A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29) (TroFuse-033)

June 1, 2026 updated by: Merck Sharp & Dohme LLC

A Phase 3 Randomized, Open-label, Multicenter Study to Compare the Efficacy and Safety of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone as First-line Maintenance Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (TroFuse-033/GOG-3119/ENGOT-en29)

Researchers are looking for new ways to treat people with proficient mismatch repair (pMMR) endometrial cancer (EC) that is advanced or recurrent.

  • EC is a type of cancer that starts in the tissues inside the uterus (womb)
  • pMMR indicates that certain normal proteins are present in the cancer cells
  • Advanced means the cancer has spread locally or to other parts of the body (metastatic) and cannot be removed with surgery
  • Recurrent means the cancer came back after surgery

Sacituzumab tirumotecan (also known as sac-TMT) and pembrolizumab are the study medicines. Sac-TMT is an antibody drug conjugate (ADC). An ADC attaches to specific targets on cancer cells and delivers treatment to destroy those cells.

The goal of this study is to learn if people who receive sac-TMT with pembrolizumab live longer and without the cancer getting worse compared to people who receive pembrolizumab alone.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

All participants undergo an initial Induction Phase of six cycles, each cycle consisting of pembrolizumab + carboplatin + paclitaxel or docetaxel. Each cycle is three weeks. Participants whose cancer does not progress enter the Maintenance Treatment Phase and are then randomly assigned to pembrolizumab + sac-TMT or pembrolizumab monotherapy. Participants whose cancer does progress will have the possibility to enter the Subsequent Treatment Phase and are then randomly assigned to pembrolizumab + sac-TMT or sac-TMT monotherapy.

Study Type

Interventional

Enrollment (Estimated)

1123

Phase

  • Phase 3

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Locations

  • Argentina
      • CABA, Argentina, C1280AEB
        • Recruiting
        • Hospital Británico de Buenos Aires ( Site 0103)
        • Contact:
          • Study Coordinator
          • Phone Number: +541143096400
      • San Juan, Argentina, J5400EBB
        • Recruiting
        • Instituto San Marcos ( Site 0106)
        • Contact:
          • Study Coordinator
          • Phone Number: +542645836798
    • Buenos Aires
      • Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, C1426ANZ
        • Recruiting
        • Instituto Alexander Fleming ( Site 0105)
        • Contact:
          • Study Coordinator
          • Phone Number: +5491166936669
      • Mar del Plata, Buenos Aires, Argentina, B7600FZO
        • Recruiting
        • Instituto de Investigaciones Clínicas Mar del Plata ( Site 0108)
        • Contact:
          • Study Coordinator
          • Phone Number: +542234963223
    • Buenos Aires F.D.
      • Buenos Aires, Buenos Aires F.D., Argentina, C1426AAL
        • Recruiting
        • Fundación Respirar ( Site 0101)
        • Contact:
          • Study Coordinator
          • Phone Number: +541147815331
  • Australia
    • New South Wales
      • Blacktown, New South Wales, Australia, 2148
        • Recruiting
        • Blacktown Hospital ( Site 0201)
        • Contact:
          • Study Coordinator
          • Phone Number: +610298818000
    • Queensland
      • Brisbane, Queensland, Australia, 4029
        • Recruiting
        • Royal Brisbane and Women's Hospital ( Site 0206)
        • Contact:
          • Study Coordinator
          • Phone Number: 0736478111
    • Victoria
      • Melbourne, Victoria, Australia, 3002
        • Recruiting
        • Epworth Freemasons ( Site 0207)
        • Contact:
          • Study Coordinator
          • Phone Number: 0394171344
    • Western Australia
      • Nedlands, Western Australia, Australia, 6009
        • Recruiting
        • Sir Charles Gairdner Hospital ( Site 0203)
        • Contact:
          • Study Coordinator
          • Phone Number: +610864573333
  • Austria
      • Vienna, Austria, 1090
        • Recruiting
        • Medizinische Universität Wien - Allg. Gynaekologie & Gyn. Onkologie ( Site 0302)
        • Contact:
          • Study Coordinator
          • Phone Number: +4314040061030
    • Styria
      • Graz, Styria, Austria, 8036
        • Recruiting
        • Medizinische Universität Graz-Abteilung für Gynäkologie / Onkologie ( Site 0303)
        • Contact:
          • Study Coordinator
          • Phone Number: +43316 385 81648
    • Tyrol
      • Innsbruck, Tyrol, Austria, 6020
        • Recruiting
        • Medizinische Universitaet Innsbruck-Univ.-Klinik f. Gynäkologie und Geburtshilfe ( Site 0301)
        • Contact:
          • Study Coordinator
          • Phone Number: 435050423051
  • Belgium
    • Bruxelles-Capitale, Region de
      • Brussels, Bruxelles-Capitale, Region de, Belgium, 1000
        • Recruiting
        • CHU Saint-Pierre ( Site 0405)
        • Contact:
          • Study Coordinator
          • Phone Number: +3225353534
    • Oost-Vlaanderen
      • Ghent, Oost-Vlaanderen, Belgium, 9000
        • Recruiting
        • AZ Maria Middelares ( Site 0402)
        • Contact:
          • Study Coordinator
          • Phone Number: +3292469522
    • Vlaams-Brabant
      • Leuven, Vlaams-Brabant, Belgium, 3000
        • Recruiting
        • UZ Leuven ( Site 0401)
        • Contact:
          • Study Coordinator
          • Phone Number: +32 16 342 996
    • Wallonne, Region
      • Charleroi, Wallonne, Region, Belgium, 6060
        • Recruiting
        • Grand Hôpital de Charleroi ( Site 0403)
        • Contact:
          • Study Coordinator
          • Phone Number: +32 60 11 25 00
      • Liège, Wallonne, Region, Belgium, 4000
        • Recruiting
        • CHU de Liege ( Site 0404)
        • Contact:
          • Study Coordinator
          • Phone Number: +3243237688
  • Brazil
      • Rio de Janeiro, Brazil, 20220-410
        • Recruiting
        • Instituto Nacional de Câncer - INCA ( Site 0515)
        • Contact:
          • Study Coordinator
          • Phone Number: +552132072985
    • Goiás
      • Goiânia, Goiás, Brazil, 74605-070
        • Recruiting
        • Hospital Araújo Jorge ( Site 0521)
        • Contact:
          • Study Coordinator
          • Phone Number: +55 62 3243-7260
    • Rio Grande do Norte
      • Natal, Rio Grande do Norte, Brazil, 59062-000
        • Recruiting
        • Liga Norte Riograndense Contra o Câncer ( Site 0523)
        • Contact:
          • Study Coordinator
          • Phone Number: +558440095595
    • Rio Grande do Sul
      • Porto Alegre, Rio Grande do Sul, Brazil, 90610-000
        • Recruiting
        • Hospital São Lucas da PUCRS ( Site 0522)
        • Contact:
          • Study Coordinator
          • Phone Number: +555133203000
    • São Paulo
      • São Paulo, São Paulo, Brazil, 04014-002
        • Recruiting
        • IBCC - Instituto Brasileiro de Controle do Câncer ( Site 0525)
        • Contact:
          • Study Coordinator
          • Phone Number: +551134744278
  • Canada
    • British Columbia
      • Surrey, British Columbia, Canada, V3V 1Z2
        • Recruiting
        • BC Cancer Surrey ( Site 0621)
        • Contact:
          • Study Coordinator
          • Phone Number: 604-930-2098
    • Manitoba
      • Winnipeg, Manitoba, Canada, R3E 0V9
        • Recruiting
        • CancerCare Manitoba ( Site 0617)
        • Contact:
          • Study Coordinator
          • Phone Number: 204-787-4156
    • Newfoundland and Labrador
      • St. John's, Newfoundland and Labrador, Canada, A1B 3V6
        • Recruiting
        • NL Health Services ( Site 0602)
        • Contact:
          • Study Coordinator
          • Phone Number: 709-777-6300
    • Ontario
      • Barrie, Ontario, Canada, L4M 6M2
        • Recruiting
        • Royal Victoria Regional Health Centre ( Site 0615)
        • Contact:
          • Study Coordinator
          • Phone Number: 705 728-9090x66228
      • Sault Ste. Marie, Ontario, Canada, P6B 0A8
        • Recruiting
        • Sault Area Hospital ( Site 0616)
        • Contact:
          • Study Coordinator
          • Phone Number: 705-759-3434x4402
      • Toronto, Ontario, Canada, M5G 2M9
        • Recruiting
        • Princess Margaret Cancer Center ( Site 0609)
        • Contact:
          • Study Coordinator
          • Phone Number: 416-946-4501
      • Toronto, Ontario, Canada, M4N 3M5
        • Recruiting
        • Sunnybrook Research Institute ( Site 0610)
        • Contact:
          • Study Coordinator
          • Phone Number: 416 480-6100
      • Windsor, Ontario, Canada, N8W 1L9
        • Recruiting
        • Windsor Regional Cancer Program ( Site 0614)
        • Contact:
          • Study Coordinator
          • Phone Number: 519-254-5577
    • Quebec
      • Montreal, Quebec, Canada, H2X 0C1
        • Recruiting
        • Centre Hospitalier de l Universite de Montreal - CHUM ( Site 0605)
        • Contact:
          • Study Coordinator
          • Phone Number: 514-890-8000 x30777
      • Montreal, Quebec, Canada, H4A 3J1
        • Recruiting
        • McGill University Health Centre ( Site 0604)
        • Contact:
          • Study Coordinator
          • Phone Number: 5145772241
      • Montreal, Quebec, Canada, H3T 1E2
        • Recruiting
        • Jewish General Hospital ( Site 0606)
        • Contact:
          • Study Coordinator
          • Phone Number: 514-340-8222
      • Sherbrooke, Quebec, Canada, J1H 5N4
        • Recruiting
        • CIUSSS de l Estrie - CHUS - Centre Hosp. Univ. Sherbrooke ( Site 0608)
        • Contact:
          • Study Coordinator
          • Phone Number: 8193461110x12890
  • Chile
    • Region M. de Santiago
      • Santiago, Region M. de Santiago, Chile, 7500653
        • Recruiting
        • Centro de Estudios Clínicos SAGA ( Site 0708)
        • Contact:
          • Study Coordinator
