- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04890470
Effects of Oxytocin and Vasopressin on Moral Decision Making
September 19, 2023 updated by: Keith Kendrick, University of Electronic Science and Technology of China
To determine whether the neuropeptide oxytocin (OXT) and vassopressin (AVP) influence moral decision making
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
In a double-blind, between- subject placebo (PLC) controlled design, subjects will first complete a series of questionnaires in terms of mood, clinical symptoms, and traits.
After that their moral judgment and emotion towards both verbal descriptions of moral dilemma scenarios and pictures of specific interpersonal ones will be assessed and the effect of intranasal OXT and AVP between both male and female healthy subjects will be investigated.
Study Type
Interventional
Enrollment (Actual)
180
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Keith M. Kendrick, Dr.
- Phone Number: 86-28-61830811
- Email: k.kendrick.uestc@gmail.com
Study Locations
-
-
Sichuan
-
Sichuan, Sichuan, China, 611731
- Xiaoxiao Zheng
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 30 years (Adult)
Accepts Healthy Volunteers
Yes
Description
Inclusion Criteria:
- healthy subjects without past or current psychiatric or neurological disorders
Exclusion Criteria:
- pregnancy
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Double
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: oxytocin group
subjects with oxytocin treatment
|
intranasal administration of oxytocin (24 IU)
|
Experimental: vasopressin group
subjects with vasopressin treatment
|
intranasal administration of vasopressin (20 IU)
|
Placebo Comparator: placebo group
subjects with placebo treatment
|
intranasal administration of placebo
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Effect of OXT and AVP on behavioral index of moral decision task
Time Frame: 45 mins - 105 mins
|
intensity of feelings
|
45 mins - 105 mins
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Principal Investigator: Keith M. Kendrick, University of Electronic Science and Technology of China
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
March 2, 2021
Primary Completion (Actual)
December 12, 2022
Study Completion (Actual)
December 12, 2022
Study Registration Dates
First Submitted
May 12, 2021
First Submitted That Met QC Criteria
May 16, 2021
First Posted (Actual)
May 18, 2021
Study Record Updates
Last Update Posted (Actual)
September 21, 2023
Last Update Submitted That Met QC Criteria
September 19, 2023
Last Verified
September 1, 2023
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- UESTC-neuSCAN-78
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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