此页面是自动翻译的，不保证翻译的准确性。请参阅 英文版 对于源文本。

Effects of Exercise Snacks on Physical Health and Cognitive Function in Individuals With Intellectual Disabilities

2026年8月6日 更新者：University of Macau
Intellectual disability (ID) is a neurodevelopmental disorder accompanied by sedentary lifestyles, which worsens cognitive function and physical health. Short-duration high-frequency exercise snacks (ES) may be a feasible intervention for adults with ID. This randomized controlled crossover study aims to explore the acute effects of exercise snacks, conventional HIIT and daily routine control on cognitive function, stereotyped behaviors and prefrontal cortex activation in adults with mild to moderate ID. All participants will receive three intervention conditions with a 1-week washout period between each trial. Neurophysiological indicators including EEG and heart rate variability will be measured to reveal the underlying mechanisms.

研究概览

地位

尚未招聘

条件

干预/治疗

详细说明

Background:

Adults with intellectual disability commonly maintain sedentary daily routines, resulting in progressive decline in physical fitness and cognitive performance. Traditional long-duration exercise interventions are difficult to implement for this population due to behavioral and cognitive limitations. Exercise snacks, consisting of repeated ultra-short exercise bursts, are easy to carry out and show promising benefits for cognition.

Methods:

A randomized controlled crossover design will be adopted. Twenty-four adults aged 18-35 years with mild to moderate ID will complete three conditions in random sequence: no-exercise control, high-intensity interval training (HIIT), and exercise snacks (ES). A 1-week washout interval separates different interventions.

Intervention protocols:

  1. Control: maintain habitual daily activities.
  2. HIIT: one afternoon session, 10 sets of 6-second high-knee exercise with 9 seconds rest.
  3. ES: morning and afternoon sessions every day; each session contains 5 sets of 6-second high-knee exercise with 9 seconds rest.

Main measurements include prefrontal cortex activation via EEG, cognitive function, stereotyped behaviors, and heart rate variability. Repeated-measures statistical models will be used for data analysis.

研究类型

介入性

注册 (估计的)

24

阶段

  • 不适用

联系人和位置

本节提供了进行研究的人员的详细联系信息，以及有关进行该研究的地点的信息。

学习联系方式

  • 姓名：Yuping Zhou, master
  • 电话号码：+86-18811611796
  • 邮箱：yc57146@um.edu.mo

学习地点

  • 中国
    • Zhejiang
      • Hangzhou、Zhejiang、中国
        • Hangzhou First Social Welfare Institute
        • 接触：

参与标准

研究人员寻找符合特定描述的人，称为资格标准。这些标准的一些例子是一个人的一般健康状况或先前的治疗。

资格标准

适合学习的年龄

  • 成人

接受健康志愿者

不

描述

Inclusion Criteria:

  1. Aged 18-35 years old;
  2. Clinically diagnosed mild to moderate intellectual disability;
  3. Able to follow simple verbal instructions and complete exercise protocols;
  4. No contraindications for moderate physical activity confirmed by medical inquiry;
  5. Participants or legal guardians provide written informed consent;
  6. Maintain stable daily routine and do not participate in other structured exercise programs during the trial.

Exclusion Criteria:

  1. Severe physical disabilities, orthopedic injury or neurological disorders that restrict movement;
  2. History of cardiovascular disease, uncontrolled hypertension or other exercise contraindications;
  3. Current psychiatric medication that significantly affects motor or cognitive function;
  4. Inability to cooperate with EEG and physiological signal collection;
  5. Pregnancy;
  6. Participation in other interventional studies within the past 3 months.

学习计划

本节提供研究计划的详细信息，包括研究的设计方式和研究的衡量标准。

研究是如何设计的？

设计细节

  • 主要用途：基础科学
  • 分配：随机化
  • 介入模型：交叉作业
  • 屏蔽：无（打开标签）

武器和干预

参与者组/臂
干预/治疗
无干预：Arm 1
Participants maintain their usual daily activities without additional prescribed exercise. Daily physical activity will be recorded throughout the intervention period.
实验性的：Arm 2（Exercise Snacks）
Twice-daily short-bout exercise snacks. Each session includes 5 sets of 6-second high-knee exercise with 9 seconds rest between sets.
行为的：Exercise Snacks
Twice-daily short-bout exercise snacks. Each session includes 5 sets of 6-second high-knee exercise with 9 seconds rest between sets.
实验性的：Arm 3（High-Intensity Interval Training ）
One intervention session scheduled in the afternoon. The protocol consists of 10 sets of 6-second high-knee exercise, separated by 9 seconds of rest between sets.
行为的：High-Intensity Interval Training
Acute high-intensity interval training protocol: 10 × 6 s high-knee exercise with 9 s rest between sets, completed in a single afternoon session.

研究衡量的是什么？

主要结果指标

结果测量
措施说明
大体时间
Changes in cognitive function assessed by cognitive test battery
大体时间：Baseline and immediately after the acute intervention
Changes in cognitive performance measured after each intervention condition, including attention and executive function.
Baseline and immediately after the acute intervention

次要结果测量

结果测量
措施说明
大体时间
Prefrontal cortex activation measured by electroencephalography (EEG)
大体时间：Baseline and immediately after the acute intervention
Changes in prefrontal cortical brain activity indexed by EEG power spectrum during cognitive tasks.
Baseline and immediately after the acute intervention

合作者和调查者

在这里您可以找到参与这项研究的人员和组织。

赞助

University of Macau

调查人员

  • 首席研究员：Zhaowei Kong, PhD、University of Macau

研究记录日期

这些日期跟踪向 ClinicalTrials.gov 提交研究记录和摘要结果的进度。研究记录和报告的结果由国家医学图书馆 (NLM) 审查，以确保它们在发布到公共网站之前符合特定的质量控制标准。

研究主要日期

学习开始 (估计的)

2026年11月16日

初级完成 (估计的)

2027年1月18日

研究完成 (估计的)

2027年2月8日

研究注册日期

首次提交

2026年7月29日

首先提交符合 QC 标准的

2026年8月6日

首次发布 (实际的)

2026年8月12日

研究记录更新

最后更新发布 (实际的)

2026年8月12日

上次提交的符合 QC 标准的更新

2026年8月6日

最后验证

2026年7月1日

更多信息

与本研究相关的术语

关键字

其他相关的 MeSH 术语

其他研究编号

  • BSE-1553-2026

计划个人参与者数据 (IPD)

计划共享个人参与者数据 (IPD)？

是的

IPD 计划说明

De-identified individual participant data will be available upon reasonable request to the corresponding investigator after study completion and main publication. Data sharing will be subject to a formal data use agreement.

IPD 共享时间框架

Data and supporting materials will be available starting 6 months following the publication of primary study outcomes, and remain accessible for up to 5 years thereafter.

IPD 共享访问标准

Qualified researchers who submit a methodologically sound research proposal. Requests need to be sent to the corresponding investigator and a data use agreement must be signed.

IPD 共享支持信息类型

  • 研究方案
  • 树液
  • 国际碳纤维联合会
  • 分析代码

药物和器械信息、研究文件

研究美国 FDA 监管的药品

不

研究美国 FDA 监管的设备产品

不

此信息直接从 clinicaltrials.gov 网站检索，没有任何更改。如果您有任何更改、删除或更新研究详细信息的请求，请联系 register@clinicaltrials.gov. clinicaltrials.gov 上实施更改，我们的网站上也会自动更新.

订阅