- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02583750
Snooze Control: Sleep Duration & Glucose Metabolism
October 20, 2015 updated by: Xuewen Wang
Snooze Control: The Effect of Sleep Deprivation on Glucose Metabolism
This project investigated how glucose metabolism differs due to sleep deprivation for three consecutive nights as compared to sufficient sleep for three nights by examining concentrations of glucose, insulin, and other factors involved in glucose metabolism.
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
16 participants were enrolled in the study (8 females, 8 males) aged 18-25 years.
In order for the participants to qualify for the study, each had to wear a pedometer for a week before the study began to determine eligibility.
Each participant came to the lab for an oral glucose tolerance test on a morning, following three nights when they were sleep deprived, and on another morning when they had three nights' sufficient sleep.
The sequence of the oral glucose tolerance tests were randomly assigned.
The sleep duration for participants was monitored by the readings of the sleep monitors that each participant wore.
The oral glucose tolerance tests were performed after an overnight fast.
A 20-gauge polyethylene catheter was placed in the antecubital vein for blood sampling.
Blood samples were drawn once (0 min) before and 4 times (30, 60, 90, and 120 min) after a 75g glucose drink was consumed for the determination of plasma glucose, insulin, and concentrations of other factors.
Each participant was told to continue their regular routine during the study period, including diet, caffeine usage, and exercise.
Study Type
Interventional
Enrollment (Actual)
16
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
South Carolina
-
Columbia, South Carolina, United States, 29201
- Public Health Research Center University of South Carolina
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 25 years (Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Description
Inclusion Criteria:
- healthy college-aged males and females
- being minimally active
Exclusion Criteria:
- average more than 15,000 steps a day
- major health issues such as heart disease, diabetes
- taking medication to help with sleep or using a sleeping device
- any type of sleep problem such as sleep apnea
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Health Services Research
- Allocation: Non-Randomized
- Interventional Model: Crossover Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: OGTT after deprived sleep first
Participants came to the lab to perform the oral glucose tolerance test after three nights of sleep deprivation, then another test after three nights of sufficient sleep
|
Participants slept 1-3 hours less than their normal amount for three nights, and then came to the lab for the oral glucose tolerance testing after a 12 hour overnight fast.
The second oral glucose tolerance test was after they slept as much as they wanted for three nights.
|
Experimental: OGTT after sufficient sleep first
Participants came to the lab to perform the oral glucose tolerance test after three nights of sufficient sleep, then another test after three nights of deprived sleep
|
Participants slept as much as they wanted for three nights, and then came to the lab for the oral glucose tolerance testing after a 12 hour overnight fast.
The second oral glucose tolerance test was after they slept 1-3 hours less than normal for three nights.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Glucose concentrations during oral glucose tolerance test
Time Frame: two hours
|
two hours
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Xuewen Wang, PhD, University of South Carolina
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
January 1, 2014
Primary Completion (Actual)
August 1, 2014
Study Completion (Actual)
September 1, 2014
Study Registration Dates
First Submitted
October 15, 2015
First Submitted That Met QC Criteria
October 20, 2015
First Posted (Estimate)
October 22, 2015
Study Record Updates
Last Update Posted (Estimate)
October 22, 2015
Last Update Submitted That Met QC Criteria
October 20, 2015
Last Verified
October 1, 2015
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- Pro00032421
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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