The German Keratoplasty Registry of the German Ophthalmological Society (DOG)

April 22, 2026 updated by: Elias Flockerzi, Universität des Saarlandes

Trends in Corneal Transplantation From 2001 in Germany: Reports of the DOG-Section Cornea and Its Keratoplasty Registry

Aim of this study is to reflect on the changing trends in absolute numbers, surgical techniques and indications of corneal transplantations being performed in Germany.

The Section Cornea of the German Ophthalmological Society provides interim-assessments on a regular basis about the most up-to-date results of this long-term study.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

100000

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • Germany
    • Saarland
      • Homburg, Saarland, Germany, 66421
        • Recruiting
        • Department of Ophthalmology
        • Contact:
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

2 years to 96 years (Child, Adult, Older Adult)

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

All patients in Germany treated with the different types of corneal transplantation since 2001.

Description

Inclusion Criteria:

All patients in Germany treated with the different types of corneal transplantation since 2001.

Exclusion Criteria:

Patients without corneal transplantation.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Cohort
  • Time Perspectives: Other

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Patients with corneal transplantation
Aim is to include all patients in Germany treated with the different types of corneal transplantation.
Procedure: Corneal transplantation
PKP: Penetrating Keratoplasty DALK: Deep Anterior Lamellar Keratoplasty DMEK: Descemet Membrane Endothelial Keratoplasty DSAEK: Descemet's Stripping Automated Endothelial Keratoplasty
Other Names:
  • PKP, DALK, DMEK, DSAEK

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
An overview about absolute numbers of corneal transplantation in Germany.
Time Frame: 01/01/2001 to 31/12/2031
A questionnaire about absolute numbers of corneal transplantation per year was sent to the 111 ophthalmological departments in Germany performing corneal transplantation. Data has been and is collected annually since 2001.
01/01/2001 to 31/12/2031
An overview about trends in the various types of corneal transplantation in Germany.
Time Frame: 01/01/2001 to 31/12/2031
The questionnaire also records the types of corneal transplantation (i.e. penetrating keratoplasty, deep anterior lamellar keratoplasty, Descemet membrane endothelial keratoplasty (DMEK) and Descemet's stripping automated endothelial keratoplasty DSAEK) allowing a discussion of trends in corneal transplantation. Data has been and is collected annually since 2001.
01/01/2001 to 31/12/2031
An overview about indications for corneal transplantation in Germany.
Time Frame: 01/01/2001 to 31/12/2031
The questionnaire also records the indications for corneal transplantation (e.g. Fuchs' endothelial corneal dystrophy, pseudophakic corneal decompensation, repeated keratoplasty after graft failure, keratoconus and corneal scarring). Data has been and is collected annually since 2001.
01/01/2001 to 31/12/2031

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Universität des Saarlandes

Collaborators

Charite University, Berlin, Germany
University of Erlangen-Nürnberg
University Eye Hospital, Freiburg
Heinrich-Heine University, Duesseldorf
University of Cologne

Investigators

  • Study Director: Berthold Seitz, Prof.Dr.med., Universität des Saarlandes

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2001

Primary Completion (Estimated)

January 1, 2036

Study Completion (Estimated)

January 1, 2036

Study Registration Dates

First Submitted

December 11, 2017

First Submitted That Met QC Criteria

December 18, 2017

First Posted (Actual)

December 22, 2017

Study Record Updates

Last Update Posted (Actual)

April 27, 2026

Last Update Submitted That Met QC Criteria

April 22, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • GeKeR

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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