- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT03037840
Detecting Tumor Specific Amplitude-modulated Frequencies of Cancer Patients
October 11, 2018 updated by: Sherman Xuegang Xin, Southern Medical University, China
Detecting Tumor Specific Amplitude-modulated Frequencies of Cancer Patients In Vivo
Studies have shown that tumor specific amplitude-modulated frequencies of radiofrequency electromagnetic fields that is associated with biofeedback upon exposure to in cancer patients.
However, such discovery in other cancer patients are rare.
And whether tumor specific frequencies can be found in Asian cancer patients remains unclear.
The purpose of this study is to detect the tumor specific frequencies of Asian cancer patients in vivo.
Study Overview
Status
Unknown
Conditions
Intervention / Treatment
Detailed Description
The measurements were safety guaranteed and were conducted in hospital.
Before detecting, the patient will be already diagnosed with cancer.
The doctor and the operator are responsible for the detecting.
When cancer patients are exposure to the RF electromagnetic fields, the radial pulse amplitude, blood pressure, skin electrical resistance and breath will be monitored.
Biofeedback parameters will be recorded at different modulation frequencies and analyzed in order to find the variation and tumor specific frequencies.
Study Type
Observational
Enrollment (Anticipated)
200
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Xin Sherman Xuegang, professor
- Phone Number: 008613602733465
- Email: xxg@smu.edu.cn
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
- The patients who are diagnosed with cancer disease
- Healthy participators
Description
Inclusion Criteria:
- Clinical diagnosis of cancer Disease
Exclusion Criteria:
- other patients
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
cancer patients
Low intensity amplitude-modulated RF EMFs
|
Low intensity amplitude-modulated radiofrequency electromagnetic fields,the carrier frequency is 27.12MHz with a power of about 100mW
Other Names:
|
healthy participators
Low intensity amplitude-modulated RF EMFs
|
Low intensity amplitude-modulated radiofrequency electromagnetic fields,the carrier frequency is 27.12MHz with a power of about 100mW
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Biofeedback response of cancer patients at the exposure of Low intensity amplitude-modulated radiofrequency electromagnetic fields
Time Frame: within 20 min of exposure
|
within 20 min of exposure
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Representation of autonomous response during the exposure of tumor specific frequencies modutated RF eletromagnetic fields
Time Frame: within 20 min of exposure
|
within 20 min of exposure
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Collaborators
Investigators
- Principal Investigator: Xin Sherman Xuegang, professor, School of Biomedical Engineering,Southern Medical University
- Study Director: Cai Linbo, master, Guangdong 999 Brain Hospital
- Study Director: Zhu Xiaoxia, PhD, Nanfang Hospital of Southern Medical University
- Study Director: Liu Xiantang, bachelor, The 157th Hospital of PLA
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Barbault A, Costa FP, Bottger B, Munden RF, Bomholt F, Kuster N, Pasche B. Amplitude-modulated electromagnetic fields for the treatment of cancer: discovery of tumor-specific frequencies and assessment of a novel therapeutic approach. J Exp Clin Cancer Res. 2009 Apr 14;28(1):51. doi: 10.1186/1756-9966-28-51.
- Costa FP, de Oliveira AC, Meirelles R, Machado MC, Zanesco T, Surjan R, Chammas MC, de Souza Rocha M, Morgan D, Cantor A, Zimmerman J, Brezovich I, Kuster N, Barbault A, Pasche B. Treatment of advanced hepatocellular carcinoma with very low levels of amplitude-modulated electromagnetic fields. Br J Cancer. 2011 Aug 23;105(5):640-8. doi: 10.1038/bjc.2011.292. Epub 2011 Aug 9.
- Zimmerman JW, Pennison MJ, Brezovich I, Yi N, Yang CT, Ramaker R, Absher D, Myers RM, Kuster N, Costa FP, Barbault A, Pasche B. Cancer cell proliferation is inhibited by specific modulation frequencies. Br J Cancer. 2012 Jan 17;106(2):307-13. doi: 10.1038/bjc.2011.523. Epub 2011 Dec 1.
