Lifetime Incidence and Socio-economic Implications of Mental Illness

Lifetime Incidence and Socio-economic Implications of Mental Illness - a Nationwide Population-based Cohort Study

The purpose of the present study is to estimate the lifetime incidence of any mental disorder in a nationwide population-based register linkage study for the Danish population and to estimate the influence on socio-economic functioning.

Study Overview

• Status: Completed
• Conditions: Mental Illness
• Intervention / Treatment: Other: Not relevant

Detailed Description

The purpose of the present study is to estimate the lifetime incidence of any mental disorder in a nationwide population-based register linkage study for the Danish population in total and according to gender and to estimate the influence on socio-economic functioning. The investigaters hypothesised that the lifetime incidence of any mental disorder is substantially higher than hitherto believed.

• Study Type: Observational
• Enrollment (Actual): 1500000

Contacts and Locations

Study Locations

• Denmark
  • Copenhagen, Denmark, 2100
    • Psychiatric Center Copenhagen

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 1 year to 110 years (Child, Adult, Older Adult)
• Accepts Healthy Volunteers: N/A
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

The study was based on a randomly selected 1,500,000 sample of all persons who were registered in Statistics Denmark on the 1st of January 1995.

Description

Inclusion Criteria:

• The study was based on a randomly selected 1,500,000 sample of all persons who were registered in Statistics Denmark on the 1st of January 1995.

Exclusion Criteria:

• None

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Patients; Patients with mental illness according to Danish health registers	Other: Not relevant; This is a non-intervention cohort study
Control individuals from the general population; Control individuals from the general population matched according to the data of diagnosis/ psychotropic medication, year of birth, sex and calendar year.	Other: Not relevant; This is a non-intervention cohort study

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Any psychiatric disorder or any psychotropic medication according to data in Danish nationwide registers	Cumulative incidens of any psychiatric disorder or psychotropic medication for any mental illness except sleep disorders, dementia and nicotine dependence in total and according to sex	January 1, 1995 to December 31, 2020

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Diagnosis of any psychiatric disorder according to data in Danish nationwide registers	Cumulative incidence of a diagnosis of any psychiatric disorder in total and according to sex	January 1, 1995 to December 31, 2020

Other Outcome Measures

Outcome Measure	Measure Description	Time Frame
Socio-economic functioning in relation to individuals recorded with the primary outcome according to data in Danish nationwide registers	Socio-economic functioning	January 1, 1995 to December 31, 2020

Collaborators and Investigators

• Sponsor: Mental Health Services in the Capital Region, Denmark
• Collaborators: University of Copenhagen

Study record dates

Study Major Dates

• Study Start (Actual): June 7, 2022
• Primary Completion (Actual): June 7, 2022
• Study Completion (Actual): June 7, 2022

Study Registration Dates

• First Submitted: June 7, 2022
• First Submitted That Met QC Criteria: June 7, 2022
• First Posted (Actual): June 13, 2022

Study Record Updates

• Last Update Posted (Actual): June 14, 2022
• Last Update Submitted That Met QC Criteria: June 10, 2022
• Last Verified: June 1, 2022

More Information

Terms related to this study

• Keywords: Mental Illness
• Additional Relevant MeSH Terms: Mental Disorders
• Other Study ID Numbers: Lifetime incidence

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO
• IPD Plan Description: Data for this study is property of Statistic Denmark and the Danish Health Data Authority. The data are available from the authorities, but restrictions apply.

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No