- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01129947
The Use of DHEA in Women With Premature Ovarian Failure
January 26, 2013 updated by: Fady I. Sharara, M.D, Virginia Center for Reproductive Medicine
DHEA supplementation has been used in women with infertility and diminished ovarian reserve.
There is a small report in 5 women with POF that benefited from the use of DHEA over several months.
The investigators aim to evaluate further the use of DHEA in women with Premature ovarian failure (POF).
Study Overview
Study Type
Interventional
Phase
- Early Phase 1
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Virginia
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Reston, Virginia, United States, 20190
- Virginia Center for Reproductive Medicine
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 40 years (Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
Female
Description
Inclusion Criteria:
- women with POF
Exclusion Criteria:
- women without ovaries
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Non-Randomized
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: DHEA
|
DHEA 25 mg tid
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What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
The Use of DHEA in Women With Premature Ovarian Failure
Time Frame: 3 years
|
The following outcomes will be evaluated: FSH, AMH, estradiol, ovarian volume, antral follicle count, pregnancy in women seeking to conceive
|
3 years
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
May 1, 2010
Primary Completion (Actual)
January 1, 2013
Study Completion (Actual)
January 1, 2013
Study Registration Dates
First Submitted
May 23, 2010
First Submitted That Met QC Criteria
May 24, 2010
First Posted (Estimate)
May 25, 2010
Study Record Updates
Last Update Posted (Estimate)
January 29, 2013
Last Update Submitted That Met QC Criteria
January 26, 2013
Last Verified
January 1, 2013
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- VCRM4
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Premature Ovarian Failure
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Forever Young d.o.o.Medigroup Health System, Jevremova hospital; Saint James Hospital Malta; Re-medika...UnknownMenopause | Menopause, Premature | Premature Ovarian Failure | Ovarian Failure, Premature | Ovarian Failure | Ovarian Insufficiency | Ovarian Insufficiency, Primary | Premature Ovarian Failure 2A | Premature Ovarian Failure 3 | Premature Ovarian Failure 4 | Premature Ovarian Failure 1 | Premature Ovarian Failure... and other conditionsMalta, North Macedonia, Serbia
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Ascendance BiomedicalCompletedInfertility | Menopause | Menopause, Premature | Infertility, Female | Premature Ovarian Failure | Menopause Related Conditions | Perimenopausal Disorder | Infertility Unexplained | Menopause Premature Symptomatic | Menopause Premature Asymptomatic | Premature Ovarian Failure, Familial | Premature Ovarian Failure... and other conditionsUnited States
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Shenzhen Beike Bio-Technology Co., Ltd.UnknownPremature Ovarian Failure,China
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Assistance Publique - Hôpitaux de ParisNot yet recruitingPremature Ovarian Failure (POF)France
-
Instituto de Investigacion Sanitaria La FeUnknownPremature Ovarian Failure (POF)Spain
-
Assistance Publique - Hôpitaux de ParisCompletedFamilial Premature Ovarian FailureFrance
-
Genesis Athens ClinicNational and Kapodistrian University of AthensRecruitingMenopause, Premature | Menopausal Syndrome | Premature Ovarian Failure | Ovarian Failure, Premature | Menopause Related ConditionsGreece
-
UMC UtrechtUniversity Medical Center Groningen; Erasmus Medical Center; Catharina Ziekenhuis... and other collaboratorsUnknownPremature Ovarian Failure (POF) | Incipient Ovarian Failure | Poor Response After Ovarian Hyperstimulation | Early Menopause | Hypergonadotropic AmenorrheaNetherlands
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Equipo Juana CrespoUnknownIVF | Premature Ovarian Failure | Ovarian FailureSpain
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Acibadem UniversityCompletedPremature Ovarian Failure | Diminished Ovarian ReserveTurkey
Clinical Trials on DHEA
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EndoCeutics Inc.Completed
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Cairo UniversityCompleted
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National Institute on Aging (NIA)Completed
-
Shaare Zedek Medical CenterUnknownInfertility, Female | In-Vitro Fertilization
-
The University of Hong KongCompletedFemale Infertility Due to Diminished Ovarian ReserveHong Kong
-
National Center for Complementary and Integrative...Completed
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Mayo ClinicNational Institutes of Health (NIH); National Institute on Aging (NIA)Completed
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Mayo ClinicNational Institutes of Health (NIH); National Institute on Aging (NIA)CompletedAging | Dehydroepiandosterone Replacement | DHEA ReplacementUnited States
-
National Institute on Aging (NIA)Completed
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CHU de Quebec-Universite LavalCompleted