Effects of Whole Body Vibration on Autonomic Function in Healthy Young and Elderly

Acute Effects of Whole Body Vibration on Autonomic Function in Healthy Young and Elderly

Aging causes anatomical and physiological changes in the cardiovascular system and autonomic function with decline in its maximum function. This study aimed to evaluate the acute effects of whole body vibration on cardiovascular system, autonomic function and heart variability in healthy young and elderly. The investigators' hypothesis is that whole body vibration has different effects in young and elderly.

Study Overview

• Status: Completed
• Conditions: Healthy; Aging
• Intervention / Treatment: Other: Whole Body Vibration

• Study Type: Interventional
• Enrollment (Actual): 35
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Brazil
  • Pernambuco
    • Recife, Pernambuco, Brazil
      • Federal University of Pernambuco

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 80 years (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Elderly individuals aged between 60 and 80 years
• Young individuals aged between 18 and 30 years
• Able to walk without assistance
• Good understanding to perform the proposed procedures
• Sedentary or low active

Exclusion Criteria:

• Body Mass Index (BMI) > 35Kg/m2
• Systolic blood pressure > 140 mmHg or diastolic blood pressure > 90 mmHg (at rest)
• Difficulty adapting to the whole body vibration
• Smoking
• Neuromuscular or degenerative disorders
• Neurological diseases
• Cardiopulmonary comorbidities
• Cardiac arrhythmias
• Osteoarticular disorders
• Use of hormone replacement therapy
• Use medications or supplements known to affect cardiovascular parameters
• Labyrinthitis

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Non-Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Young Group; Healthy young of both sexes between the ages of 18 and 30 years will perform a whole body vibration session	Other: Whole Body Vibration; A whole body vibration session will be performed through a vibrating platform with three axes and vibration frequency set at 35 Hz. The amplitude used will be 04 mm.
Experimental: Elderly Group; Healthy elderly of both sexes between the ages of 60 and 80 years will perform a whole body vibration session	Other: Whole Body Vibration; A whole body vibration session will be performed through a vibrating platform with three axes and vibration frequency set at 35 Hz. The amplitude used will be 04 mm.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Autonomic Function	Heart rate variability will be assessed from 3-channel holter	Change from Baseline Heart rate variability at 5, 10, 15, 20 and 35 minutes

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Sympathetic modulation	Sympathetic modulation will be assessed from 3-channel holter	Change from Baseline Sympathetic modulation at 5, 10, 15, 20 and 35 minutes
Parasympathetic modulation	Parasympathetic modulation will be assessed from 3-channel holter	Change from Baseline Parasympathetic modulation at 5, 10, 15, 20 and 35 minutes
Sympathovagal Balance	Sympathovagal Balance will be assessed from 3-channel holter	Change from Baseline Sympathovagal balance at 5, 10, 15, 20 and 35 minutes
Heart Rate	Non-invasive measures will be assessed from 3-channel holter	Change from Baseline Heart Rate at 5, 10, 15, 20 and 35 minutes
Blood pressure	Non-invasive measures of brachial blood pressure	Change from Baseline Blood pressure at 5, 10, 15, 20 and 35 minutes
Peripheral oxygen saturation	Non-invasive measures will be assessed from pulse oximeter	Change from Baseline Peripheral oxygen saturation at 5, 10, 15, 20 and 35 minutes
Adverse effects	Adverse effects reported by volunteers	Change from Baseline at 20 minutes

Collaborators and Investigators

• Sponsor: Universidade Federal de Pernambuco

Study record dates

Study Major Dates

• Study Start (Actual): July 31, 2017
• Primary Completion (Actual): August 31, 2017
• Study Completion (Actual): December 30, 2017

Study Registration Dates

• First Submitted: March 21, 2017
• First Submitted That Met QC Criteria: June 6, 2017
• First Posted (Actual): June 8, 2017

Study Record Updates

• Last Update Posted (Actual): January 3, 2018
• Last Update Submitted That Met QC Criteria: December 29, 2017
• Last Verified: December 1, 2017

More Information

Terms related to this study

• Other Study ID Numbers: WBV on autonomic function

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No