Psychological Strengths and Burden Among Osteoarthritis Patient

Positive and Negative Affects Among Osteoarthritis Patient

Osteoarthritis (OA) is a common and debilitating disease, For the majority of patients, pain in OA is episodic in nature.

The experience of pain is generated or modified by nociception, neuropathic symptoms, psychological and personality factors, genetic influences, past painful experiences, comorbid conditions, and expectations related to future pain Previous studies have shown psychological well-being has been significantly associated with disability in patients with OA, and anxiety has been found to be associated with knee pain in women.

Previous studies also found that there are large interindividual differences among persons with knee osteoarthritis (OA) with respect to psychological function.

Psychological strengths and weaknesses are evaluated among new patient with osteoarthritis presented to joint replacement clinic, to facilitate our understanding of those patients need, and correlating with their radiological and clinical findings. Psychological strengths and weaknesses, positive and negative affects are evaluated in form of questionaires.

Reference:

Adaptation to disability: Applying selective optimization with compensation to the behaviors of older adults with osteoarthritis.

MAM Gignac, C Cott, EM Badley - Psychology and aging, 2002

Analgesic effects of multisensory illusions in osteoarthritis C Preston, R Newport - Rheumatology, 2011

Psychological factors and their relation to osteoarthritis pain BL Wise, J Niu, Y Zhang, N Wang, JM Jordan… - Osteoarthritis Cartilage. , 2010 - Elsevier

Study Overview

• Status: Completed
• Conditions: Osteoarthritis, Knee; Psychological

Detailed Description

Introduction:

Osteoarthritis (OA) is a prevalent painful condition that may cause disability among older adults (Cruz-Almeida et al., 2013). Psychological traits and emotional states of patients were found to be correlated with symptoms of OA and daily functioning of patients (Cruz-Almeida et al., 2013; Dezutter et al., 2015).

The experience of pain is generated or modified by nociception, neuropathic symptoms, psychological and personality factors, genetic influences, past painful experiences, comorbid conditions, and expectations related to future pain. Previous studies have shown psychological well-being has been significantly associated with disability in patients with OA, and anxiety has been found to be associated with knee pain in women.

Previous studies also found that there are large interindividual differences among persons with knee osteoarthritis (OA) with respect to psychological function.

Aim of project:

This research is trying to find out what psychological strengths or factors could attenuate the chronic pain of knee OA patients. The purpose of the study is to find psychological evidences that may be used in the future to help chronic pain patients for improving their daily functioning and well-being.

• Study Type: Observational
• Enrollment (Actual): 150

Contacts and Locations

Study Locations

• Hong Kong
  • Tai Po, Hong Kong
    • Alice Ho Miu Ling Nethersole Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 65 years and older (Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

150 patients, based on previous studies (Psychological Profiles and Pain Characteristics of Older Adults With Knee Osteoarthritis; Psychological factors and their relation to osteoarthritis pain) and the number of patients and study time available in our clinic

Those are all the new patient present to AHNH clinic referred for osteoarthritis for considering joint replacement

Description

Inclusion Criteria:

• all new patient present to AHNH clinic referred for osteoarthritis for considering joint replacement
• Present with knee pain (unilateral or bilateral) contributed by osteoarthritis

Exclusion Criteria:

• mentally unsound
• dialectic speaker that difficult to communicate

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Osteoarthritis; All new patient present to clinic referred for osteoarthritis for considering joint replacement Present with knee pain (unilateral or bilateral) contributed by osteoarthritis

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Positive and Negative Affect Scale (PANAS)	This scale consists of a number of questions that describe different feelings and emotions.	1 day
The Centre for Epidemiologic Studies (CES-D Scale)	A list of the ways the subject might have felt or behaved.	1 day
The Chronic Pain Acceptance Questionnaire (CPAQ)	Statements on feelings on pain as it applies to the subject.	1 day
Chronic Pain Coping Inventory (CPCI-42)		1 day
VIA-72	Questions reflect statements that the subject would find desirable.	1 day
Kellgren & Lawrence (K & L) grading system	To classify the severity of knee osteoarthritis (OA)	1 day
Oxford knee scores	Consists of 12 questions that cover function and pain of the knee.	1 day

Collaborators and Investigators

• Sponsor: Chinese University of Hong Kong

Study record dates

Study Major Dates

• Study Start (Actual): June 1, 2018
• Primary Completion (Actual): December 1, 2019
• Study Completion (Actual): December 1, 2019

Study Registration Dates

• First Submitted: March 28, 2019
• First Submitted That Met QC Criteria: April 1, 2019
• First Posted (Actual): April 2, 2019

Study Record Updates

• Last Update Posted (Actual): January 23, 2020
• Last Update Submitted That Met QC Criteria: January 21, 2020
• Last Verified: January 1, 2020

More Information

Terms related to this study

• Keywords: osteoarthritis; psychology
• Additional Relevant MeSH Terms: Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Arthritis; Osteoarthritis; Osteoarthritis, Knee
• Other Study ID Numbers: 2018.113

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No