- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT06798987
Based on the Data from the Zhejiang Emergency Center, Explore the Independent and Interactive Effects of the Association Between Meteorological Factors and Air Pollution and the Number of Emergency Personnel, Identify the Relevant Vulnerable Population Characteristics, Sensitive Disease Types
January 23, 2025 updated by: Li hengjie
Characterization of the Spatial Distribution and Drivers of the Association of Meteorological Factors and Air Pollution with the Number of First Aiders
Based on the health data from Zhejiang Emergency Command Center, combined with meteorological, air pollution, land use and socio-economic data of Zhejiang Province, distributional lag nonlinear models, grouped weighted quantile and regression and Bayesian spatial models were used to explore the independent and interactive effects of the association between meteorological factors and air pollution and the number of first-aiders, to identify the related characteristics of the vulnerable populations, the types of sensitive diseases and the high-risk areas, and to elucidate the driving factors of the association between meteorological factors and air pollution and the number of first-aiders.
It also clarifies the drivers of the association between meteorological factors and air pollution and the number of emergencies, so as to provide a reference for the government to take targeted measures to reduce the burden of related healthcare services.
Study Overview
Status
Enrolling by invitation
Conditions
Intervention / Treatment
Study Type
Observational
Enrollment (Estimated)
1500000
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Hangzhou, China
- Zhejiang Provincial People's Hospital
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
No
Sampling Method
Non-Probability Sample
Study Population
Number of emergency patients per hour at the emergency command center of Zhejiang Province
Description
Inclusion Criteria:
-Emergency data of Zhejiang Emergency Command Center in the past 5 years
Exclusion Criteria:
- Prehospital emergency information from non-Zhejiang province domains
- Emergency calls due to labor and delivery.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
|---|---|
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Number of first aiders per hour as assessed by R4.4.0
Time Frame: 6 months
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6 months
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Vulnerable population characteristics as assessed by R4.4.0
Time Frame: 6 Months
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6 Months
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Types of Sensitive Diseases as assessed by R4.4.0
Time Frame: 6 Month
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6 Month
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High-risk areas as assessed by R4.4.0
Time Frame: 6 months
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6 months
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
General Publications
- Cui Y, Ai S, Liu Y, Qian ZM, Wang C, Sun J, Sun X, Zhang S, Syberg KM, Howard S, Qin L, Lin H. Hourly associations between ambient temperature and emergency ambulance calls in one central Chinese city: Call for an immediate emergency plan. Sci Total Environ. 2020 Apr 1;711:135046. doi: 10.1016/j.scitotenv.2019.135046. Epub 2019 Nov 3.
- Bobb JF, Peng RD, Bell ML, Dominici F. Heat-related mortality and adaptation to heat in the United States. Environ Health Perspect. 2014 Aug;122(8):811-6. doi: 10.1289/ehp.1307392. Epub 2014 Apr 29.
- Phosri A, Ueda K, Seposo X, Honda A, Takano H. Effect modification by temperature on the association between O3 and emergency ambulance dispatches in Japan: A multi-city study. Sci Total Environ. 2023 Feb 25;861:160725. doi: 10.1016/j.scitotenv.2022.160725. Epub 2022 Dec 6.
- Wang X, Leng M, Liu Y, Qian ZM, Zhang J, Li Z, Sun L, Qin L, Wang C, Howard SW, Vaughn MG, Yan Y, Lin H. Different sized particles associated with all-cause and cause-specific emergency ambulance calls: A multicity time-series analysis in China. Sci Total Environ. 2021 Aug 20;783:147060. doi: 10.1016/j.scitotenv.2021.147060. Epub 2021 Apr 18.
- Michikawa T, Sasaki J, Yamazaki S, Takami A, Asakura K, Imamura H, Ueda K, Saito S, Hoshi J, Yoshino A, Sugata S, Nitta H, Nishiwaki Y. A Case-Crossover Analysis of the Association between Exposure to Total PM2.5 and Its Chemical Components and Emergency Ambulance Dispatches in Tokyo. Environ Sci Technol. 2022 Jun 7;56(11):7319-7327. doi: 10.1021/acs.est.1c08219. Epub 2022 May 24.
- Dawson LP, Andrew E, Nehme Z, Bloom J, Cox S, Anderson D, Stephenson M, Lefkovits J, Taylor AJ, Kaye D, Guo Y, Smith K, Stub D. Temperature-related chest pain presentations and future projections with climate change. Sci Total Environ. 2022 Nov 20;848:157716. doi: 10.1016/j.scitotenv.2022.157716. Epub 2022 Jul 29.
