Automated Chest Compression in Cardiac Arrest

July 14, 2009 updated by: Beaujon Hospital

Effect on Hemodynamics of Automated Band Chest Compression Device in Cardiac Arrest Resuscitation

To evaluate the effect of use of automated chest compression device on blood pressure in patients presenting with cardiac arrest. Higher systolic, diastolic and mean blood pressures are expected.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

The protocol compares arterial pressures produced by an automated self-adjusting load-distributing band device (AutoPulse™ 100, Zoll®) with those of manual cardiopulmonary resuscitation in refractory out-of-hospital cardiac arrest. Each patient will receive first manual compressions and then automated resuscitation.

Patients presenting with cardiac arrest are treated following standard advanced life support guidelines. They are intubated and ventilated, received epinephrine and defibrillation if appropriate. Manuel chest compressions are continued. An arterial catheter is placed to monitor hemodynamics continuously as we usually do in this case. Patients are included at this stage. Three blood pressure values (every 1 minutes) are recorded. Then, the automated band device is started up without any pause, following our procedure for refractory cardiac arrest. Three blood pressure values are recorded again, during automated cardiopulmonary resuscitation.

Study Type

Observational

Enrollment (Anticipated)

30

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • France
      • Clichy, France, 92110
        • Departement of Anesthesiology, Intensive Care and EMS, Beaujon University Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Probability Sample

Study Population

Patients aged > 18 with out-of-hospital cardiac arrest

Description

Inclusion Criteria:

  • Age ≥ 18
  • Refractory cardiac arrest

Exclusion Criteria:

  • Defective invasive arterial blood pressure monitoring

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Diastolic blood pressures produced by manual and then by automated chest compressions will be recorded for each patient
Time Frame: Instantaneously
Instantaneously

Secondary Outcome Measures

Outcome Measure
Time Frame
Systolic blood pressures produced by manual and then by automated chest compressions will be recorded for each patient
Time Frame: Instantaneously
Instantaneously
Mean blood pressures produced by manual and then by automated chest compressions will be recorded for each patient
Time Frame: Instantaneously
Instantaneously

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Beaujon Hospital

Investigators

  • Principal Investigator: Francois-Xavier Duchateau, MD, Departement of Anesthesiology, Intensive Care and EMS, Beaujon University Hospital
  • Study Chair: Jean Mantz, MDPhD, Departement of Anesthesiology, Intensive Care and EMS, Beaujon University Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

February 1, 2008

Primary Completion (Actual)

January 1, 2009

Study Completion (Actual)

January 1, 2009

Study Registration Dates

First Submitted

March 18, 2008

First Submitted That Met QC Criteria

March 18, 2008

First Posted (Estimate)

March 21, 2008

Study Record Updates

Last Update Posted (Estimate)

July 15, 2009

Last Update Submitted That Met QC Criteria

July 14, 2009

Last Verified

July 1, 2009

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • BAND V6

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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