National Health and Nutrition Examination Survey 24-hour Urine Collection Feasibility Study, 2013

National Health and Nutrition Examination Survey 24-Hour Urine Collection Feasibility Study, 2013

A 24-hour urine pilot study was conducted as part of the 2013 NHANES to test the feasibility of implementing a 24-hour urine collection as part of NHANES in 2014.

Study Overview

• Status: Completed
• Conditions: Hypertension
• Intervention / Treatment: Other: Collect 24-hour urine specimen

Detailed Description

The 24-hour urine pilot study was conducted March - June 2013 in three NHANES locations. A random half-sample of non-pregnant US adults, aged 20-69 who were examined in the NHANES mobile examination center were selected. Participants received instructions, started and ended the urine collection in a urine study mobile examination center (UMEC), and answered questions about collection. A random half of participants who collected a complete 24-h urine were asked to collect a second 24-h urine. Urinary sodium, potassium, chloride, and creatinine excretion were analyzed.

Participation rates in two other post-examination components, the Physical Activity Monitor and the Dietary Recall, were monitored to determine whether collecting a 24-hour urine had an effect on response rates for the two components.

• Study Type: Observational
• Enrollment (Actual): 282

Contacts and Locations

Study Locations

• United States
  • Maryland
    • Hyattsville, Maryland, United States, 20782
      • National Health and Nutrition Examination Survey

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years to 69 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

NHANES participants aged 20-69 years who were examined in the mobile examination center.

Description

Inclusion Criteria:

• 20-69 year old adults examined in the NHANES mobile examination center

Exclusion Criteria:

• pregnant, unable to respond for themselves

Study Plan

How is the study designed?

Design Details

• Time Perspectives: Cross-Sectional

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Study completion rates - initial collection	Completion rate of initial 24-hour urine collection.	24 hours
Study completion rate - second collection	Completion rate of second 24-hour urine collection	24 hours

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Response rates for the Physical Activity Monitor	Response rates for the Physical Activity Monitor	24-hours
Response rates for the Phone Follow-up Dietary Recall	Response rates for the Phone Follow-up Dietary Recall.	24-hours
Urine volume for the initial urine collection	Urine volume adjusted to 24 hours, initial urine collection	24 hours
Urine volume for the second urine collection	Urine volume adjusted to 24 hours, second urine collection	24 hours
Urinary sodium excretion for the initial urine collection	24-hour urinary sodium excretion, initial urine collection	24 hours
Urinary sodium excretion for the second urine collection	24-hour urinary sodium excretion, second urine collection	24 hours

Collaborators and Investigators

• Sponsor: Centers for Disease Control and Prevention
• Collaborators: National Heart, Lung, and Blood Institute (NHLBI)
• Investigators: Study Director: Kathryn Porter, MD, MS, Centers for Disease Control and Prevention, National Center for Health Statistics, Division of Health and Nutrition Examination Surveys

Publications and helpful links

General Publications

• Terry AL, Cogswell ME, Wang CY, Chen TC, Loria CM, Wright JD, Zhang X, Lacher DA, Merritt RK, Bowman BA. Feasibility of collecting 24-h urine to monitor sodium intake in the National Health and Nutrition Examination Survey. Am J Clin Nutr. 2016 Aug;104(2):480-8. doi: 10.3945/ajcn.115.121954. Epub 2016 Jul 13.

Study record dates

Study Major Dates

• Study Start: March 1, 2013
• Primary Completion (Actual): June 1, 2013
• Study Completion (Actual): June 1, 2013

Study Registration Dates

• First Submitted: March 8, 2016
• First Submitted That Met QC Criteria: March 24, 2016
• First Posted (Estimate): March 30, 2016

Study Record Updates

• Last Update Posted (Estimate): March 30, 2016
• Last Update Submitted That Met QC Criteria: March 24, 2016
• Last Verified: March 1, 2016

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Cardiovascular Diseases; Vascular Diseases; Hypertension
• Other Study ID Numbers: 2011-17

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No
• IPD Plan Description: The NHANES 24-hour urine pilot study data set can be made available through the National Center for Health Statistics Research Data Center by submitting a research proposal at http://www.cdc.gov/rdc/.