Study of Cognitive-Linguistic Profiles: The Role of Executive Control in Aphasia (P-CLAC)
Study of Cognitive-linguistic Profiles in Brain-injured Adults: the Role of Executive Control in Mild Aphasia.
In France, stroke affects 150,000 people annually and is the leading cause of acquired disability in adults; 10-12% of patients exhibit mild post-stroke aphasia, a condition defined by language difficulties.
Few studies describe mild post-stroke aphasia, and none characterize the impairment of linguistic executive control in this population; consequently, its prevalence remains unknown. To date, the role of linguistic executive control in mild aphasia remains an open question.
The aim of this project is to investigate linguistic executive control impairment in stroke survivors with mild aphasia, provide an initial estimate of its prevalence, and demonstrate its interactions with other linguistic and communicative aspects, as well as with executive and attentional functions.
研究概览
研究类型
注册 (估计的)
阶段
- 不适用
联系人和位置
学习联系方式
- 姓名：Elodie GUILLOUET
- 电话号码：+33 0561779072
- 邮箱：guillouet.E@chu-toulouse.fr
学习地点
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Toulouse、法国、31300
- Service de Médecine Physique et de Réadaptation Hôpital Raymonde Fournet Purpan
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接触：
- Emeline Muller
- 电话号码：+33 0561778707
- 邮箱：muller.E@chu-toulouse.Fr
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参与标准
资格标准
适合学习的年龄
- 成人
- 年长者
接受健康志愿者
描述
Inclusion Criteria:
- Patient who has experienced a first ischemic stroke resulting in clinical symptoms within the last 3 months and is receiving care in the Physical Medicine and Rehabilitation department.
- Score ≤ 31 on the conversational speech observation scale of the MEC test (Montreal Protocol for the Evaluation of Communication).
- Patients with a BDAE score ≥ 3 (Boston Diagnostic Aphasia Examination - French version, Mazaux J.-M. [1990]); this score is the gold standard in aphasiology.
- Native French-speaking patient capable of understanding oral or written instructions.
Exclusion Criteria:
- Patients exhibiting behavior or a clinical condition incompatible with test administration, as assessed by the clinician.
- Known major visual, auditory, or motor impairments incompatible with test performance.
- Known neurodegenerative and/or neurodevelopmental disorders.
- Known social cognition disorders (e.g., ASD).
学习计划
研究是如何设计的？
设计细节
- 主要用途：预防
- 分配：不适用
- 介入模型：单组作业
- 屏蔽：无（打开标签）
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
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实验性的：Patients whose neuropsychological and speech-language pathology tests will be randomized
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Patients undergo neuropsychological tests, the order of which will be randomized.
Patients will undergo speech-language assessments, with the order of the tests randomized.
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研究衡量的是什么？
主要结果指标
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
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measure the proportion of patients with mild post-stroke aphasia exhibiting deficits in linguistic executive control within three months of a first stroke
大体时间：7 days after the inclusion
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CATEX score result (deficit score if below the mean value minus 1.65 times the standard deviation)
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7 days after the inclusion
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次要结果测量
结果测量 |
大体时间 |
|---|---|
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Study of the correlation between executive control of language (CATEX score) and the score of the test evaluating access to the lexical stock
大体时间：7 days after the inclusion
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7 days after the inclusion
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Study of the correlation between linguistic executive control (CATEX score) and the score of the test evaluating access to the semantic system
大体时间：7 days after the inclusion
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7 days after the inclusion
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Study of the correlation between linguistic executive control (CATEX score) and the score of the test evaluating non-verbal executive control
大体时间：7 days after the inclusion
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7 days after the inclusion
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Study of the correlation between linguistic executive control (CATEX score) and the score of the test evaluating gnosies
大体时间：7 days after the inclusion
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7 days after the inclusion
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Identification of patients' cognitive-linguistic impairment profiles based on cognitive test scores
大体时间：7 days after the inclusion
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7 days after the inclusion
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Identification of patients' cognitive-linguistic impairment profiles based on stroke location using factor analysis
大体时间：7 days after the inclusion
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7 days after the inclusion
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合作者和调查者
研究记录日期
研究主要日期
学习开始 (估计的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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