          • Phone Number: +56991612199
      • Santiago, Region M. de Santiago, Chile, 7500921
        • Recruiting
        • FALP ( Site 0702)
        • Contact:
          • Study Coordinator
          • Phone Number: +569 97015608
      • Santiago, Region M. de Santiago, Chile, 8420383
        • Recruiting
        • Bradfordhill ( Site 0703)
        • Contact:
          • Study Coordinator
          • Phone Number: +56229490970
      • Santiago, Region M. de Santiago, Chile, 8330032
        • Recruiting
        • Pontificia Universidad Catolica de Chile ( Site 0705)
        • Contact:
          • Study Coordinator
          • Phone Number: +56942477513
    • Valparaiso
      • Viña del Mar, Valparaiso, Chile, 2520598
        • Recruiting
        • ONCOCENTRO APYS ( Site 0704)
        • Contact:
          • Study Coordinator
          • Phone Number: +56323320850
  • China
    • Anhui
      • Hefei, Anhui, China, 230001
        • Recruiting
        • Anhui Provincial Hospital ( Site 0830)
        • Contact:
          • Study Coordinator
          • Phone Number: 0551-62283666
    • Beijing Municipality
      • Beijing, Beijing Municipality, China, 100044
        • Recruiting
        • Peking University Peoples Hospital ( Site 0845)
        • Contact:
          • Study Coordinator
          • Phone Number: (010) 8832 5988
    • Chongqing Municipality
      • Chongqing, Chongqing Municipality, China, 400030
        • Recruiting
        • Chongqing University Cancer Hospital ( Site 0838)
        • Contact:
          • Study Coordinator
          • Phone Number: 023-65311341
    • Fujian
      • Fuzhou, Fujian, China, 350014
        • Recruiting
        • Fujian Province Cancer Hospital ( Site 0802)
        • Contact:
          • Study Coordinator
          • Phone Number: 0591-83660063
      • Xiamen, Fujian, China, 361003
        • Recruiting
        • The First Affiliated hospital of Xiamen University ( Site 0822)
        • Contact:
          • Study Coordinator
          • Phone Number: 0592-2130789
    • Guangdong
      • Guangzhou, Guangdong, China, 510280
        • Recruiting
        • Zhujiang Hospital of Southern Medical University ( Site 0829)
        • Contact:
          • Study Coordinator
          • Phone Number: +86-020-61643888
      • Guangzhou, Guangdong, China, 510060
        • Recruiting
        • Sun Yat-sen University Cancer Center ( Site 0846)
        • Contact:
          • Study Coordinator
          • Phone Number: +86-020-87343272
      • Guangzhou, Guangdong, China, 510220
        • Recruiting
        • Sun Yat-sen Memorial Hospital, Sun Yat-sen University ( Site 0801)
        • Contact:
          • Study Coordinator
          • Phone Number: 020-81332736
      • Shantou, Guangdong, China, 515041
        • Recruiting
        • Cancer Hospital of Shantou University Medical College ( Site 0827)
        • Contact:
          • Study Coordinator
          • Phone Number: +8675488555844
      • Zhanjiang, Guangdong, China, 524004
        • Recruiting
        • Affiliated Hospital of Guangdong Medical University ( Site 0823)
        • Contact:
          • Study Coordinator
          • Phone Number: 07592369367
    • Guangxi
      • Liuzhou, Guangxi, China, 545006
        • Recruiting
        • Liuzhou People's Hospital ( Site 0831)
        • Contact:
          • Study Coordinator
          • Phone Number: +86772-3612345
      • Nanning, Guangxi, China, 530021
        • Recruiting
        • Guangxi Medical University Affiliated Tumor Hospital. ( Site 0825)
        • Contact:
          • Study Coordinator
          • Phone Number: +8607715778582
    • Heilongjiang
      • Harbin, Heilongjiang, China, 101149
        • Recruiting
        • Harbin Medical University Cancer Hospital ( Site 0850)
        • Contact:
          • Study Coordinator
          • Phone Number: 0451-86298000
    • Henan
      • Zhengzhou, Henan, China, 450014
        • Recruiting
        • The Second Affiliated Hospital of Zhengzhou University ( Site 0833)
        • Contact:
          • Study Coordinator
          • Phone Number: 0371-63974853
      • Zhengzhou, Henan, China, 450008
        • Recruiting
        • Henan Cancer Hospital ( Site 0806)
        • Contact:
          • Study Coordinator
          • Phone Number: 0371-65587418
    • Hubei
      • Wuhan, Hubei, China, 430023
        • Recruiting
        • Wuhan Union Hospital Cancer Center ( Site 0824)
        • Contact:
          • Study Coordinator
          • Phone Number: 027-85726114
    • Hunan
      • Changsha, Hunan, China, 410008
        • Recruiting
        • Xiangya Hospital Central South University ( Site 0821)
        • Contact:
          • Study Coordinator
          • Phone Number: 0731-89753999
      • Changsha, Hunan, China, 410013
        • Recruiting
        • Hunan Cancer Hospital ( Site 0826)
        • Contact:
          • Study Coordinator
          • Phone Number: 0731-88651900
    • Jiangsu
      • Nanjing, Jiangsu, China, 210006
        • Recruiting
        • Nanjing First Hospital ( Site 0828)
        • Contact:
          • Study Coordinator
          • Phone Number: 025-52271000
    • Jiangxi
      • Nanchang, Jiangxi, China, 337000
        • Recruiting
        • Jiangxi Maternal and Child Health Hospital ( Site 0807)
        • Contact:
          • Study Coordinator
          • Phone Number: 0791-82725189
    • Jilin
      • Changchun, Jilin, China, 134021
        • Recruiting
        • The First Hospital Of Jilin University ( Site 0815)
        • Contact:
          • Study Coordinator
          • Phone Number: 0431-88782222
    • Shaanxi
      • Xi'an, Shaanxi, China, 710061
        • Recruiting
        • The First Affiliated Hospital of Xi'an Jiaotong University ( Site 0816)
        • Contact:
          • Study Coordinator
          • Phone Number: 029-85323840
    • Shandong
      • Jinan, Shandong, China, 250117
        • Recruiting
        • Shandong Cancer Hospital ( Site 0803)
        • Contact:
          • Study Coordinator
          • Phone Number: 0531-87984777
    • Shanghai Municipality
      • Shanghai, Shanghai Municipality, China, 200072
        • Recruiting
        • Shanghai Tenth People's Hospital ( Site 0847)
        • Contact:
          • Study Coordinator
          • Phone Number: 021-66300588
      • Shanghai, Shanghai Municipality, China, 200090
        • Recruiting
        • Obstetrics & Gynecology Hospital of Fudan University ( Site 0818)
        • Contact:
          • Study Coordinator
          • Phone Number: 021-33189900
    • Shanxi
      • Taiyuan, Shanxi, China, 030013
        • Recruiting
        • Shanxi Provincial Cancer Hospital ( Site 0843)
        • Contact:
          • Study Coordinator
          • Phone Number: (0351) 465 1590
    • Sichuan
      • Chengdu, Sichuan, China, 610000
        • Recruiting
        • West China Second University Hospital, Sichuan University ( Site 0849)
        • Contact:
          • Study Coordinator
          • Phone Number: 028-85503776
      • Yibin, Sichuan, China, 644000
        • Recruiting
        • The Second People's Hospital of Yibin ( Site 0840)
        • Contact:
          • Study Coordinator
          • Phone Number: 0831 888 8120
    • Yunnan
      • Kunming, Yunnan, China, 650118
        • Recruiting
        • Yunnan Province Cancer Hospital ( Site 0811)
        • Contact:
          • Study Coordinator
          • Phone Number: 0871-68103376
    • Zhejiang
      • Hangzhou, Zhejiang, China, 310006
        • Recruiting
        • The Affiliated Women's Hospital of Zhejiang University ( Site 0834)
        • Contact:
          • Study Coordinator
          • Phone Number: 0571-87061501
      • Linhai, Zhejiang, China, 317000
        • Recruiting
        • Taizhou Hospital of Zhejiang Province ( Site 0809)
        • Contact:
          • Study Coordinator
          • Phone Number: 0576-85199810
      • Wenzhou, Zhejiang, China, 325015
        • Recruiting
        • The First Affiliated Hospital of Wenzhou Medical University ( Site 0805)
        • Contact:
          • Study Coordinator
