- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03020355
Comparison of Blood Loss in Using vs Not Using Placental Cord Drainage After Spontaneous Vaginal Delivery
Study Overview
Status
Conditions
Intervention / Treatment
Detailed Description
The patients will prospectively randomized equally into two groups (100 each in the study and control groups).
Group-A (Study group)-Placental blood was drained.
Group-B (Control group)-Placental blood was not drained.
In all the patients detailed medical and obstetric history will taken. In each patient, the pre-delivery pulse rate, blood pressure, and Hb gm% will noted. Immediately after vaginal delivery, after clamping and cutting the cord-the cord will unclamped and the blood will drained until the flow ceased. In the control group, the clamped cord will not released. Blood lost in the third stage of labour will measured by collecting the blood measuring bag.
Study Type
Enrollment (Anticipated)
Phase
- Not Applicable
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Description
Inclusion Criteria:
- Singleton pregnancy
- Vertex presentation
- Gestational age of 37 weeks (or) more
- No major medical (or) obstetric complications
- Spontaneous vaginal delivery
Exclusion Criteria:
- Hb\7 gm/dl
- History of APH
- Instrumental delivery
- Multiple pregnancy
- Malpresentations
- Large baby (more than 3.5 kg)
- Polyhydramnios
- Known coagulations disorders
- Previous surgeries on the uterus
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Placental Blood Drainage
Immediately after vaginal delivery, after clamping and cutting the cord-the cord will unclamped and the blood will drained until the flow ceased.
|
Immediately after vaginal delivery, after clamping and cutting the cord-the cord will unclamped and the blood will drained until the flow ceased.
|
Active Comparator: not Placental Blood Drainage
In the control group, the clamped cord will not released.
|
In the control group, the clamped cord will not released.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Blood lost
Time Frame: through delivery completion, an average of 30 minutes
|
through delivery completion, an average of 30 minutes
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
The duration of the third stage
Time Frame: through the duration of the third stage, an average 45 minutes
|
The duration of the third stage will calculated using a stop watch.
|
through the duration of the third stage, an average 45 minutes
|
Collaborators and Investigators
Publications and helpful links
General Publications
- Roy P, Sujatha MS, Bhandiwad A, Biswas B, Chatterjee A. Placental Blood Drainage as a Part of Active Management of Third Stage of Labour After Spontaneous Vaginal Delivery. J Obstet Gynaecol India. 2016 Oct;66(Suppl 1):242-5. doi: 10.1007/s13224-016-0857-3. Epub 2016 Mar 12.
- Soltani H, Poulose TA, Hutchon DR. Placental cord drainage after vaginal delivery as part of the management of the third stage of labour. Cochrane Database Syst Rev. 2011 Sep 7;2011(9):CD004665. doi: 10.1002/14651858.CD004665.pub3.
Study record dates
Study Major Dates
Study Start
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 167
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Placental Blood Drainage
-
Guangdong Provincial People's HospitalUnknown
-
Maisonneuve-Rosemont HospitalUniversité de MontréalCompletedPlacental OxygenationCanada
-
Fundacion para la Salud Materno InfantilCompleted
-
Peking Union Medical College HospitalPeking University First Hospital; Cancer Institute and Hospital, Chinese Academy... and other collaboratorsCompletedDrainage | PancreaticoduodenectomyChina
-
Anup Katheria, M.D.CompletedPlacental TransfusionUnited States
-
Fundacion para la Salud Materno InfantilTerminated
-
Rheon Medical SAActive, not recruiting
-
AdministrateurCICCompleted
-
Policlinico Abano TermeCompletedPlacental Transfusion | Hematocrit AnemiaItaly
-
Dr. Elisabeth WüringerCompletedLymph Drainage of BreastAustria
Clinical Trials on Placental Blood Drainage
-
University of TennesseeSponsor GmbHCompleted
-
Zeynep Kamil Maternity and Pediatric Research and...Completed
-
Instituto Materno Infantil Prof. Fernando FigueiraCompletedManagement of DeliveryBrazil
-
Istanbul Bakirkoy Maternity and Children Diseases...CompletedPostpartum HaemorrhageTurkey
-
Ain Shams UniversityUnknown
-
Weill Medical College of Cornell UniversityCompletedPremature Birth of Newborn | Infant, Very Low Birth Weight | Placental Transfusion | Delayed Separation of Umbilical CordUnited States
-
Murdoch Childrens Research InstituteCompletedHeart Defects, Congenital | Hypoplastic Left Heart Syndrome | Pediatric DisorderAustralia
-
Centese, Inc.Stanford UniversityCompleted
-
Lester E. Cox Medical CentersCompleted
-
Chang Gung Memorial HospitalCompletedPregnancy Related | Placental Transfusion | Umbilical Cord IssueTaiwan