- Zimmerman JW, Jimenez H, Pennison MJ, Brezovich I, Morgan D, Mudry A, Costa FP, Barbault A, Pasche B. Targeted treatment of cancer with radiofrequency electromagnetic fields amplitude-modulated at tumor-specific frequencies. Chin J Cancer. 2013 Nov;32(11):573-81. doi: 10.5732/cjc.013.10177.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Anticipated)
December 1, 2018
Primary Completion (Anticipated)
June 1, 2019
Study Completion (Anticipated)
June 1, 2020
Study Registration Dates
First Submitted
July 6, 2016
First Submitted That Met QC Criteria
July 6, 2016
First Posted (Estimate)
January 31, 2017
Study Record Updates
Last Update Posted (Actual)
October 12, 2018
Last Update Submitted That Met QC Criteria
October 11, 2018
Last Verified
October 1, 2018
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- SXXin-AM-RF-EMF-in vivo
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
UNDECIDED
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Neoplasms
-
GlaxoSmithKlineCompleted
-
Amphia HospitalRecruitingColonic Neoplasms MalignantNetherlands
-
European Association for Endoscopic SurgeryWithdrawn
-
Marquette General Health SystemUpper Michigan Brain Tumor CenterWithdrawnGlioma | MeningiomaUnited States
-
Moscow Clinical Scientific CenterRecruitingCecal Neoplasms | Colonic Neoplasms MalignantRussian Federation
-
Ann & Robert H Lurie Children's Hospital of ChicagoCompletedBrain Stem Neoplasms, Primary | Neoplasms, Brain StemUnited States
-
GlaxoSmithKlineRecruitingNeoplasms, RectalUnited States, France, Italy, Japan, Spain, United Kingdom, Germany, Korea, Republic of, Canada, Netherlands
-
Russian Society of Colorectal SurgeonsRecruitingNeoplasms,ColorectalRussian Federation
-
Third Affiliated Hospital, Sun Yat-Sen UniversityRecruiting
-
Novartis PharmaceuticalsBayerCompletedColorectal Neoplasms | Rectal Neoplasms | Colonic NeoplasmsUnited States, Germany, Belgium, Canada, Spain, United Kingdom, Taiwan, France, Switzerland, Sweden, Portugal, New Zealand, Italy, Slovakia, Australia, Austria, Brazil, Hong Kong
Clinical Trials on Low intensity amplitude-modulated RF EMFs
-
Pasche, Boris, M.D.Barbault, Alexandre, M.S.CompletedCancer | Brain TumorSwitzerland
-
Hospital Sirio-LibanesCompletedHepatitis | Hepatocellular CarcinomasBrazil
-
NRG OncologyNational Cancer Institute (NCI)SuspendedProstate Adenocarcinoma | Stage IIIA Prostate Cancer AJCC v8 | Stage IIIB Prostate Cancer AJCC v8 | Stage IIC Prostate Cancer AJCC v8 | Stage III Prostate Cancer AJCC v8 | Stage IIIC Prostate Cancer AJCC v8 | Stage IVA Prostate Cancer AJCC v8Canada, United States
-
Radiation Therapy Oncology GroupNational Cancer Institute (NCI); NRG OncologyTerminatedPancreatic Adenocarcinoma | Stage III Pancreatic CancerUnited States
-
Galera Therapeutics, Inc.CompletedRadiation Induced Oral MucositisUnited States, Canada, Puerto Rico
-
Albert Einstein College of MedicineNational Cancer Institute (NCI)TerminatedUterine Carcinosarcoma | Stage IIA Uterine Sarcoma | Stage IIB Uterine Sarcoma | Stage IIIA Uterine Sarcoma | Stage IIIB Uterine Sarcoma | Stage IIIC Uterine Sarcoma | Stage IVA Uterine Sarcoma | Stage IVB Uterine Sarcoma | Stage IA Uterine Sarcoma | Stage IB Uterine Sarcoma | Stage IC Uterine SarcomaUnited States
-
Sun Yat-sen UniversityRecruitingNasopharyngeal Carcinoma | Chemotherapy | Radiotherapy | Immune Checkpoint InhibitorChina
-
Myovant Sciences GmbHCompletedUterine Fibroid | Heavy Menstrual BleedingUnited States, Italy, Poland, Brazil, South Africa, United Kingdom