Study of the Long-term Effects of Exercise on Heath Indicators in Older People

March 24, 2017 updated by: Nelson Joaquim Fortuna de Sousa, University of Trás-os-Montes and Alto Douro

A Randomised Longitudinal Study of Exercise Prescription for Older Adults: Mode and Intensity to Induce the Highest Cardiovascular Health-related Benefits

Cardiovascular diseases (CVD) represent the most frequent cause of death among the elderly population. Hypertension, unfavorable lipid profile, obesity and physical inactivity are among the main risk factors for CVD. In contrast, mortality from CVD is inversely related to levels of physical activity, and is lower in individuals who exercise and have higher functional fitness levels. Thus, the Centers for Disease Control and Prevention, the American College of Sports Medicine, and the American Heart Association have recommended 20-30 min of moderate-to-vigorous aerobic training for the elderly, preferably every day or at least 3 days a week in the case of vigorous exercise.The same organizations also suggest the inclusion of resistance training in order to improve functional fitness. Therefore, the purpose of this study was to compare different exercise modalities in long-term changes of CVD risk factors and physical fitness among older adults.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

66

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Portugal
      • Maia, Portugal, 4470-384
        • Maia City Council facilities

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

65 years to 79 years (Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  • Older adults living independently;
  • medical approval.

Exclusion Criteria:

  • Non-smokers;
  • Non-morbidly obese;
  • No history of severe hypertension;
  • No history of falls;
  • No orthopaedic, neurological, pulmonary, or cardiac problems.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Aerobic exercise training
Dose response
Behavioral: Exercise training
Both training programs were of moderate-to-vigorous intensity, three days per week for nine months.
Other Names:
  • resistance training
  • Aerobic training
  • Combined training
  • multicomponent training
Experimental: Aerobic and resistance exercise training
Dose response
Behavioral: Exercise training
Both training programs were of moderate-to-vigorous intensity, three days per week for nine months.
Other Names:
  • resistance training
  • Aerobic training
  • Combined training
  • multicomponent training
No Intervention: Control
Non-exercising control group

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Cardiovascular Disease Risk Factors
Time Frame: one year
Descriptive frequency of the number of cardiovascular risk factors aggregated in each participant. The risk factors considered were: (i) hypertension; (ii) obesity; and (iii) dyslipidemia.
one year

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Risk of Falls
Time Frame: One year
Descriptive frequency of the number of participants who took ≥12 seconds to complete the Timed Get-up and Go test, and those who took less than 12 seconds (low risk of falling).
One year

Other Outcome Measures

Outcome Measure
Measure Description
Time Frame
Quality of Life
Time Frame: One year
Measured by the Satisfaction With Life Scale.
One year

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Trás-os-Montes and Alto Douro

Investigators

  • Principal Investigator: Nelson Sousa, PhD, Research Center in Sport Sciences, Health Sciences and Human Development; University of Trás-os-Montes e Alto Douro
  • Study Director: José Oliveira, PhD, Research Center in Physical Activity, Health and Leisure; Sport Faculty, University of Porto
  • Study Chair: Romeu Mendes, MD, University of Trás-os-Montes and Alto Douro

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

May 1, 2011

Primary Completion (Actual)

September 1, 2011

Study Completion (Actual)

September 1, 2014

Study Registration Dates

First Submitted

June 6, 2013

First Submitted That Met QC Criteria

June 6, 2013

First Posted (Estimate)

June 10, 2013

Study Record Updates

Last Update Posted (Actual)

May 8, 2017

Last Update Submitted That Met QC Criteria

March 24, 2017

Last Verified

March 1, 2017

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • CVD-2009-EX

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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