          • Phone Number: 0577-55579590
  • Colombia
    • Antioquia
      • Medellín, Antioquia, Colombia, 050025
        • Recruiting
        • Instituto de Cancerología S.A.S ( Site 0904)
        • Contact:
          • Study Coordinator
          • Phone Number: +57 3007193097
      • Medellín, Antioquia, Colombia, 050030
        • Recruiting
        • Fundacion Colombiana de Cancerología Clinica Vida ( Site 0905)
        • Contact:
          • Study Coordinator
          • Phone Number: +57 3147362301
    • Bogota D.C.
      • Bogotá, Bogota D.C., Colombia, 110131
        • Recruiting
        • FUNDACION CTIC CENTRO DE TRATAMIENTO E INVESTIGACION SOBRE CANCER LUIS CARLOS SARMIENTO ANGULO ( Site 0902)
        • Contact:
          • Study Coordinator
          • Phone Number: +573183662238
    • Risaralda Department
      • Pereira, Risaralda Department, Colombia, 660001
        • Recruiting
        • Oncologos Del Occidente ( Site 0907)
        • Contact:
          • Study Coordinator
          • Phone Number: +573187715522
  • Czechia
      • Nový Jičín, Czechia, 741 01
        • Recruiting
        • Nemocnice AGEL Novy Jicin a.s. ( Site 1102)
        • Contact:
          • Study Coordinator
          • Phone Number: +420556773111
      • Prague, Czechia, 128 08
        • Recruiting
        • Vseobecna fakultni nemocnice v Praze-Gynekologicko-porodnicka klinika 1.LF a VFN ( Site 1101)
        • Contact:
          • Study Coordinator
          • Phone Number: +420224967451
      • Prague, Czechia, 150 06
        • Recruiting
        • Fakultni nemocnice v Motole-Onkologicka klinika 2. LF UK a FN Motol ( Site 1103)
        • Contact:
          • Study Coordinator
          • Phone Number: +420224434756
    • Ostrava Mesto
      • Ostrava, Ostrava Mesto, Czechia, 708 52
        • Recruiting
        • Fakultni nemocnice Ostrava ( Site 1104)
        • Contact:
          • Study Coordinator
          • Phone Number: +420597371804
  • Denmark
    • Capital Region
      • Copenhagen, Capital Region, Denmark, 2730
        • Recruiting
        • Herlev and Gentofte Hospital ( Site 1202)
        • Contact:
          • Study Coordinator
          • Phone Number: +45 38683868
    • Central Jutland
      • Aarhus, Central Jutland, Denmark, 8200
        • Recruiting
        • Aarhus Universitetshospital, Skejby ( Site 1205)
        • Contact:
          • Study Coordinator
          • Phone Number: +45 78450000
    • North Denmark
      • Aalborg, North Denmark, Denmark, 9000
        • Recruiting
        • Aalborg Universitetshospital, Syd ( Site 1203)
        • Contact:
          • Study Coordinator
          • Phone Number: +45 97660000
    • Region Sjælland
      • Roskilde, Region Sjælland, Denmark, 4000
        • Recruiting
        • Roskilde Sygehus ( Site 1204)
        • Contact:
          • Study Coordinator
          • Phone Number: +45 46323200
  • Finland
    • Northern Savonia
      • Kuopio, Northern Savonia, Finland, 70029
        • Recruiting
        • Kuopion Yliopistollinen Sairaala ( Site 1304)
        • Contact:
          • Study Coordinator
          • Phone Number: 358447172741
    • Pirkanmaa
      • Tampere, Pirkanmaa, Finland, 33520
        • Recruiting
        • Tampereen yliopistollinen sairaala ( Site 1303)
        • Contact:
          • Study Coordinator
          • Phone Number: 358408484029
    • Southwest Finland
      • Turku, Southwest Finland, Finland, 20520
        • Recruiting
        • Turku University Hospital-Department of Obstetrics and Gynecology ( Site 1302)
        • Contact:
          • Study Coordinator
          • Phone Number: 358405465398
    • Uusimaa
      • Helsinki, Uusimaa, Finland, 00029
        • Recruiting
        • Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus) ( Site 1301)
        • Contact:
          • Study Coordinator
          • Phone Number: 358504286945
  • France
      • Paris, France, 75020
        • Recruiting
        • Groupe Hospitalier Diaconesses Croix Saint Simon ( Site 1409)
        • Contact:
          • Study Coordinator
          • Phone Number: +33144741013
      • Paris, France, 75679
        • Recruiting
        • Hopitaux Universitaires Paris Centre-Hopital Cochin ( Site 1411)
        • Contact:
          • Study Coordinator
          • Phone Number: +33158411439
    • Bouches-du-Rhone
      • Marseille, Bouches-du-Rhone, France, 13272
        • Recruiting
        • Institut Paoli Calmettes ( Site 1410)
        • Contact:
          • Study Coordinator
          • Phone Number: +33491223847
    • Calvados
      • Caen, Calvados, France, 14000
        • Recruiting
        • Centre Francois Baclesse ( Site 1412)
        • Contact:
          • Study Coordinator
          • Phone Number: +33231455002
    • Cotes-d Armor
      • Plérin, Cotes-d Armor, France, 22190
        • Recruiting
        • Hôpital Privé Des Côtes d'Armor ( Site 1404)
        • Contact:
          • Study Coordinator
          • Phone Number: +33296752216
    • Gironde
      • Bordeaux, Gironde, France, 33076
        • Recruiting
        • Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest ( Site 1405)
        • Contact:
          • Study Coordinator
          • Phone Number: +33556333333
    • Haute-Garonne
      • Toulouse, Haute-Garonne, France, 31059
        • Recruiting
        • Oncopole Claudius Regaud ( Site 1407)
        • Contact:
          • Study Coordinator
          • Phone Number: +33531155101
    • Hauts-de-Seine
      • Saint-Cloud, Hauts-de-Seine, France, 92210
        • Recruiting
        • Institut Curie - site Saint-Cloud ( Site 1408)
        • Contact:
          • Study Coordinator
          • Phone Number: +33147111549
    • Loire-Atlantique
      • Saint-Herblain, Loire-Atlantique, France, 44800
        • Recruiting
        • Institut De Cancerologie De L Ouest ( Site 1403)
        • Contact:
          • Study Coordinator
          • Phone Number: +33240679900
    • Rhone
      • Lyon, Rhone, France, 69008
        • Recruiting
        • CENTRE LEON BERARD ( Site 1401)
        • Contact:
          • Study Coordinator
          • Phone Number: +33478782716
  • Germany
      • Berlin, Germany, 13353
        • Recruiting
        • Charité Campus Virchow-Klinikum ( Site 1501)
        • Contact:
          • Study Coordinator
          • Phone Number: +49 30 450 564 404
      • Hamburg, Germany, 22307
        • Recruiting
        • Asklepios Kliniken Hamburg ( Site 1509)
        • Contact:
          • Study Coordinator
          • Phone Number: +49401818828138
    • Rhineland-Palatinate
      • Trier, Rhineland-Palatinate, Germany, 54290
        • Recruiting
        • Klinikum Mutterhaus der Borromäerinnen ( Site 1506)
        • Contact:
          • Study Coordinator
          • Phone Number: +4965194782635
    • Saarland
      • Saarbrücken, Saarland, Germany, 66113
        • Recruiting
        • CaritasKlinikum Saarbruecken St. Theresia ( Site 1508)
        • Contact:
          • Study Coordinator
          • Phone Number: +496814061301
    • Saxony
      • Leipzig, Saxony, Germany, 04103
        • Recruiting
        • Universitaetsklinikum Leipzig ( Site 1505)
        • Contact:
          • Study Coordinator
          • Phone Number: +49 341 97 23260
    • Thuringia
      • Jena, Thuringia, Germany, 07747
        • Recruiting
        • Universitaetsklinikum Jena ( Site 1503)
        • Contact:
          • Study Coordinator
          • Phone Number: +49 3641 9329155
  • Greece
    • Attica
      • Athens, Attica, Greece, 115 28
        • Recruiting
        • Alexandra General Hospital of Athens ( Site 1604)
        • Contact:
          • Study Coordinator
          • Phone Number: 0030 2132162543
      • Athens, Attica, Greece, 115 28
        • Recruiting
        • Aretaieio Hospital ( Site 1602)
        • Contact:
          • Study Coordinator
          • Phone Number: 0030 2107286444
      • Chaïdári, Attica, Greece, 124 62
        • Recruiting
        • ATTIKON GENERAL UNIVERSITY HOSPITAL ( Site 1603)
        • Contact:
          • Study Coordinator
