Assessment of Diaphragmatic Function After Stellate Ganglion Block
2026年7月22日 更新者：Jose Manuel López González
Diaphragmatic Ultrasound and Spirometry After Ultrasound-guided Stellate Ganglion Block: a Prospective Observational Study
The objective of our study was to evaluate the incidence of hemidiaphragmatic paralysis after ultrasound-guided stellate ganglion block (US-SGB) by assessing diaphragmatic excursion and diaphragmatic thickening fraction using diaphragm ultrasound.
研究概览
详细说明
A prospective, single-center observational study was designed with the aim of evaluating diaphragmatic excursion and diaphragmatic thickening fraction, measured by ultrasound before and 30 minutes after US-SGB performed with 10 mL of 0.25% levobupivacaíne.
研究类型
观察性的
注册 (实际的)
15
联系人和位置
本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。
学习地点
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Principality of Asturias
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Oviedo、Principality of Asturias、西班牙、33001
- FINBA
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参与标准
研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
不
取样方法
非概率样本
研究人群
After approval of the study by the Principality of Asturias Drug Research Ethics Committee (CEImPA), Spain, and obtaining informed consent from the participants, all consecutive patients undergoing a first diagnostic US-SGB for sympathetic nervous system-mediated disorders were prospectively included.
描述
Inclusion Criteria:
- patients over 18 years of age.
- patients with sympathetic nervous system-mediated disorders.
Exclusion Criteria:
- patients younger than 18 years of age.
- patients with severe chronic obstructive pulmonary disease.
- previous diaphragmatic paralysis or neuromuscular disease.
- inability to undergo diaphragmatic ultrasound.
- patients with neck anatomy considered unsuitable for the procedure (including previous neck surgery, burns, extensive scarring or large goiters resulting in distortion of normal cervical anatomy).
- contraindications to the interventional technique (such as infection at the puncture site, or refusal to provide consent).
学习计划
本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。
研究是如何设计的？
设计细节
队列和干预
团体/队列 |
干预/治疗 |
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US-SGB
Patients with sympathetic nervous system-mediated disorders of the upper limb undergoing a first diagnostic ultrasound-guided stellate ganglion block (US-SGB).
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US-SGB was performed at the C7 level using 10 ml of 0.25% levobupivacaíne.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Diaphragmatic excursion
大体时间：The diaphragmatic excursion, assessed by diaphragm ultrasound before and 30 minutes after US-SGB.
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Excursion of the diaphragmatic dome was assessed by a pulmonologist experienced in diaphragm ultrasound assessment.
Once the dome was identified, excursion was measured in M-mode as the distance, in centimeters, between the end-expiratory and end-inspiratory positions during a vital capacity manoeuvre.
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The diaphragmatic excursion, assessed by diaphragm ultrasound before and 30 minutes after US-SGB.
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Diaphragmatic thickening fraction
大体时间：The diaphragmatic thickening, assessed by diaphragm ultrasound before and 30 minutes after US-SGB.
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The diaphragmatic thickening fraction was assessed by a pulmonologist experienced in diaphragm ultrasound assessment. Diaphragm thickness was measured, in centimeters, at end-inspiration and end-expiration during a vital capacity manoeuvre. Thickening fraction was calculated using the following formula and expressed as a percentaje: Thickening fraction = [(thickness at end-inspiration - thickness at end-expiration) / thickness at end-expiration] x 100. |
The diaphragmatic thickening, assessed by diaphragm ultrasound before and 30 minutes after US-SGB.
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Forced vital capacity (FVC)
大体时间：Spirometric parameters measured at baseline and 1 hour after US-SGB.
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Measure of the maximum exhaled volume of air (in liters, L) after a deep breath, on spirometry performed using a pneumotachograph spirometer.
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Spirometric parameters measured at baseline and 1 hour after US-SGB.
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Forced expiratory volume in 1 second (FEV1)
大体时间：Spirometric parameters measured at baseline and 1 hour after US-SGB.
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Measure of the exhaled air volume (in liters, L) in the first second of the spirometry, performed using a pneumotachograph spirometer
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Spirometric parameters measured at baseline and 1 hour after US-SGB.
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Tiffeneau index (FEV1/FVC ratio)
大体时间：Spirometric parameters measured at baseline and 1 hour after US-SGB.
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Ratio between the aforementioned FEV1 and FVC expressed in percentage (%), derived from the parameters obtained on spirometry.
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Spirometric parameters measured at baseline and 1 hour after US-SGB.
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Peripheral oxygen saturation (SpO2)
大体时间：Measured at baseline and 1 hour after US-SGB.
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Peripheral blood oxygen saturation (SpO2) expressed in percentage (%), measured using a digital pulse oximeter.
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Measured at baseline and 1 hour after US-SGB.
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合作者和调查者
在这里您可以找到参与这项研究的人员和组织。
调查人员
- 首席研究员：Daniel García Iglesias, MD, PhD、Central University Hospital of Asturias, 33001, Spain
出版物和有用的链接
负责输入研究信息的人员自愿提供这些出版物。这些可能与研究有关。
一般刊物
- Rafla C, Zitek T, Shalaby M. A systematic review of the respiratory effects of ultrasound-guided phrenic nerve block. Anesth Pain Med (Seoul). 2025 Oct;20(4):371-383. doi: 10.17085/apm.25214. Epub 2025 Sep 26.
- Santana PV, Cardenas LZ, Albuquerque ALP, Carvalho CRR, Caruso P. Diaphragmatic ultrasound: a review of its methodological aspects and clinical uses. J Bras Pneumol. 2020 Nov 20;46(6):e20200064. doi: 10.36416/1806-3756/e20200064. eCollection 2020.
- Sferrazza Papa GF, Pellegrino GM, Di Marco F, Imeri G, Brochard L, Goligher E, Centanni S. A Review of the Ultrasound Assessment of Diaphragmatic Function in Clinical Practice. Respiration. 2016;91(5):403-11. doi: 10.1159/000446518. Epub 2016 May 25.
- Tsai EH, Nunez-Rodriguez E, Cata JP. Stellate ganglion block in perioperative practice: a narrative review. Br J Anaesth. 2026 Jan;136(1):179-196. doi: 10.1016/j.bja.2025.07.095. Epub 2025 Sep 29.
- Motazedian P, Quinn N, Wells GA, Beauregard N, Lam E, Mathieu ME, Knoll W, Prosperi-Porta G, Ly V, Parlow S, Di Santo P, Abdel-Razek O, Jung R, Simard T, Jentzer JC, Mathew R, Ramirez FD, Hibbert B. Efficacy of stellate ganglion block in treatment of electrical storm: a systematic review and meta-analysis. Sci Rep. 2024 Oct 21;14(1):24719. doi: 10.1038/s41598-024-76663-9.
- Kirkpatrick K, Khan MH, Deng Y, Shah KB. A Review of Stellate Ganglion Block as an Adjunctive Treatment Modality. Cureus. 2023 Feb 19;15(2):e35174. doi: 10.7759/cureus.35174. eCollection 2023 Feb.
研究记录日期
这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。
研究主要日期
学习开始 (实际的)
2024年12月1日
初级完成 (实际的)
2025年12月10日
研究完成 (实际的)
2026年6月1日
研究注册日期
首次提交
2026年7月15日
首先提交符合 QC 标准的
2026年7月22日
首次发布 (实际的)
2026年7月23日
研究记录更新
最后更新发布 (实际的)
2026年7月23日
上次提交的符合 QC 标准的更新
2026年7月22日
最后验证
2026年7月1日
更多信息
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