevens te wijzigen, te verwijderen of bij te werken, neem dan contact op met register@clinicaltrials.gov. Zodra er een wijziging wordt doorgevoerd op clinicaltrials.gov, wordt deze ook automatisch bijgewerkt op onze website .

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