Subjective and Objective Changes in Muscle-stiffness

The Relationship Between Subjective and Objective Changes in Muscle-stiffness

The purpose of this study is to investigate muscle stiffness in relation to delayed on-set muscle soreness following exercise and to investigate how well the change in muscle stiffness correlates with the subjective experienced degree of stiffness.

Study Overview

• Status: Recruiting
• Conditions: Healthy; Muscle Soreness
• Intervention / Treatment: Other: Exercise

• Study Type: Interventional
• Enrollment (Anticipated): 30
• Phase: Not Applicable

Contacts and Locations

• Study Contact: Name: Steffan WM Christensen, PhD; Phone Number: +45 99408889; Email: stc@hst.aau.dk

Study Locations

• Denmark
  • Aalborg, Denmark, 9220
    • Recruiting
    • Dept. Of Health Science and Technology, Aalborg University
    • Contact: Steffan W Christensen, PhD

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 60 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

Description

Inclusion Criteria:

• Healthy participants aged 18-80
• Able to speak, read and understand Danish and/or English

Exclusion Criteria:

• Have performed resistance training on a regular basis during the past month
• Experience of delayed onset muscle soreness (DOMS) during the last two weeks leading up to the first test session
• Current use of analgesics
• Any current neurological, musculoskeletal or mental illnesses that could interfere with the results.
• Pregnancy
• Lack of ability to cooperate

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Diagnostic
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
No Intervention: Control; Participants will not perform any exercise
Experimental: Exercise; Participants will perform an exercise recommended for preventing neck and shoulder pain	Other: Exercise; Upper limb exercises using an elastic band.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Muscle stiffness (change) - Shear wave	Muscle stiffness measured by ultrasound using shear wave elastography	Day1,Day 2 and Day7

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Muscle stiffness (change) - Self-reported	Self-reported muscle stiffness: Measured on a NRS scale (0-10), where 0 = not stiff at all, 10 is maximal stiffness	Day1,Day 2 and Day7
Muscle stiffness (change) - Myotonometry	Muscle stiffness measured by Myotonometry	Day1,Day 2 and Day7
Muscle stiffness (change)- Palpation	Muscle palpation: Reported using a 5-point Likert: 1 = very low muscle stiffness and 5 = very high muscle stiffness	Day1,Day 2 and Day7

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Muscle thickness	Muscle thickness measured by ultrasound	Day1,Day 2 and Day7
Muscle soreness	Self-reported muscle soreness: Measured on a NRS scale (0-10), where 0 = not sore at all, 10 is maximal soreness	Day1,Day 2 and Day7
Neck disability	The NDI is questionnaire investigating neck pain and disability: Scores range from 0 to 50. Higher score represent worse disability	Day1,Day 2 and Day7
Shoulder disability	SPADI is a 13-item questionnaire investigating shoulder pain and disability: Scores range from 0 to 130. Higher score represent worse disability	Day1,Day 2 and Day7

Collaborators and Investigators

• Sponsor: Aalborg University
• Investigators: Principal Investigator: Steffan WM Christensen, PhD, Aalborg University

Study record dates

Study Major Dates

• Study Start (Actual): February 21, 2022
• Primary Completion (Anticipated): May 31, 2023
• Study Completion (Anticipated): July 31, 2023

Study Registration Dates

• First Submitted: February 16, 2022
• First Submitted That Met QC Criteria: March 4, 2022
• First Posted (Actual): March 15, 2022

Study Record Updates

• Last Update Posted (Actual): March 15, 2022
• Last Update Submitted That Met QC Criteria: March 4, 2022
• Last Verified: March 1, 2022

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Nervous System Diseases; Pain; Neurologic Manifestations; Musculoskeletal Diseases; Muscular Diseases; Neuromuscular Diseases; Musculoskeletal Pain; Myalgia
• Other Study ID Numbers: AAU031-1004903

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: No

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No