- Sangkharat K, Mahmood MA, Thornes JE, Fisher PA, Pope FD. Impact of extreme temperatures on ambulance dispatches in London, UK. Environ Res. 2020 Mar;182:109100. doi: 10.1016/j.envres.2019.109100. Epub 2020 Jan 3.
- Chen R, Yin P, Wang L, Liu C, Niu Y, Wang W, Jiang Y, Liu Y, Liu J, Qi J, You J, Kan H, Zhou M. Association between ambient temperature and mortality risk and burden: time series study in 272 main Chinese cities. BMJ. 2018 Oct 31;363:k4306. doi: 10.1136/bmj.k4306.
- Gasparrini A, Guo Y, Hashizume M, Lavigne E, Zanobetti A, Schwartz J, Tobias A, Tong S, Rocklov J, Forsberg B, Leone M, De Sario M, Bell ML, Guo YL, Wu CF, Kan H, Yi SM, de Sousa Zanotti Stagliorio Coelho M, Saldiva PH, Honda Y, Kim H, Armstrong B. Mortality risk attributable to high and low ambient temperature: a multicountry observational study. Lancet. 2015 Jul 25;386(9991):369-75. doi: 10.1016/S0140-6736(14)62114-0. Epub 2015 May 20.
- Ahn J, Bae S, Chung BH, Myong JP, Park MY, Lim YH, Kang MY. Association of summer temperatures and acute kidney injury in South Korea: a case-crossover study. Int J Epidemiol. 2023 Jun 6;52(3):774-782. doi: 10.1093/ije/dyac163.
- Achilleos S, Al-Ozairi E, Alahmad B, Garshick E, Neophytou AM, Bouhamra W, Yassin MF, Koutrakis P. Acute effects of air pollution on mortality: A 17-year analysis in Kuwait. Environ Int. 2019 May;126:476-483. doi: 10.1016/j.envint.2019.01.072. Epub 2019 Mar 4.
- Fiore AM, Naik V, Spracklen DV, Steiner A, Unger N, Prather M, Bergmann D, Cameron-Smith PJ, Cionni I, Collins WJ, Dalsoren S, Eyring V, Folberth GA, Ginoux P, Horowitz LW, Josse B, Lamarque JF, MacKenzie IA, Nagashima T, O'Connor FM, Righi M, Rumbold ST, Shindell DT, Skeie RB, Sudo K, Szopa S, Takemura T, Zeng G. Global air quality and climate. Chem Soc Rev. 2012 Oct 7;41(19):6663-83. doi: 10.1039/c2cs35095e. Epub 2012 Aug 6.
- Chen K, Wolf K, Breitner S, Gasparrini A, Stafoggia M, Samoli E, Andersen ZJ, Bero-Bedada G, Bellander T, Hennig F, Jacquemin B, Pekkanen J, Hampel R, Cyrys J, Peters A, Schneider A; UF&HEALTH Study Group. Two-way effect modifications of air pollution and air temperature on total natural and cardiovascular mortality in eight European urban areas. Environ Int. 2018 Jul;116:186-196. doi: 10.1016/j.envint.2018.04.021. Epub 2018 Apr 22.
- Doherty RM, Heal MR, O'Connor FM. Climate change impacts on human health over Europe through its effect on air quality. Environ Health. 2017 Dec 5;16(Suppl 1):118. doi: 10.1186/s12940-017-0325-2.
- Ebi KL, Capon A, Berry P, Broderick C, de Dear R, Havenith G, Honda Y, Kovats RS, Ma W, Malik A, Morris NB, Nybo L, Seneviratne SI, Vanos J, Jay O. Hot weather and heat extremes: health risks. Lancet. 2021 Aug 21;398(10301):698-708. doi: 10.1016/S0140-6736(21)01208-3.
- Khoshakhlagh AH, Mohammadzadeh M, Gruszecka-Kosowska A, Oikonomou E. Burden of cardiovascular disease attributed to air pollution: a systematic review. Global Health. 2024 May 3;20(1):37. doi: 10.1186/s12992-024-01040-0.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
May 1, 2024
Primary Completion (Actual)
December 31, 2024
Study Completion (Estimated)
March 1, 2025
Study Registration Dates
First Submitted
January 13, 2025
First Submitted That Met QC Criteria
January 23, 2025
First Posted (Actual)
March 25, 2025
Study Record Updates
Last Update Posted (Actual)
March 25, 2025
Last Update Submitted That Met QC Criteria
January 23, 2025
Last Verified
January 1, 2025
More Information
Terms related to this study
Other Study ID Numbers
- QT202146
Drug and device information, study documents
product manufactured in and exported from the U.S.
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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