Effect of Glossopharyngeal Versus Diaphragmatic Breathing Exercise on Pulmonary Function After Decortication Surgery

This study will be conducted to compare between the effect of glossopharyngeal and diaphragmatic breathing exercises on pulmonary functions after decortication surgery

Study Overview

• Status: Completed
• Conditions: Pulmonary Disease
• Intervention / Treatment: Other: traditional chest techniques; Other: Glossopharyngeal breathing exercise; Other: Diaphragmatic breathing exercise

Detailed Description

Lung decortication is a well-known procedure for the treatment of empyema. Persistent lung collapse and non-expansion of the lung parenchyma are frequently noticed in the postoperative period after decortications, chest physiotherapy plays a crucial role in the re-expansion of underlying parenchyma.

There is an increased flow of patients after decortication surgery to hospitals who suffer from decreased lung volumes so the hospitalization period for them increases which puts an economical burden on health insurance services with a decreased level of quality of life that is the most concern to improve patient status and relieve this burden. So this study aims to improve patient's lung volumes and arterial blood gas parameters which improves patient status through two various forms of breathing exercises.

• Study Type: Interventional
• Enrollment (Actual): 60
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Egypt
  • Cairo, Egypt
    • Mai Gamal El-Din Mostafa

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

Description

Inclusion Criteria:

• The participant's body mass index (BMI) will be ranged from 25- 29.9 kg/m2
• The patient will receive treatment after 24 hours after decortication
• The study will be in the intensive care unit (ICU).
• The patients have unilateral lung decortication
• Their vital capacity is 70% or less.

Exclusion Criteria:

• Cancerous patient.
• Inability to comprehend and follow instructions as in dementia
• paralytic involvement of thorax muscle
• Abdominal diseases that affect diaphragmatic function
• Diaphragmatic paralysis

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

3

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Traditional chest techniques; the patients will receive traditional chest techniques only	Other: traditional chest techniques; patients will receive traditional chest techniques in the form of percussion and vibration, 2 times per day, 3 sets 5 repetitions per each set for 20 minutes, 3 times per week for 2 weeks
Experimental: Traditional chest techniques +Glossopharyngeal breathing exercise; the patients will receive traditional chest techniques and glossopharyngeal breathing exercise	Other: traditional chest techniques; patients will receive traditional chest techniques in the form of percussion and vibration, 2 times per day, 3 sets 5 repetitions per each set for 20 minutes, 3 times per week for 2 weeks; Other: Glossopharyngeal breathing exercise; patients will receive Glossopharyngeal breathing exercise, 2 times per day, 3 sets 5 repetitions per each set for 20 minutes, 3 times per week for 2 weeks.
Experimental: Traditional chest techniques +diaphragmatic breathing exercise; the patients will receive traditional chest techniques and diaphragmatic breathing exercise	Other: traditional chest techniques; patients will receive traditional chest techniques in the form of percussion and vibration, 2 times per day, 3 sets 5 repetitions per each set for 20 minutes, 3 times per week for 2 weeks; Other: Diaphragmatic breathing exercise; patients will receive diaphragmatic breathing exercise, 2 times per day, 3 sets 5 repetitions per each set for 20 minutes, 3 times per week for 2 weeks.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Tidal volume	The spirometer device (Meditech, made in China) will be used to measure tidal volume for all participants in all groups before and after the treatment program. It is the amount of air that moves in or out of the lungs with each respiratory cycle. It measures about 400 ml in a healthy female.	within 2 weeks
Inspiratory reserve volume (IRV)	The spirometer device (Meditech, made in China) will be used to measure inspiratory reserve volume (IRV) for all participants in all groups before and after the treatment program. - IRV: It is the amount of air that can be forcibly inhaled after normal tidal volume. The normal adult value is 1900-3300 ml.	within 2 weeks
Expiratory reserve volume (ERV)	The spirometer device (Meditech, made in China) will be used to measure expiratory reserve volume (ERV) for all participants in all groups before and after the treatment program. ERV: It is the amount of extra air above normal breath-exhaled during forceful breath out, its average is about 800ml in females.	within 2 weeks
Measurement of the potential of hydrogen (PH)	Blood gas analyzer will be used to measure the potential of hydrogen (PH) for all participants in all groups before and after the treatment program. The blood sample was taken from the radial or brachial or femoral artery or from arterial catheter and put in the device. The normative value of pH is7.35-7.45	within 2 weeks
Measurement of the partial arterial pressure of carbon dioxide(PaCO2)	Blood gas analyzer will be used to measure the partial arterial pressure of carbon dioxide(PaCO2) for all participants in all groups before and after the treatment program. The blood sample was taken from the radial or brachial or femoral artery or from arterial catheter and put in the device. the normative value of PaCO2 is 4.7-6 KPa.	within 2 weeks
Measurement of the partial arterial pressure of oxygen (PaO2)	Blood gas analyzer will be used to measure the partial arterial pressure of oxygen (PaO2)for all participants in all groups before and after the treatment program. The blood sample was taken from the radial or brachial or femoral artery or from arterial catheter and put in the device. the normative value of Pao2 is 1.7-13.3 KPa.	within 2 weeks
Measurement of the Bicarbonate (HCO3)	Blood gas analyzer will be used to measure the Bicarbonate (HCO3) for all participants in all groups before and after the treatment program. The blood sample was taken from the radial or brachial or femoral artery or from arterial catheter and put in the device. The normative value of HCO3 is 22-26 mmol/L.	within 2 weeks
Measurement of oxygen saturation (SO2)	Blood gas analyzer will be used to measure oxygen saturation (SO2) for all participants in all groups before and after the treatment program. The blood sample was taken from the radial or brachial or femoral artery or from arterial catheter and put in the device. The normative value of SO2 is 95-100%..	within 2 weeks

Collaborators and Investigators

• Sponsor: Cairo University
• Investigators: Study Chair: Nesreen El-Nahas, professor, Cairo University

Study record dates

Study Major Dates

• Study Start (Actual): July 30, 2024
• Primary Completion (Actual): March 15, 2025
• Study Completion (Actual): March 31, 2025

Study Registration Dates

• First Submitted: July 17, 2024
• First Submitted That Met QC Criteria: July 22, 2024
• First Posted (Actual): July 24, 2024

Study Record Updates

• Last Update Posted (Actual): April 17, 2025
• Last Update Submitted That Met QC Criteria: April 14, 2025
• Last Verified: July 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Respiratory Tract Diseases; Lung Diseases
• Other Study ID Numbers: P.T.REC/012/003896

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES
• IPD Sharing Supporting Information Type: STUDY_PROTOCOL

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No