Comparison of Erector Spinae Plane Block and Intravenous Analgesic in Nefrectomy
March 14, 2021 updated by: Zehra Ipek ARSLAN, Kocaeli University
Erector Spinae Plane Block for Nefrectomy
The efficacy of erector spinae plane block versus intravenous analgesics compared relate to the morphine consumptions
Study Overview
Status
Completed
Conditions
Detailed Description
Patients undergoing elective nefrectomy were enrolled.
Patients divided into two groups with a sealed envelope technique to ESP+ pca morphine group or iv analgesic + pca morphine group.
All patients will premedicated.
then esp will applied to one group before surgery at the preoperative care unit by the same anesthesiologist.
The other group will receive intravenous tramadol 1 mg/kg + NSAID 1 ampule + parol 10 mg/ kg + ondansetron 4 mg bolus.
İntravenous morphine pca with a concentration of 0.5 mg/cc were applied.
And administered 1 mg boluses every 15 minutes lock time and 4 hour limit as 4 mg arranged.
An anesthesia nurse who is responsible of all pcas' in the hospital was recorded the variables of these patients in the service
Study Type
Interventional
Enrollment (Actual)
46
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Kocaeli, Turkey
- Kocaeli University Medical Faculty
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 65 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:18-65 years age
- ASA I-II
- undergoing elective nephrectomy
Exclusion Criteria:- ASA>3
- heart disease
- pregnancy
- lung disease
- scoliosis
- bleeding disorder
- infection at the manipulation side
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Diagnostic
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Double
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Active Comparator: postoperative opiod (morphine) consumption
patient-controlled analgesia (15 minutes.
lock time, 2 ml bolus= total 1 mg morphine intravenously, limited to maximum 4 bolus / per hour )
|
erector spinae plane block applied in this group before open nephrectomy
intarvenous analgesic administered in this group for analgesia end of the open nephrectomy
|
|
Active Comparator: peroperative continuous opioid (remifentanil) consumption
continuous remifentanil infusion was given during the whole procedure
|
erector spinae plane block applied in this group before open nephrectomy
intarvenous analgesic administered in this group for analgesia end of the open nephrectomy
|
|
Active Comparator: postoperative numerated rating scale
at the 1, 3, 6, 12 and 24 th hour postoperatively - numerated rating scale score was evaluated and recoded as 0= no pain (better), 10: unbearable pain (worse)
|
erector spinae plane block applied in this group before open nephrectomy
intarvenous analgesic administered in this group for analgesia end of the open nephrectomy
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Postoperative intravenous morphine patient controlled analgesia consumption
Time Frame: during postoperatively
|
morphine consumptions were recorded till 24 th hour postoperatively
|
during postoperatively
|
|
Peroperative remifentanyl consumption
Time Frame: Peroperatively
|
Amount of Remifentanyl consumption recorded
|
Peroperatively
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Visual analog rating scores
Time Frame: during postoperative surgery
|
pain scores were recorded during surgery
|
during postoperative surgery
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
December 30, 2020
Primary Completion (Actual)
March 10, 2021
Study Completion (Actual)
March 10, 2021
Study Registration Dates
First Submitted
December 7, 2020
First Submitted That Met QC Criteria
December 23, 2020
First Posted (Actual)
December 29, 2020
Study Record Updates
Last Update Posted (Actual)
March 16, 2021
Last Update Submitted That Met QC Criteria
March 14, 2021
Last Verified
March 1, 2021
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- KIA 2020/96
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
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