          • Phone Number: 0030 2313301848
      • Marousi, Attica, Greece, 151 23
        • Recruiting
        • Iaso Genera ( Site 1605)
        • Contact:
          • Study Coordinator
          • Phone Number: 0030 2107286305
    • Central Macedonia
      • Thessaloniki, Central Macedonia, Greece, 552 36
        • Recruiting
        • Agios Loukas Clinic-DEPARTMENT OF ONCOLOGY ( Site 1601)
        • Contact:
          • Study Coordinator
          • Phone Number: 0030 2310390972
  • Hungary
      • Budapest, Hungary, 1122
        • Recruiting
        • Országos Onkológiai Intézet-Ngyógyászat ( Site 1702)
        • Contact:
          • Study Coordinator
          • Phone Number: +3612248600 Ext 3616
      • Budapest, Hungary, 1088
        • Recruiting
        • Semmelweis Egyetem Szuleszeti es Nogyogyaszati Klinika ( Site 1703)
        • Contact:
          • Study Coordinator
          • Phone Number: 06203522207
      • Debrecen, Hungary, 4032
        • Recruiting
        • Debreceni Egyetem Klinikai Kozpont-Szülészeti és Nőgyógyászati Klinika ( Site 1701)
        • Contact:
          • Study Coordinator
          • Phone Number: 0652255705
  • Ireland
      • Cork, Ireland, T12 DC4A
        • Recruiting
        • Cork University Hospital ( Site 1903)
        • Contact:
          • Study Coordinator
          • Phone Number: +353214920500
      • Dublin, Ireland, D07 R2WY
        • Recruiting
        • Mater Misericordiae University Hospital ( Site 1904)
        • Contact:
          • Study Coordinator
          • Phone Number: +35318034831
      • Dublin, Ireland, D08 E9P6
        • Recruiting
        • St. James's Hospital ( Site 1901)
        • Contact:
          • Study Coordinator
          • Phone Number: +35314103752
  • Israel
      • Haifa, Israel, 3109601
        • Recruiting
        • Rambam Health Care Campus ( Site 2025)
        • Contact:
          • Study Coordinator
          • Phone Number: +972544850251
      • Haifa, Israel, 3436212
        • Recruiting
        • Carmel Hospital ( Site 2023)
        • Contact:
          • Study Coordinator
          • Phone Number: +972544817280
      • Jerusalem, Israel, 9103102
        • Recruiting
        • Shaare Zedek Medical Center ( Site 2020)
        • Contact:
          • Study Coordinator
          • Phone Number: 02-6555424
      • Kfar Saba, Israel, 4428164
        • Recruiting
        • Meir Medical Center. ( Site 2021)
        • Contact:
          • Study Coordinator
          • Phone Number: 97297471575
      • Tel Aviv, Israel, 6423906
        • Recruiting
        • Sourasky Medical Center ( Site 2022)
        • Contact:
          • Study Coordinator
          • Phone Number: 97236973494
  • Italy
      • Catania, Italy, 95126
        • Recruiting
        • Ospedale Cannizzaro ( Site 2103)
        • Contact:
          • Study Coordinator
          • Phone Number: +39-0957262083
      • Florence, Italy, 50134
        • Recruiting
        • Azienda Ospedaliera Universitaria Careggi ( Site 2109)
        • Contact:
          • Study Coordinator
          • Phone Number: +39-0557947908
      • Milan, Italy, 20141
        • Recruiting
        • Istituto Europeo di Oncologia ( Site 2110)
        • Contact:
          • Study Coordinator
          • Phone Number: +39-0294372732
      • Milan, Italy, 20133
        • Recruiting
        • Fondazione IRCCS Istituto Nazionale dei Tumori ( Site 2114)
        • Contact:
          • Study Coordinator
          • Phone Number: +39-0223902719
      • Naples, Italy, 80131
        • Recruiting
        • Istituto Nazionale Tumori IRCCS Fondazione Pascale ( Site 2104)
        • Contact:
          • Study Coordinator
          • Phone Number: +39-0815903637
      • Pisa, Italy, 56126
        • Recruiting
        • Azienda Ospedaliero Universitaria Pisana Ospedale S. Chiara ( Site 2108)
        • Contact:
          • Study Coordinator
          • Phone Number: +39-050992371
      • Roma, Italy, 00 128
        • Recruiting
        • Istituto Nazionale Tumori Regina Elena ( Site 2102)
        • Contact:
          • Study Coordinator
          • Phone Number: +39-0652666771
      • Roma, Italy, 00168
        • Recruiting
        • Fondazione Policlinico Universitario Agostino Gemelli ( Site 2105)
        • Contact:
          • Study Coordinator
          • Phone Number: +39-0630154994
      • Torino, Italy, 10126
        • Recruiting
        • Azienda Ospedaliero-Universitaria Città della Salute e della Scienza di Torino ( Site 2111)
        • Contact:
          • Study Coordinator
          • Phone Number: +39-0113131523
      • Torino, Italy, 10128
        • Recruiting
        • Ospedale Mauriziano ( Site 2101)
        • Contact:
          • Study Coordinator
          • Phone Number: +390115082046
      • Treviso, Italy, 31100
        • Recruiting
        • Ospedale Santa Maria di Ca' Foncello ( Site 2112)
        • Contact:
          • Study Coordinator
          • Phone Number: +39-0422322051
    • Forli-Cesena
      • Meldola, Forli-Cesena, Italy, 47014
        • Recruiting
        • IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori" ( Site 2107)
        • Contact:
          • Study Coordinator
          • Phone Number: +39-0543739968
    • Lombardy
      • Milan, Lombardy, Italy, 20159
        • Recruiting
        • Ospedale Humanitas San Pio X ( Site 2106)
        • Contact:
          • Study Coordinator
          • Phone Number: +39-0269517533
  • Japan
      • Fukuoka, Japan, 811-1395
        • Recruiting
        • National Hospital Organization Kyushu Cancer Center ( Site 2203)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-92-541-3231
      • Fukushima, Japan, 960-1295
        • Recruiting
        • Fukushima Medical University Hospital ( Site 2218)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-24-547-1772
      • Niigata, Japan, 951-8566
        • Recruiting
        • Niigata Cancer Center Hospital ( Site 2210)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-25-266-5111
      • Okayama, Japan, 700-8558
        • Recruiting
        • Okayama University Hospital ( Site 2215)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-86-223-7151
      • Yamagata, Japan, 990-9585
        • Recruiting
        • Yamagata University Hospital ( Site 2219)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-23-628-5840
    • Aichi-ken
      • Nagoya, Aichi-ken, Japan, 464-8681
        • Recruiting
        • Aichi Cancer Center ( Site 2217)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-52-762-6111
    • Ehime
      • Matsuyama, Ehime, Japan, 791-0280
        • Recruiting
        • National Hospital Organization Shikoku Cancer Center ( Site 2206)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-89-999-1111
      • Tōon, Ehime, Japan, 791-0295
        • Recruiting
        • Ehime University Hospital ( Site 2213)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-89-964-5111
    • Fukuoka
      • Kurume, Fukuoka, Japan, 830-0011
        • Recruiting
        • Kurume University Hospital ( Site 2204)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-942-35-3311
    • Gunma
      • Ōta, Gunma, Japan, 373-8550
        • Recruiting
        • Gunma Prefectural Cancer Center ( Site 2202)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-276-38-0771
    • Hokkaido
      • Sapporo, Hokkaido, Japan, 003-0804
        • Recruiting
        • National Hospital Organization Hokkaido Cancer Center ( Site 2212)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-11-811-9111
    • Hyōgo
      • Akashi, Hyōgo, Japan, 673-8558
        • Recruiting
        • Hyogo Cancer Center ( Site 2216)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-78-929-1151
    • Iwate
      • Shiwa-gun, Iwate, Japan, 028-3695
        • Recruiting
        • Iwate Medical University Hospital ( Site 2207)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-19-613-7111
    • Saitama
      • Hidaka, Saitama, Japan, 350-1298
        • Recruiting
        • Saitama Medical University International Medical Center ( Site 2201)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-42-984-4111
