Clinical and Laboratory Characteristics of Patients Admitted With Syncope; Diagnosis and Follow up After These Patients

Observational Study Following After Patients Admitted With Syncope

The investigators hypothesis is that a significant number of patients may remain without specific cause and have recurrent syncope with its associated physical and mental morbidity.

Study Overview

• Status: Suspended
• Conditions: Recurrence; Diagnosis

Detailed Description

1. Patients with diagnosis of syncope who were admitted to the medical ward will be interviewed and their charts reviewed to rule in or out the diagnosis of syncope.
2. Assess physical and mental injury as a result of syncope.

3. The lab workup will be documented including;

   1. - Routine blood tests.

      • troponin level.

   2. - ECG.

      • Echocardiogram
      • Brain CT.
      • EEG.
      • U/S doppler of carotids.
      • Tilt tests.
4. At the time of diagnosis the final diagnosis will be documented including recommendations for patients to prevent syncope after discharge.
5. Follow up after patients by phone verifying recurrence of syncope and resulting physical and or mental injury if any.

• Study Type: Observational
• Enrollment (Anticipated): 40

Contacts and Locations

Study Locations

• Israel
  • Haifa, Israel, 34362
    • Department of Medicine, Carmel Medical Center

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Admitted patients the medical ward

Description

Inclusion Criteria:

• patients with diagnosis of syncope on admission to the medical ward.

Exclusion Criteria:

• patients with loss of consciousness due to other than low perfusion of the brain
• patients that can't sign a consent form
• patients that we can't get details about the episode of the syncope

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Only
• Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
diagnosis	Final diagnosis as a cause of syncope	1 year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
recurrence	how many patients had recurrence of syncope and average number of syncope in these patients during the period of follow up of each patient.	6 months
physical injury	During this period of follow up of each patient, was there a physical injury, graded either none, mild, moderate or severe (bedridden)	6 months
Mental effect	fear of recurrent syncope affecting his mobility and graded from mild to severe where severe indicates fear of moving even one step without support.	6 months

Collaborators and Investigators

• Sponsor: Carmel Medical Center
• Investigators: Principal Investigator: George S Habib, M.D., Carmel Medical Center

Study record dates

Study Major Dates

• Study Start: August 1, 2010
• Study Completion (Anticipated): June 1, 2011

Study Registration Dates

• First Submitted: August 17, 2010
• First Submitted That Met QC Criteria: September 14, 2010
• First Posted (Estimate): September 15, 2010

Study Record Updates

• Last Update Posted (Estimate): June 21, 2011
• Last Update Submitted That Met QC Criteria: June 19, 2011
• Last Verified: September 1, 2010

More Information

Terms related to this study

• Keywords: syncope; recurrence; evaluation; morbidity
• Additional Relevant MeSH Terms: Pathologic Processes; Nervous System Diseases; Neurologic Manifestations; Neurobehavioral Manifestations; Disease Attributes; Unconsciousness; Consciousness Disorders; Disease; Recurrence; Syncope
• Other Study ID Numbers: SYN2010