Effect of Ginseng on Blood Pressure

Effect of Ginseng on Blood Pressure: A Systematic Review and Meta-Analysis of Controlled Trials

To determine the effect of ginseng on blood pressure control.

Study Overview

• Status: Completed
• Conditions: Blood Pressure
• Intervention / Treatment: Dietary supplement: Ginseng

Detailed Description

The effect of ginseng on blood pressure control is controversial, originating from an early 1970s observational study, suggesting that ginseng may adversely effect blood pressure. Despite these early findings, extensive research has since suggested that ginseng may have a positive effect on blood pressure. The current study will help clarify present uncertainty on the effect of ginseng on blood pressure control.

This systematic review and meta-analysis will follow The Cochrane Handbook for Systematic Reviews of Interventions. MEDLINE, EMBASE, CINAHL and The Cochrane Central Register of Controlled Trials will be searched using appropriate search terms. Intervention trials that investigate the effect of ginseng on blood pressure in humans will be included.

• Study Type: Observational
• Enrollment (Anticipated): 500

Contacts and Locations

Study Locations

• Canada
  • Ontario
    • Toronto, Ontario, Canada, M5C 2T2
      • The Toronto 3D Knowledge Synthesis and Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: ADULT; OLDER_ADULT; CHILD
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Hypertensive Healthy

Description

Inclusion Criteria:

• clinical trials in humans
• randomized treatment allocation
• ≥ 1 month
• suitable control
• viable endpoint data

Exclusion Criteria:

• non-human studies
• non-randomized treatment allocation
• < 1 month
• lack of a suitable control
• no viable endpoint data
• trials where ginseng is part of a multi-herbal treatment

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Systolic Blood Pressure	1 month

Secondary Outcome Measures

Outcome Measure	Time Frame
Diastolic Blood Pressure	1 month
Mean Arterial Pressure	1 month

Collaborators and Investigators

• Sponsor: Unity Health Toronto
• Investigators: Study Director: Allison Komishon, MSc(c), Unity Health Toronto

Study record dates

Study Major Dates

• Study Start: April 1, 2013
• Primary Completion (ACTUAL): May 1, 2013
• Study Completion (ACTUAL): January 1, 2016

Study Registration Dates

• First Submitted: July 29, 2013
• First Submitted That Met QC Criteria: July 29, 2013
• First Posted (ESTIMATE): July 31, 2013

Study Record Updates

• Last Update Posted (ESTIMATE): March 3, 2016
• Last Update Submitted That Met QC Criteria: March 2, 2016
• Last Verified: March 1, 2016

More Information

Terms related to this study

• Other Study ID Numbers: MetaBPG