    • Shizuoka
      • Sunto-gun, Shizuoka, Japan, 411-8777
        • Recruiting
        • Shizuoka Cancer Center ( Site 2205)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-55-989-5222
    • Tokyo
      • Chūō, Tokyo, Japan, 104-0045
        • Recruiting
        • National Cancer Center Hospital ( Site 2211)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-3-3542-2511
      • Koto, Tokyo, Japan, 135-8550
        • Recruiting
        • Cancer Institute Hospital of JFCR ( Site 2208)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-3-3520-0111
      • Shinjuku, Tokyo, Japan, 160-8582
        • Recruiting
        • Keio University Hospital ( Site 2209)
        • Contact:
          • Study Coordinator
          • Phone Number: +81-3-3353-1211
  • Mexico
      • Aguascalientes, Mexico, 20124
        • Recruiting
        • Centro de Investigación Oncológica Galerías SC ( Site 2405)
        • Contact:
          • Study Coordinator
          • Phone Number: +52 449 689 0593
      • Chihuahua City, Mexico, 31203
        • Recruiting
        • Sitio Clínico UIS Chihuahua (Operadora Unidad de Investigación en Salud de Chihuahua SA de CV) ( Site 2406)
        • Contact:
          • Study Coordinator
          • Phone Number: +526144372837
    • Jalisco
      • Guadalajara, Jalisco, Mexico, 44630
        • Recruiting
        • CIO - Centro de Inmuno-Oncología de Occidente ( Site 2402)
        • Contact:
          • Study Coordinator
          • Phone Number: +523330447001
    • Nuevo León
      • Monterrey, Nuevo León, Mexico, 64460
        • Recruiting
        • Hospital Universitario "Dr. Jose Eleuterio Gonzalez" ( Site 2401)
        • Contact:
          • Study Coordinator
          • Phone Number: +5283464690
    • Oaxaca
      • Oaxaca City, Oaxaca, Mexico, 68020
        • Recruiting
        • Centro de Investigacion Clinica de Oaxaca ( Site 2404)
        • Contact:
          • Study Coordinator
          • Phone Number: +529516035559
  • Netherlands
      • Utrecht, Netherlands, 3584 CX
        • Recruiting
        • Universitair Medisch Centrum Utrecht ( Site 2503)
        • Contact:
          • Study Coordinator
          • Phone Number: +31887556263
    • Limburg
      • Maastricht, Limburg, Netherlands, 6229 HX
        • Recruiting
        • Maastricht UMC+ ( Site 2501)
        • Contact:
          • Study Coordinator
          • Phone Number: +31433876543
  • Norway
      • Oslo, Norway, 0379
        • Recruiting
        • Oslo universitetssykehus, Radiumhospitalet ( Site 2701)
        • Contact:
          • Study Coordinator
          • Phone Number: +4722934404
    • Rogaland
      • Norway, Rogaland, Norway, 4011
        • Recruiting
        • Stavanger Universitetssykehus ( Site 2703)
        • Contact:
          • Study Coordinator
          • Phone Number: +4751518000
    • Troms
      • Tromsø, Troms, Norway, 9038
        • Recruiting
        • Universitetssykehuset Nord-Norge HF ( Site 2702)
        • Contact:
          • Study Coordinator
          • Phone Number: +4777626000
  • Peru
      • Lima, Peru, 15038
        • Recruiting
        • INSTITUTO NACIONAL DE ENFERMEDADES NEOPLASICAS ( Site 2805)
        • Contact:
          • Study Coordinator
          • Phone Number: +5112016500 e3009
    • Lima region
      • Jesus Maria, Lima region, Peru, 15072
        • Recruiting
        • Clínica San Felipe ( Site 2804)
        • Contact:
          • Study Coordinator
          • Phone Number: +51945334003
      • San Isidro, Lima region, Peru, 15038
        • Recruiting
        • IPOR Instituto Peruano de Oncología & Radioterapia ( Site 2803)
        • Contact:
          • Study Coordinator
          • Phone Number: +512241598
  • Poland
    • Greater Poland Voivodeship
      • Poznan, Greater Poland Voivodeship, Poland, 61-866
        • Recruiting
        • Wielkopolskie Centrum Onkologii im. Marii Skłodowskiej-Curie ( Site 3003)
        • Contact:
          • Study Coordinator
          • Phone Number: +48 61 88 50 738
      • Poznan, Greater Poland Voivodeship, Poland, 60-569
        • Recruiting
        • Uniwersytecki Szpital Kliniczny w Poznaniu ( Site 3011)
        • Contact:
          • Study Coordinator
          • Phone Number: +48618549014
    • Masovian Voivodeship
      • Siedlce, Masovian Voivodeship, Poland, 08-110
        • Recruiting
        • Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 3004)
        • Contact:
          • Study Coordinator
          • Phone Number: 256403070
      • Warsaw, Masovian Voivodeship, Poland, 02-781
        • Recruiting
        • Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie ( Site 3002)
        • Contact:
          • Study Coordinator
          • Phone Number: 225462268
    • Podlaskie Voivodeship
      • Bialystok, Podlaskie Voivodeship, Poland, 15-027
        • Recruiting
        • Bialostockie Centrum Onkologii ( Site 3007)
        • Contact:
          • Study Coordinator
          • Phone Number: 48856646732
    • Pomeranian Voivodeship
      • Gdansk, Pomeranian Voivodeship, Poland, 80-214
        • Recruiting
        • Uniwersyteckie Centrum Kliniczne-Klinika Ginekologii, Ginekologii Onkologicznej i Endokrynologii Gi ( Site 3001)
        • Contact:
          • Study Coordinator
          • Phone Number: +48585844050
    • Silesian Voivodeship
      • Gliwice, Silesian Voivodeship, Poland, 44-101
        • Recruiting
        • Narodowy Instytut Onkologii - Oddzial w Gliwicach ( Site 3006)
        • Contact:
          • Study Coordinator
          • Phone Number: +48322788613
    • Świętokrzyskie Voivodeship
      • Kielce, Świętokrzyskie Voivodeship, Poland, 25-734
        • Recruiting
        • Swietokrzyskie Centrum Onkologii. ( Site 3008)
        • Contact:
          • Study Coordinator
          • Phone Number: +48885997850
  • Puerto Rico
      • San Juan, Puerto Rico, 00917
        • Recruiting
        • Puerto Rico Cancer Specialists Clinical Trials ( Site 4201)
        • Contact:
          • Study Coordinator
          • Phone Number: +7879452919
  • Singapore
    • Central Singapore
      • Singapore, Central Singapore, Singapore, 119074
        • Recruiting
        • National University Hospital ( Site 3202)
        • Contact:
          • Study Coordinator
          • Phone Number: 67795555
      • Singapore, Central Singapore, Singapore, 168583
        • Recruiting
        • National Cancer Centre Singapore ( Site 3201)
        • Contact:
          • Study Coordinator
          • Phone Number: +656368000
  • South Korea
      • Seoul, South Korea, 05505
        • Recruiting
        • Asan Medical Center ( Site 3103)
        • Contact:
          • Study Coordinator
          • Phone Number: +82230103748
      • Seoul, South Korea, 03080
        • Recruiting
        • Seoul National University Hospital ( Site 3102)
        • Contact:
          • Study Coordinator
          • Phone Number: +82220723511
      • Seoul, South Korea, 03722
        • Recruiting
        • Severance Hospital, Yonsei University Health System ( Site 3101)
        • Contact:
          • Study Coordinator
          • Phone Number: +82222282250
      • Seoul, South Korea, 06351
        • Recruiting
        • Samsung Medical Center ( Site 3104)
        • Contact:
          • Study Coordinator
          • Phone Number: +82234101382
    • Kyonggi-do
      • Gyeonggi-do, Kyonggi-do, South Korea, 10408
        • Recruiting
        • National Cancer Center ( Site 3106)
        • Contact:
          • Study Coordinator
          • Phone Number: +82319202591
    • Taegu-Kwangyokshi
      • Daegu, Taegu-Kwangyokshi, South Korea, 42601
        • Recruiting
        • Keimyung University Dongsan Hospital ( Site 3105)
        • Contact:
          • Study Coordinator
          • Phone Number: +82532586679
  • Spain
      • Barcelona, Spain, 08035
        • Recruiting
        • Hospital Universitari Vall d''Hebron ( Site 3401)
        • Contact:
          • Study Coordinator
          • Phone Number: +34934894350
      • Córdoba, Spain, 14004
