Electromagnetic Field Effects of Mobile Communication (LTE) on Sleep in the Context of Genetic Variation

The effect of electromagnetic fields of the latest standard in mobile communication (long term evolution, LTE) on sleep is studied in healthy, young individuals.

Study Overview

• Status: Completed
• Conditions: Sleep
• Intervention / Treatment: Other: LTE field; Other: sham field

• Study Type: Interventional
• Enrollment (Actual): 34
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Switzerland
  • Zurich, Switzerland, 8057
    • University of Zurich, Institute of Pharmacology and Toxicology

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 30 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• Age 18-30 years
• German knowledge (reading and writing)
• Right-handedness
• Body mass index (BMI) 18.5-25.0 kg/m2
• Mobile communication (phone calls) less than 2 hours per week
• Moderate alcohol consumption (less than 5 alcoholic beverages per week)
• Moderate caffeine consumption (less than 5 caffeinated foods per day, e.g. coke, coffee, energy drinks, green or black tea, chocolate)
• Informed consent

Exclusion Criteria:

• Travels across more than 2 time zones in the last 30 days or during the study
• Nocturnal shift work
• Extreme chronotype or extreme sleep duration (less than 5 hours or more than 10 hours on average)
• Sleep disorders or problems
• Severe acute or chronic neurological, mental or general health disorders, which might impair the participant's safety or affect the study's outcome
• Use of medication (regular or during the study), which might affect the study's outcome
• Recreational drug use
• Smoking (or other tobacco products)
• Severe skin allergies
• Relevant findings in physical examination or during the screening night (e.g. sleep disorders)
• Participation in an other clinical trial in the last 30 days or during the study

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Basic Science
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: Quadruple

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: LTE field	Other: LTE field; electromagnetic field of the latest standard in mobile communication (long term evolution, LTE)
Sham Comparator: sham field	Other: sham field; no electromagnetic field

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
electroencephalographic power during sleep after LTE exposure	electroencephalogram (EEG)	up to 9 hours (approximately 11 p.m. to 8 a.m.)

Collaborators and Investigators

• Sponsor: University of Zurich
• Investigators: Principal Investigator: Hans-Peter Landolt, University of Zurich, Institute of Pharmacology and Toxicology

Study record dates

Study Major Dates

• Study Start (Actual): January 31, 2017
• Primary Completion (Actual): September 30, 2022
• Study Completion (Actual): September 30, 2022

Study Registration Dates

• First Submitted: February 23, 2017
• First Submitted That Met QC Criteria: March 3, 2017
• First Posted (Actual): March 9, 2017

Study Record Updates

• Last Update Posted (Estimate): January 30, 2023
• Last Update Submitted That Met QC Criteria: January 27, 2023
• Last Verified: January 1, 2023

More Information

Terms related to this study

• Other Study ID Numbers: LTE-Sleep

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No