Transport Distraction Osteogenesis for Ramus-Condyle Unit

July 22, 2020 updated by: Hams Hamed Abdelrahman

Transport Distraction Osteogenesis for Reconstruction of Ramus-Condyle Unit Following Release of Temporomandibular Joint Ankylosis

this study was done to evaluate the use of transport distraction osteogenesis in restoring the deficient condyle/ramus unit of patients with unilateral or bilateral TMJ ankylosis to correct the resultant deformity

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

10 patients with post ankylosis deficient ramus /condyle unit who underwent release procedure in the Maxillofacial and Plastic Surgery Department, Faculty of Dentistry, Alexandria University, Egypt.

all patients were assessed clinically and by imaging using OPG, lateral and PA cephalometry, and cone beam CT to assess the deficient ramus/condyle unit (RCU) then patients were operated using transport distraction osteogenesis to lengthen the RCU. Then follow up of all patients both clinically and radiographically was adopted.

Study Type

Interventional

Enrollment (Actual)

10

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
    • Azarita
      • Alexandria, Azarita, Egypt, 00203
        • Faculty of Dentistry

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

1 year to 50 years (Child, Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Post ankylosis deformity: Bilateral or unilateral deficient ramus-condyle unit (RCU) after TMJ release

Exclusion Criteria:

  • Mentally affected patients.
  • Medically compromised patients.
  • Post menopausal osteoporosis.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Transport distraction osteogenesis

Locally made and designed submerged monodirectional in the vertical (Y) axis distractor was used.

A transport disc is created at the remaining stump of the RCU with an L shaped osteotomy.

The prepared disc is to be wide enough to fit the upper portion of the distrcator.

The submerged distractor will be placed in a position to guide the transport disc moving up and backwards toward the glenoid fossa.

The length of the distractor is determined according to the amount of distraction planned to reach the glenoid fossa.
Device: Distraction Osteogenesis for Reconstruction of Ramus-Condyle
transport distraction osteogenesis in restoring the deficient condyle/ramus unit of patients with TMJ ankylosis to correct the resultant deformity either unilaterally or bilaterally.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Jaw movements (changes in jaw movements through 18 months follow up)
Time Frame: at 3rd, 6th and 18th months
Mouth opening in mm, Jaw movement in lateral excursion and opening.
at 3rd, 6th and 18th months
Ramus height (changes of ramus heights through 18 months follow up)
Time Frame: at 3rd and 6th months
Determination of the height of the ramus by PA cephalometric, Lateral cephalometric x-rays and tracings
at 3rd and 6th months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Occlusal discrepancy or anterior open bite
Time Frame: 18th months
Occlusal discrepancy or anterior open bite
18th months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Hams Hamed Abdelrahman

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

January 1, 2018

Primary Completion (Actual)

April 27, 2018

Study Completion (Actual)

July 15, 2019

Study Registration Dates

First Submitted

May 6, 2020

First Submitted That Met QC Criteria

May 7, 2020

First Posted (Actual)

May 12, 2020

Study Record Updates

Last Update Posted (Actual)

July 23, 2020

Last Update Submitted That Met QC Criteria

July 22, 2020

Last Verified

July 1, 2020

More Information

Terms related to this study

Other Study ID Numbers

  • Distraction Osteogenesis

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Bilateral or Unilateral Deficient Ramus-condyle Unit

Clinical Trials on Distraction Osteogenesis for Reconstruction of Ramus-Condyle

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Belgium

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe