Evaluation of The Effect of Injectable Platelet-rich Fibrin With Collagen Membrane in Miller Class II Gingival Recession Coverage
This study aims to evaluate the effect of injectable Platelet-Rich Fibrin (i-PRF) in combination with collagen membrane in the treatment of Miller Class II gingival recession. Gingival recession is a common periodontal condition characterized by apical displacement of the gingival margin, which may lead to aesthetic concerns, root hypersensitivity, and increased risk of root caries.
The study will include patients diagnosed with Miller Class II gingival recession. Participants will be treated using a regenerative periodontal surgical approach involving coronally advanced flap combined with injectable platelet-rich fibrin and collagen membrane. Clinical parameters such as recession depth, clinical attachment level, and keratinized tissue width will be evaluated before and after treatment at specific follow-up intervals.
The objective is to compare the effectiveness of this combined regenerative approach in improving root coverage and soft tissue healing, and to assess its potential benefits in periodontal regeneration and esthetic outcomes.
研究概览
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
-
-
Gharbia Governorate
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Tanta、Gharbia Governorate、埃及
- Faculty of dentistry ,Tanta university
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-
参与标准
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
描述
Inclusion criteria:
Both males and females of age ≥ 18
Exclusion criteria:
History of systemic diseases (i.e. diabetes, autoimmune dysfunction, prolonged cortisone therapy, or chemotherapy) that contraindicated periodontal surgical treatment.
学习计划
研究是如何设计的?
设计细节
- 主要用途:治疗
- 分配:随机化
- 介入模型:并行分配
- 屏蔽:单身的
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的:Group 1
i-PRF +collagen membrane
|
Application of injectable platelet -rich fibrin (I-PRF) in combination with a collagen membrane during the surgical procedure to enhance soft and hard tissue healing
其他名称:
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有源比较器:Group 2
CAF+SCTG
|
coronally advanced flap surgery combined with a subepithelial connective tissue graft for the treatment of gingival recession defects
其他名称:
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Keratinized Tissue Thickness
大体时间:Baseline, 1 month ,3 months and 6 months after surgery
|
measured in millimeters (mm) using a endodontic file
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Baseline, 1 month ,3 months and 6 months after surgery
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次要结果测量
结果测量 |
大体时间 |
|---|---|
|
Recession Depth (RD)
大体时间:baseline,1 month,3 months,6 months after surgery
|
baseline,1 month,3 months,6 months after surgery
|
|
Recession Width (RW)
大体时间:Baseline,1 month,3 months ,and 6 months after surgery
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Baseline,1 month,3 months ,and 6 months after surgery
|
|
keratinized Tissue Height (KTH)
大体时间:Baseline, 1 month, 3 months, 6 months after surgery
|
Baseline, 1 month, 3 months, 6 months after surgery
|
|
Probing Pocket Depth (PPD)
大体时间:Baseline and 6 months after surgery
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Baseline and 6 months after surgery
|
合作者和调查者
调查人员
- 首席研究员:Shereen Abdelmoula Ali、Faculty of dentistry ,Tanta university .Tanta, Eygpt
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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