Information and Accompaniment of Siblings Following the Announcement of a Cancer in Pediatric Hematology.

The primary objective is to evaluate the experience with the information received on the disease by the healthy brothers and sisters of childrens with malignant haemopathy at the Centre Hospitalier Régional et Universitaire of Lille

Study Overview

• Status: Terminated
• Conditions: Malignant Haemopathy
• Intervention / Treatment: Other: semi-directive interview

• Study Type: Interventional
• Enrollment (Actual): 7
• Phase: Not Applicable

Contacts and Locations

Study Locations

• France
  • Lille, France
    • Hôpital Jeanne de Flandres, CHU

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 6 years to 12 years (Child)
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• Children from 6 to 12 years old
• Brother or sister of a child:

O has malignant haemopathy O follow-up in the pediatric hematology department in Lille, O diagnosed from 6 weeks to 1 year before maintenance of the healthy subject included

• whose parents are able to understand and sign voluntarily informed consent
• Affiliated to a social security scheme
• Ability to understand and answer questions alone during the semi-structured interview

Exclusion Criteria:

• Child under 6 years or over 12 years
• Subject with a pathology that may interfere with the course of the study, according to the investigator's assessment
• Absence of the informed consent of one of the parents and / or the legal representative
• Refusal of participation of the subject

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Other
• Allocation: N/A
• Interventional Model: Single Group Assignment
• Masking: None (Open Label)

Number of Arms

1

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Other: siblings; Brother or sister of a child has malignant haemopathy and follow-up in the pediatric hematology department	Other: semi-directive interview; semi-structured interview conducted by a clinical psychologist

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Level of satisfaction and characteristics of information received about the disease by healthy siblings of children with hematological malignancies	Measure Qualitative Interviews by Grounded theory. The experience with the information received on the disease by the healthy brothers and sisters of childrens with malignant haemopathy. Assessment of the level of satisfaction with the information received. The information will be characterized according to three dimensions: the framework (by whom, with whom, where, when, how) and the content of the information	1 year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Explore the representations of the disease in healthy siblings	The representation of the disease is the set of personal beliefs of an individual about the disease. It allows him to make sense of the disease. These data will be analyzed during the semi-structured interview	1 year
Evaluate their information and support needs following the announcement of the disease	information and support needs gathered during the semi-structured interview	1 year
Identify the possible psychic and social consequences of the disease in these healthy subjects	to identify during the semi-directive interview the elements informing about the social behavior and the psychic state of the subject included, expressed spontaneously by the subject, directly (in the speech, for example "I am sad") or indirectly (by attitude, for example: crying)	1 year

Collaborators and Investigators

• Sponsor: University Hospital, Lille
• Investigators: Principal Investigator: Eva De Berranger, MD, University Hospital, Lille

Study record dates

Study Major Dates

• Study Start (Actual): October 22, 2018
• Primary Completion (Actual): April 1, 2019
• Study Completion (Actual): April 1, 2019

Study Registration Dates

• First Submitted: March 8, 2017
• First Submitted That Met QC Criteria: May 17, 2018
• First Posted (Actual): May 30, 2018

Study Record Updates

• Last Update Posted (Actual): December 11, 2025
• Last Update Submitted That Met QC Criteria: December 4, 2025
• Last Verified: December 1, 2025

More Information

Terms related to this study

• Keywords: information; Siblings; malignant haemopathy
• Other Study ID Numbers: 2016_83; 2016-A02091-50 (Other Identifier: ID-RCB Number, ANSM)

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No