Assessment of Retinal Microvascular Changes by OCT Angiography in Diabetic Retinopathy
Assessment of Retinal Microvascular Changes by OCT Angiography and Their Correlation With Visual Acuity and Glycemic Control Across Different Stages of Diabetic Retinopathy
研究概览
地位
条件
详细说明
Diabetic retinopathy is one of the leading causes of visual impairment worldwide. Optical coherence tomography angiography (OCTA) is a non-invasive imaging technique that provides detailed visualization of the retinal microvasculature without the need for dye injection.
This observational cross-sectional study will be conducted at the Department of Ophthalmology, Faculty of Medicine, Sohag University. Adult patients diagnosed with different stages of diabetic retinopathy will undergo comprehensive ophthalmic examination, including best-corrected visual acuity assessment, fundus examination, OCT, and OCT angiography.
Retinal microvascular parameters, including vessel density in the superficial and deep capillary plexuses and the foveal avascular zone (FAZ), will be measured. HbA1c values will be recorded to assess glycemic control.
The primary objective is to evaluate retinal microvascular changes detected by OCTA and determine their correlation with visual acuity and glycemic control across different stages of diabetic retinopathy.
研究类型
注册 (估计的)
联系人和位置
学习联系方式
- 姓名：Omnia Mohamed Abdel Aziz, M.B.BCh
- 电话号码：01011000347
- 邮箱：01011000347a@gmail.com
学习地点
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Sohag、埃及
- 招聘中
- Sohag Ophthalmology Hospital
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接触：
- Omnia Mohamed Abdel Aziz, M.B.B.Ch
- 电话号码：+201011000347
- 邮箱：01011000347a@gmail.com
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首席研究员：
- Omnia Mohamed Abdel Aziz, M.B.B.Ch
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参与标准
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
取样方法
研究人群
描述
Inclusion Criteria:
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Inclusion Criteria:
- Adults aged 18 to 80 years.
- Patients diagnosed with diabetic retinopathy.
- Ability to undergo complete ophthalmic examination including OCT and OCT angiography.
- Availability of HbA1c measurement within the study period.
- Ability and willingness to provide written informed consent.
Exclusion Criteria:
- Previous vitreoretinal surgery.
- Significant media opacity affecting image quality (e.g., dense cataract or vitreous hemorrhage).
- Other retinal vascular diseases (e.g., retinal vein occlusion).
- Glaucoma or optic nerve diseases affecting visual function.
- High myopia (>6 diopters).
- Poor-quality OCTA images due to motion artifacts or poor fixation.
- Refusal or inability to provide informed consent.
Exclusion Criteria:
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学习计划
研究是如何设计的？
设计细节
研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Retinal Microvascular Changes Measured by OCT Angiography
大体时间：Baseline
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Assessment of retinal microvascular parameters including vessel density in the superficial and deep capillary plexuses and the foveal avascular zone (FAZ) using OCT angiography, and their correlation with best-corrected visual acuity and HbA1c.
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Baseline
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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Correlation Between OCTA Parameters, Visual Acuity, and Glycemic Control
大体时间：Baseline
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Evaluation of the association between OCTA-derived retinal microvascular parameters, best-corrected visual acuity, HbA1c level, and the stage of diabetic retinopathy.
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Baseline
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合作者和调查者
调查人员
- 学习椅：Ahmad Gad Kamel、Faculty of medicine, Sohag university
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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