- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00243360
Optimizing Antibiotic Use in Long Term Care
October 21, 2005 updated by: Agency for Healthcare Research and Quality (AHRQ)
The purpose of this study was to determine if a multi-faceted intervention to implement diagnostic and therapeutic algorithms for management of suspected urinary infection in nursing home residents could reduce antibiotic prescribing for urinary indications in this population.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
Antibiotic use is intense in nursing homes and frequently inappropriate when prescribed for urinary indications.
Evidence from randomized controlled trials suggests that treatment of asymptomatic bacteriuria, the presence of bacteria in the urine in the absence of urinary symptoms, is not beneficial.
Despite this, one in three prescriptions for urinary indications are for asymptomatic bacteriuria.
To improve antibiotic prescribing in this setting we conducted a cluster randomized trial of a strategy to implement diagnostic and treatment algorithms for urinary infection.
24 nursing homes were randomized to either the intervention (implemented at the nursing home level using a multi-faceted approach: small group interactive sessions for nurses, one-on-one interviews for physicians, videotapes, written material, and outreach visits) or to usual care.
Study Type
Interventional
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Ontario
-
Hamilton, Ontario, Canada, L8N 3Z5
- McMaster University
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
1 second and older (Child, Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Individuals- all residents eligible
Nursing homes
- Free standing long term care facilities with >100 beds
- No stated policy for diagnosis or treatment of urinary tract infections
- The facility agrees to refrain from introducing new strategies for antibiotic utilization or clinical pathways during study
Exclusion Criteria:
-
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Educational/Counseling/Training
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
---|
Antimicrobial prescriptions
|
Secondary Outcome Measures
Outcome Measure |
---|
Urinary cultures,
|
hospitalizations, deaths
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
January 1, 2001
Study Completion
July 1, 2003
Study Registration Dates
First Submitted
October 21, 2005
First Submitted That Met QC Criteria
October 21, 2005
First Posted (Estimate)
October 24, 2005
Study Record Updates
Last Update Posted (Estimate)
October 24, 2005
Last Update Submitted That Met QC Criteria
October 21, 2005
Last Verified
October 1, 2005
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- U18HS011113-01 (U.S. AHRQ Grant/Contract)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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