Comparison of Pain Relief After Arthroscopic Knee Surgery: Adductor Canal Block and Genicular Nerve Block

March 27, 2025 updated by: Muzaffer GENCER, Başakşehir Çam & Sakura City Hospital

Comparison of the Effectiveness of Adductor Canal Block and Genicular Nerve Block on Postoperative Pain and Analgesic Use in Arthroscopic Knee Surgeries

This prospective randomized study aims to compare the analgesic efficacy of Adductor Canal Block (ACB) and Genicular Nerve Block (GNB) groups to relieve postoperative pain in participants between ages of 18-72 undergoing arthroscopic knee surgery under spinal anesthesia. The main question it aims to answer is:

To demonstrate whether Adductor Canal Block or Genicular Nerve Block is more effective in postoperative analgesia in patients undergoing arthroscopic knee surgery based on pain scores, opioid consumption and patient satisfaction.

Arthroscopic knee surgeries cause severe pain especially with movement in the post-operative period. After surgery, the movements of the participants are severely restricted because of pain, which increases the possibility of complications and postpones post-operative knee exercises. In this study, the participants' pain status, VAS score, opioid consumption and patient satisfaction will be measured with a simple scoring system for 24 hours at predetermined time points and then compared. Both types of blocks have pain-relieving effects. This study will only investigate which one is more effective in reducing pain, and there will be no deficiency in relieving the pain of the participants.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Estimated)

68

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

Study Locations

  • Turkey
      • İ̇stanbul, Turkey
        • Recruiting
        • Başakşehir Çam & Sakura City Hospital
        • Contact:
        • Contact:
          • MUZAFFER GENCER
        • Contact:
          • ABDURRAHMAN ENGİN BAYDEMİR
        • Contact:
        • Contact:
          • SİNAN ANAŞ
        • Contact:
          • FUNDA GÜMÜŞ ÖZCAN

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

Yes

Description

Inclusion Criteria:

  • Voluntary willingness to participate in the study.
  • Patients undergoing arthroscopic knee surgery (meniscus, ACL, arthroscopic intervention etc).
  • ASA I-II-III classification.
  • Aged between 18-72 years.
  • No contraindications for regional anesthesia, and deemed suitable for regional anesthesia by the anesthesiologist.
  • Undergoing surgery under spinal anesthesia.
  • Fully oriented and able to cooperate.

Exclusion Criteria:

  • Undergoing surgery under general anesthesia.
  • Chronic analgesic use.
  • Presence of an active infection at the procedure site.
  • Outside the appropriate age range.
  • Inability to comply with postoperative pain/NRS follow-ups.
  • ASA IV-V classification.
  • Non-voluntary patients.
  • Pregnancy.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Double

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: ACB Group
Participants undergoing arthroscopic knee surgery under spinal anestesia receiving pre operative Adductor Canal Block (ACB)
Procedure: Adductor Canal Block (ACB)
Evaluation of postoperative analgesic effectiveness of ACB block in participants undergoing arthroscopic knee surgery under spinal anesthesia.
Active Comparator: Genicular Nerve Block
Participants undergoing arthroscopic knee surgery under spinal anestesia receiving pre operative Genicular Nerve Block (GNB)
Procedure: Genicular Nerve Block (GNB)
Evaluation of postoperative analgesic effectiveness of GNB block in participants undergoing arthroscopic knee surgery under spinal anesthesia.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Effectiveness on Pain Scores (NRS)
Time Frame: Postoperative 24 hours
Postoperative pain assessment is performed using the Numerical Rating Scale (NRS). Participants are asked about their rest pain at Baseline 0, postoperative 1st, 2nd, 4th, 6th, 12th, and 24th hours after applying a preoperative peripheral nerve block. With this method, participants rate their pain with a precise numerical value from 0 to 10. While zero(0) represents "no pain"; Ten (10) represents the opposite end of the pain continuum (e.g., "The most intense pain imaginable," "As intense pain as possible," "Maximum pain").
Postoperative 24 hours

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Amount of rescue analgesia administration
Time Frame: Postoperative 24 hours.
After the surgery all patients will be given 4 times a day Paracetamol 1 gram. Patients who still have pain (NRS 4 or higher) will be given Tramadol 1 mg/kg (maximum 400 mg Tramadol daily). Postoperative 24 hours the amount of the rescue analgesic (Tramadol) will be noted.
Postoperative 24 hours.
Postoperative Blood pressure
Time Frame: Postoperative 24 hours
Participants' blood pressure (mm/hg) will be monitored for 24 hours (Post op 1st, 2nd, 4th, 6th, 12th and 24th hours) postoperatively.
Postoperative 24 hours
Length of hospital stay
Time Frame: Postoperative 14 days
Length of hospital stay will be noted.
Postoperative 14 days
First Time Of Mobilisation/Exercise
Time Frame: Postoperative 24 hours
First time of mobilisation/exercise will be noted.
Postoperative 24 hours
The Time of Rescue Analgesic
Time Frame: Postoperative 24 hours
After the surgery all patients will be given 4 times a day Paracetamol 1 gram. Patients who still have pain (NRS 4 or higher) will be given Tramadol 1 mg/kg (maximum 400 mg Tramadol daily). Postoperative 24 hours the time of the rescue analgesic usage (Tramadol) will be noted.
Postoperative 24 hours
Postoperative heart rate
Time Frame: Postoperative 24 hours
Participants' heart rate (bpm) will be monitored for 24 hours (Post op 1st, 2nd, 4th, 6th, 12th and 24th hours) postoperatively.
Postoperative 24 hours
Postoperative oxygen saturation levels
Time Frame: Postoperative 24 hours
Participants' oxygen saturation levels (spO2 %) will be monitored for 24 hours (Post op 1st, 2nd, 4th, 6th, 12th and 24th hours) postoperatively.
Postoperative 24 hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Başakşehir Çam & Sakura City Hospital

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

March 10, 2025

Primary Completion (Estimated)

August 31, 2025

Study Completion (Estimated)

September 30, 2025

Study Registration Dates

First Submitted

March 21, 2025

First Submitted That Met QC Criteria

March 27, 2025

First Posted (Actual)

April 4, 2025

Study Record Updates

Last Update Posted (Actual)

April 4, 2025

Last Update Submitted That Met QC Criteria

March 27, 2025

Last Verified

March 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • BSH-ANES-SA-01

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

product manufactured in and exported from the U.S.

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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