        • Recruiting
        • Hospital Universitario Reina Sofia ( Site 3402)
        • Contact:
          • Study Coordinator
          • Phone Number: +34957011464
      • Madrid, Spain, 28041
        • Recruiting
        • Hospital Universitario 12 de Octubre ( Site 3404)
        • Contact:
          • Study Coordinator
          • Phone Number: +34913908003
      • Madrid, Spain, 28034
        • Recruiting
        • Hospital Universitario Ramon y Cajal ( Site 3403)
        • Contact:
          • Study Coordinator
          • Phone Number: +34913368263
      • Madrid, Spain, 28046
        • Recruiting
        • Hospital Universitario La Paz ( Site 3406)
        • Contact:
          • Study Coordinator
          • Phone Number: +34679927508
      • Valencia, Spain, 46009
        • Recruiting
        • Fundación Instituto Valenciano de Oncología ( Site 3405)
        • Contact:
          • Study Coordinator
          • Phone Number: +34961114249
    • Barcelona
      • L'Hospitalet de Llobregat, Barcelona, Spain, 08908
        • Recruiting
        • Institut Català d'Oncologia - L'Hospitalet ( Site 3408)
        • Contact:
          • Study Coordinator
          • Phone Number: +34932607744
    • Gerona
      • Girona, Gerona, Spain, 17007
        • Recruiting
        • Institut Català d'Oncologia (ICO) - Girona ( Site 3407)
        • Contact:
          • Study Coordinator
          • Phone Number: +34972225834
  • Sweden
    • Skåne County
      • Lund, Skåne County, Sweden, 22185
        • Recruiting
        • Skånes Universitetssjukhus Lund ( Site 3502)
        • Contact:
          • Study Coordinator
          • Phone Number: +46171000
    • Uppsala County
      • Uppsala, Uppsala County, Sweden, 751 85
        • Recruiting
        • Akademiska Sjukhuset ( Site 3501)
        • Contact:
          • Study Coordinator
          • Phone Number: 0186110000
  • Taiwan
      • Taichung, Taiwan, 40705
        • Recruiting
        • Taichung Veterans General Hospital ( Site 3703)
        • Contact:
          • Study Coordinator
          • Phone Number: 886-4-23592525
      • Tainan, Taiwan, 704
        • Recruiting
        • National Cheng Kung University Hospital ( Site 3702)
        • Contact:
          • Study Coordinator
          • Phone Number: +88662353535
      • Taipei, Taiwan, 10002
        • Recruiting
        • National Taiwan University Hospital ( Site 3701)
        • Contact:
          • Study Coordinator
          • Phone Number: 886-2-23123456
      • Taipei, Taiwan, 10449
        • Recruiting
        • Mackay Memorial Hospital ( Site 3704)
        • Contact:
          • Study Coordinator
          • Phone Number: +886 975835334
      • Taoyuan, Taiwan, 333
        • Recruiting
        • Linkou Chang Gung Memorial Hospital ( Site 3705)
        • Contact:
          • Study Coordinator
          • Phone Number: 886-3-3281200
  • Thailand
      • Chiang Mai, Thailand, 50200
        • Recruiting
        • Maharaj Nakorn Chiang Mai Hospital ( Site 3804)
        • Contact:
          • Study Coordinator
          • Phone Number: +66804964292
      • Khon Kaen, Thailand, 40002
        • Recruiting
        • Faculty of Medicine - Khon Kaen University ( Site 3803)
        • Contact:
          • Study Coordinator
          • Phone Number: +6643363029
    • Bangkok
      • Bangkok, Bangkok, Thailand, 10700
        • Recruiting
        • Faculty of Medicine Siriraj Hospital ( Site 3801)
        • Contact:
          • Study Coordinator
          • Phone Number: +6624141914
      • Bangkok, Bangkok, Thailand, 10400
        • Recruiting
        • Ramathibodi Hospital. ( Site 3802)
        • Contact:
          • Study Coordinator
          • Phone Number: +66822316889
  • United Kingdom
      • Leicester, United Kingdom, LE1 5WW
        • Recruiting
        • Leicester Royal Infirmary ( Site 4008)
        • Contact:
          • Study Coordinator
          • Phone Number: +443003031573
      • Maidstone, United Kingdom, ME16 9QQ
        • Recruiting
        • Maidstone Hospital ( Site 4007)
        • Contact:
          • Study Coordinator
          • Phone Number: +441622729000
      • Manchester, United Kingdom, M20 4BX
        • Recruiting
        • The Christie NHS Foundation Trust ( Site 4003)
        • Contact:
          • Study Coordinator
          • Phone Number: +441614463000
    • Brighton And Hove
      • East Sussex, Brighton And Hove, United Kingdom, BN2 1ES
        • Recruiting
        • University Hospitals Sussex NHS Foundation Trust ( Site 4011)
        • Contact:
          • Study Coordinator
          • Phone Number: 01273696955
    • Cambridgeshire
      • Cambridge, Cambridgeshire, United Kingdom, CB2 0QQ
        • Recruiting
        • Addenbrookes Hospital ( Site 4002)
        • Contact:
          • Study Coordinator
          • Phone Number: +441223805000
    • London, City of
      • London, London, City of, United Kingdom, SW3 6JJ
        • Recruiting
        • ROYAL MARSDEN HOSPITAL (CHELSEA) ( Site 4006)
        • Contact:
          • Study Coordinator
          • Phone Number: 02073528171
      • London, London, City of, United Kingdom, W12 0HS
        • Recruiting
        • Hammersmith Hospital ( Site 4010)
        • Contact:
          • Study Coordinator
          • Phone Number: +443000330333
      • London, London, City of, United Kingdom, NW1 2PG
        • Recruiting
        • University College London Hospital ( Site 4001)
        • Contact:
          • Study Coordinator
          • Phone Number: +442034477807
    • Midlothian
      • Edinburgh, Midlothian, United Kingdom, EH4 2XU
        • Recruiting
        • Western General Hospital ( Site 4012)
        • Contact:
          • Study Coordinator
          • Phone Number: +441315371000
    • Surrey
      • London, Surrey, United Kingdom, SM3 5PT
        • Recruiting
        • Royal Marsden Hospital (Sutton) ( Site 4005)
        • Contact:
          • Study Coordinator
          • Phone Number: 02073528171
  • United States
    • Alabama
      • Mobile, Alabama, United States, 36604
        • Recruiting
        • University of South Alabama, Mitchell Cancer Institute ( Site 6033)
        • Contact:
          • Study Coordinator
          • Phone Number: 251-665-8000
    • Alaska
      • Anchorage, Alaska, United States, 99508
        • Recruiting
        • Alaska Women's Cancer Care ( Site 6036)
        • Contact:
          • Study Coordinator
          • Phone Number: 907-562-4673
    • California
      • Orange, California, United States, 92868
        • Recruiting
        • University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 6020)
        • Contact:
          • Study Coordinator
          • Phone Number: 949-813-1517
      • Walnut Creek, California, United States, 94598
        • Recruiting
        • John Muir Health Cancer Center ( Site 6028)
        • Contact:
          • Study Coordinator
          • Phone Number: 925-674-2580
    • Connecticut
      • New Haven, Connecticut, United States, 06510
        • Recruiting
        • Yale University School of Medicine ( Site 6009)
        • Contact:
          • Study Coordinator
          • Phone Number: 203-737-4450
    • District of Columbia
      • Washington D.C., District of Columbia, United States, 20010
        • Recruiting
        • MedStar Washington Hospital Center ( Site 5005)
        • Contact:
          • Study Coordinator
          • Phone Number: 202-877-7000
    • Florida
      • Fort Myers, Florida, United States, 33901
        • Recruiting
        • Florida Cancer Specialists - South ( Site 7003)
        • Contact:
          • Study Coordinator
          • Phone Number: 239-274-9930
      • Gainesville, Florida, United States, 32608
        • Recruiting
        • UF Health Davis Cancer Pavilion and Shands Med Plaza ( Site 6026)
        • Contact:
          • Study Coordinator
          • Phone Number: 352-273-7832
      • Miami Beach, Florida, United States, 33140
        • Recruiting
        • Mount Sinai Braman Comprehensive Cancer Center ( Site 6031)
