Specimen Stability Study

May 15, 2013 updated by: Astute Medical, Inc.

Urine Sample Processing Study:Analysis of Fresh Versus Frozen Urine Samples From Critically Ill Subjects

To collect and process urine samples from critically ill subjects for use in assessing the effects of various urine sample freezing and storage conditions on biomarker test results.

Study Overview

Status

Completed

Conditions

Study Type

Observational

Enrollment (Actual)

124

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

    • California
      • La Mesa, California, United States, 91942
    • Hawaii
      • Honolulu, Hawaii, United States, 96813
    • Idaho
      • Idaho Falls, Idaho, United States, 83404
    • Nevada
      • Las Vegas, Nevada, United States, 89109
    • New York
      • Port Jefferson, New York, United States, 11777
    • North Carolina
      • Greenville, North Carolina, United States, 27834

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

21 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Critically-ill adult subjects at risk for acute kidney injury.

Description

Inclusion Criteria:

  1. Males and females 21 years of age or older
  2. Subjects must be enrolled (first study-specific sample collection) within 24 hours of ICU admission

    • Subjects enrolled from ED or Floor must be admitted to the ICU within 24 hours of enrollment
    • Subjects enrolled in the ICU must have been admitted to the ICU or transferred into the study ICU from another ICU no more than 24 hours prior to enrollment
  3. Expected to remain in the ICU for at least 48 hours after enrollment
  4. Use of indwelling urinary catheter as standard care expected for at least 48 hours after enrollment
  5. Subject (or authorized representative)able and willing to provide written informed consent for study participation

Exclusion Criteria:

  1. Special populations including children, pregnant women, and prisoners
  2. Previous renal transplantation
  3. Already receiving dialysis (either acute or chronic) or in imminent need of dialysis at the time of enrollment
  4. Known infection with human immunodeficiency virus (HIV) or active hepatitis (acute or chronic)
  5. Subjects with a history of chronic kidney disease (CKD) without a baseline serum creatinine value (baseline within 6 months of enrollment)
  6. Previously provided a urine sample and enrolled in this study

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Specimen handling and stability, for example, effect of temperature on biomarker results. There are no primary clinical outcomes.
Time Frame: 6 months
6 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

November 1, 2012

Primary Completion (Actual)

May 1, 2013

Study Completion (Actual)

May 1, 2013

Study Registration Dates

First Submitted

April 29, 2013

First Submitted That Met QC Criteria

May 1, 2013

First Posted (Estimate)

May 6, 2013

Study Record Updates

Last Update Posted (Estimate)

May 17, 2013

Last Update Submitted That Met QC Criteria

May 15, 2013

Last Verified

May 1, 2013

More Information

Terms related to this study

Other Study ID Numbers

  • Opal

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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