The Effects of Whole Body Vibration in People With Chronic Stroke

June 9, 2019 updated by: Marco Yiu-Chung Pang, The Hong Kong Polytechnic University

The Effects of Whole Body Vibration Training With Different Frequencies on Bone Health and Neuromotor Performance in Individuals With Chronic Stroke: A Randomized Controlled Trial.

Whole body vibration (WBV) has been found to be useful in promoting bone health and muscle performance in older adults. To date, no study has examined the effects of different WBV frequencies on the properties of the muscle-bone unit in stroke patients. The overall aim of the proposed study is to compare the efficacy of different vibration frequencies on properties of the muscle function and bone turnover among people with chronic stroke.

It is hypothesized that the higher-vibration frequency protocol will lead to significantly better outcomes related to the bone turnover and muscle function.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Whole body vibration (WBV) has been found to be useful in promoting bone health and muscle performance in older adults. To date, no study has examined the effects of different WBV frequencies on the properties of the muscle-bone unit in stroke patients. The overall aim of the proposed study is to compare the efficacy of different vibration frequencies on properties of the muscle function and bone turnover among people with chronic stroke.

It is hypothesized that the higher-vibration frequency protocol will lead to significantly better outcomes related to the bone turnover and muscle function in people with chronic stroke.

Study Type

Interventional

Enrollment (Actual)

80

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Hong Kong
      • Hongkong, Hong Kong
        • The Hong Kong Polytechnic University

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  1. a diagnosis of stroke
  2. stroke onset >6 months
  3. >18 years of age
  4. able to walk for short distance independently with or without walking aid
  5. able to understand simple verbal commands

Exclusion Criteria:

  1. neurological conditions other than stroke
  2. significant musculoskeletal conditions (e.g. amputations)
  3. metal implants in the lower extremity
  4. previous fracture of the lower extremity
  5. are currently taking bone resorption inhibitors or were taking the same before stroke.
  6. significant peripheral vascular disease
  7. vestibular disorders
  8. pregnancy
  9. Other serious illnesses that preclude the person from participating in the study

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: High frequency whole body vibration
This group will receive a single 8-minute session of WBV therapy. The frequency of the vibration signals will be set at 30Hz.
Procedure: High frequency whole body vibration
1 single session ( 8 minutes) of whole body vibration therapy at 30 Hz
Other Names:
  • Whole body vibration therapy (30Hz)
Active Comparator: low frequency whole body vibration
This group will receive a single 12-minute session of WBV. The frequency of the vibration signals will be set at 20 Hz.
Procedure: Low frequency whole body vibration
1 single session ( 12 minutes) of whole body vibration therapy at 20 Hz
Other Names:
  • Whole body vibration therapy (20Hz)

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
bone resorption marker
Time Frame: pre-test (week 0)
Serum level of aminoterminal crosslinked telopeptide
pre-test (week 0)
bone resorption marker
Time Frame: post-test (week8)
Serum level of aminoterminal crosslinked telopeptide
post-test (week8)

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Six Minute Walk Test
Time Frame: pre-test (week 0)
endurance test
pre-test (week 0)
Six Minute Walk Test
Time Frame: post-test (week8)
endurance Test
post-test (week8)
Gait velocity
Time Frame: pre-test (week 0)
10-meter walking test
pre-test (week 0)
Gait velocity
Time Frame: post-test (week8)
10-meter walking test
post-test (week8)
Spasticity
Time Frame: pre-test (week 0)
H-reflex on tibial nerve and modified ashworth scale
pre-test (week 0)
Spasticity
Time Frame: post-test (week8)
H-reflex on tibial nerve and modified ashworth scale
post-test (week8)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

The Hong Kong Polytechnic University

Investigators

  • Principal Investigator: Marco YC Pang, PhD, The Hong Kong Polytechnic University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

June 28, 2017

Primary Completion (Actual)

June 28, 2018

Study Completion (Actual)

August 28, 2018

Study Registration Dates

First Submitted

June 6, 2019

First Submitted That Met QC Criteria

June 9, 2019

First Posted (Actual)

June 11, 2019

Study Record Updates

Last Update Posted (Actual)

June 11, 2019

Last Update Submitted That Met QC Criteria

June 9, 2019

Last Verified

June 1, 2019

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • HSEARS20140226001-03

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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