the Effect of Different Modialites of Varicocelectomy on Semen Parameters in Patient With Normal Semen Analysis

September 11, 2017 updated by: Abdelrahman Mohamed Abdelkader, Assiut University

Comparison Between Impact of Inguinal and Subinguinal Approaches of Varicocelectomy on Semen Parameters in Patients With Normal Semen Analysis

to evalute the effect inguinal and subinguinal approach of varicoceclectomy on semen parameter for patients complaining of varicocele with normal semen parameter (pain is the main complaint)

Study Overview

Status

Unknown

Conditions

Intervention / Treatment

Detailed Description

the varicocele is defined as dilated and incompetent veins within the pampiniform plexus of spermatic cord. varicocele has been described as the most common surgically correctable cause of male subinfertility.this is a disease that devolops during puberty when both endocrine and exocrine function of the testicle dramatically increases, along with testicular blood flow. varicocele only rarely detected in boys less than 10 years. left sided varicocle found in 15% of healthy young men.incontrast, the incidence in sub fertile men approaches 40% bilateral varicocele is uncommon in healthy men (less than 10%) but palpated in 20% in sub fertile men. in-general varicocele don't spontaneously regress. an accurate physical examination remain the corner stone of varicocele diagnosis.

several anatomic features contribute to the predominance of left sided varicocele is the left intrnal spermatic vein longer than the right and it typically joins the left renal vein at a right angle.as result of this character higher venous pressures fair transmited to the left spermatic vein and result in reterograde reflux of blood.

varicocle are associated with testicular atrophhy and varicocle correction can reverse atrophy in adolececnt. there is strong evidence affect semen quality it can cause abnormalties in concentration, motility and morphology.main defect is the motility.

indication of varicocelectomy:

  1. Large varicoceles in adolescents
  2. Childhood varicocele with testicular atrophy
  3. Varicoceles with elevated FSH values, or low testosterone levels
  4. Varicoceles with scrotal pain
  5. Cosmetic indication
  6. Male infertility with pathological semen analysis and varicocele

Study Type

Observational

Enrollment (Anticipated)

32

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

  • Name: Mohamed A Osman, professor
  • Phone Number: 0882315760 01062226639
  • Email: osman@aun.edu.eg

Study Locations

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

19 years to 45 years (ADULT)

Accepts Healthy Volunteers

No

Genders Eligible for Study

Male

Sampling Method

Non-Probability Sample

Study Population

Male patients undergoing varicocelectomy while having normal semen parameters (doing surgery for other reasons eg. pain)

Description

Inclusion Criteria:

  • age more than 19 years old
  • primary varicocele

Exclusion Criteria:

  • secondary varicocele recurrent varicocele age less than 19 years

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
high inguinal approch
Patients undergoing high inguinal varicocelectomy with normal pre operative semen parameters, post operative semen analysis parameters will be recorded
Procedure: High inguinal Varicocelectomy
Semen parameters after high inguinal varicocelectomy will be collected
subinguinal approch
Patients undergoing subinguinal varicocelectomy with normal pre operative semen parameters, post operative semen analysis parameters will be recorded
Procedure: Subinguinal varicocelectomy
Semen parameters after subinguinal Varicocelectomy will be collected

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Semen analysis
Time Frame: 3months
Motility morphology concentration
3months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Assiut University

Investigators

  • Study Director: Ehab O Ahmed, unaffiliation
  • Study Chair: Mohamed I Taha, unaffiliation
  • Study Director: Ahmed k mohamed, unaffiliation

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (ANTICIPATED)

October 15, 2017

Primary Completion (ANTICIPATED)

October 15, 2018

Study Completion (ANTICIPATED)

October 15, 2018

Study Registration Dates

First Submitted

August 25, 2017

First Submitted That Met QC Criteria

September 11, 2017

First Posted (ACTUAL)

September 13, 2017

Study Record Updates

Last Update Posted (ACTUAL)

September 13, 2017

Last Update Submitted That Met QC Criteria

September 11, 2017

Last Verified

September 1, 2017

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • varicocelectomy

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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