        • Contact:
          • Study Coordinator
          • Phone Number: 305-674-2625
      • Orlando, Florida, United States, 32804
        • Recruiting
        • AdventHealth Orlando-AdventHealth Medical Group Gynecological Oncology ( Site 6002)
        • Contact:
          • Study Coordinator
          • Phone Number: 407-609-3462
      • St. Petersburg, Florida, United States, 33701
        • Recruiting
        • Florida Cancer Specialists ( Site 7002)
        • Contact:
          • Study Coordinator
          • Phone Number: 727-522-0558
      • West Palm Beach, Florida, United States, 33401
        • Recruiting
        • Florida Cancer Specialists East ( Site 7001)
        • Contact:
          • Study Coordinator
          • Phone Number: 561-366-4100
    • Georgia
      • Savannah, Georgia, United States, 31405
        • Recruiting
        • St. Joseph's/Candler Health System ( Site 6021)
        • Contact:
          • Study Coordinator
          • Phone Number: 912-819-5704
    • Illinois
      • Chicago, Illinois, United States, 60637
        • Recruiting
        • University of Chicago Medical Center ( Site 5002)
        • Contact:
          • Study Coordinator
          • Phone Number: 773-702-1220
    • Indiana
      • Fort Wayne, Indiana, United States, 46845
        • Recruiting
        • Parkview Research Center ( Site 6008)
        • Contact:
          • Study Coordinator
          • Phone Number: 800-724-8326
    • Louisiana
      • Covington, Louisiana, United States, 70433
        • Recruiting
        • Women's Cancer Care ( Site 6010)
        • Contact:
          • Study Coordinator
          • Phone Number: 985-317-6005
      • Shreveport, Louisiana, United States, 71103
        • Recruiting
        • TRIALS 365 ( Site 6005)
        • Contact:
          • Study Coordinator
          • Phone Number: 318-408-1198
    • Maine
      • Scarborough, Maine, United States, 04074
        • Recruiting
        • Maine Medical Center - Scarborough Campus ( Site 6042)
        • Contact:
          • Study Coordinator
          • Phone Number: 207-396-7089
    • Massachusetts
      • Boston, Massachusetts, United States, 02111
        • Recruiting
        • Tufts Medical Center ( Site 6052)
        • Contact:
          • Study Coordinator
          • Phone Number: 617-636-2616
    • Minnesota
      • Minneapolis, Minnesota, United States, 55404
        • Recruiting
        • Minnesota Oncology Hematology, PA ( Site 8003)
        • Contact:
          • Study Coordinator
          • Phone Number: 817-837-8660
    • Mississippi
      • Jackson, Mississippi, United States, 39216
        • Recruiting
        • St. Dominic's Hospital ( Site 5004)
        • Contact:
          • Study Coordinator
          • Phone Number: 601-200-4970
    • New Jersey
      • Teaneck, New Jersey, United States, 07666
        • Recruiting
        • Holy Name Medical Center ( Site 6011)
        • Contact:
          • Study Coordinator
          • Phone Number: 201-227-6200
    • New Mexico
      • Albuquerque, New Mexico, United States, 87131
        • Recruiting
        • University of New Mexico Comprehensive Cancer Center ( Site 6046)
        • Contact:
          • Study Coordinator
          • Phone Number: 505-272-4946
    • New York
      • Mineola, New York, United States, 11501
        • Recruiting
        • Perlmutter Cancer Center at NYU Langone Hospital - Long Island ( Site 6055)
        • Contact:
          • Study Coordinator
          • Phone Number: 516-708-4821
      • New York, New York, United States, 10016
        • Recruiting
        • Laura and Isaac Perlmutter Cancer Center at NYU Langone ( Site 6004)
        • Contact:
          • Study Coordinator
          • Phone Number: 212-731-6455
    • North Carolina
      • Durham, North Carolina, United States, 27710
        • Recruiting
        • Duke Cancer Institute ( Site 6049)
        • Contact:
          • Study Coordinator
          • Phone Number: 919-684-3780
      • Pinehurst, North Carolina, United States, 28374
        • Recruiting
        • FirstHealth of the Carolinas ( Site 6037)
        • Contact:
          • Study Coordinator
          • Phone Number: 910-715-8684
    • Ohio
      • Centerville, Ohio, United States, 45459
        • Recruiting
        • Miami Valley Hospital South ( Site 6014)
        • Contact:
          • Study Coordinator
          • Phone Number: 937-438-7800
      • Columbus, Ohio, United States, 43210
        • Recruiting
        • The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 6007)
        • Contact:
          • Study Coordinator
          • Phone Number: 614-293-9337
      • Kettering, Ohio, United States, 45429
        • Recruiting
        • Kettering Health Main Campus-Kettering Health Cancer Center ( Site 5001)
        • Contact:
          • Study Coordinator
          • Phone Number: 937-395-6017
    • Oklahoma
      • Tulsa, Oklahoma, United States, 74146
        • Recruiting
        • Oklahoma Cancer Specialists and Research Institute, LLC ( Site 6047)
        • Contact:
          • Study Coordinator
          • Phone Number: 918-505-3200
    • Oregon
      • Eugene, Oregon, United States, 97401
        • Recruiting
        • Oncology Associates of Oregon, P.C. ( Site 8005)
        • Contact:
          • Study Coordinator
          • Phone Number: 541-736-3385
    • Pennsylvania
      • Bethlehem, Pennsylvania, United States, 18015
        • Recruiting
        • St. Luke's University Health Network ( Site 6041)
        • Contact:
          • Study Coordinator
          • Phone Number: 484-503-4673
      • Philadelphia, Pennsylvania, United States, 19104
        • Recruiting
        • Hospital of the University of Pennsylvania ( Site 5007)
        • Contact:
          • Study Coordinator
          • Phone Number: 215-662-2487
      • Philadelphia, Pennsylvania, United States, 19104
        • Completed
        • Hospital of the University of Pennsylvania ( Site 6023)
      • Pittsburgh, Pennsylvania, United States, 15224
        • Recruiting
        • AHN West Penn Hospital ( Site 6006)
        • Contact:
          • Study Coordinator
          • Phone Number: 412-578-1116
    • Rhode Island
      • Providence, Rhode Island, United States, 02905
        • Recruiting
        • Women & Infants Hospital ( Site 5003)
        • Contact:
          • Study Coordinator
          • Phone Number: 401-453-7520
    • Texas
      • Fort Worth, Texas, United States, 76104
        • Recruiting
        • Texas Oncology - DFW ( Site 8004)
        • Contact:
          • Study Coordinator
          • Phone Number: 817-413-1500
      • Houston, Texas, United States, 77030
        • Recruiting
        • Houston Methodist Hospital ( Site 6057)
        • Contact:
          • Study Coordinator
          • Phone Number: 713-441-6616
      • San Antonio, Texas, United States, 78240
        • Recruiting
        • Texas Oncology-San Antonio Medical Center ( Site 8001)
        • Contact:
          • Study Coordinator
          • Phone Number: 210-595-5300
      • Tyler, Texas, United States, 75702
        • Recruiting
        • Texas Oncology - Northeast Texas ( Site 8002)
        • Contact:
          • Study Coordinator
          • Phone Number: 903-579-9800
      • Webster, Texas, United States, 77598
        • Recruiting
        • Texas Oncology - Gulf Coast ( Site 8006)
        • Contact:
          • Study Coordinator
          • Phone Number: 281-332-7505
    • Virginia
      • Fairfax, Virginia, United States, 22031
        • Recruiting
        • Inova Schar Cancer Institute ( Site 6003)
        • Contact:
          • Study Coordinator
          • Phone Number: 571-472-4724
      • Richmond, Virginia, United States, 23219
        • Recruiting
        • VCU Health Adult Outpatient Pavillion ( Site 5000)
        • Contact:
          • Study Coordinator
          • Phone Number: 804-628-4368

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Key inclusion criteria include but are not limited to:

  • Has a histologically confirmed diagnosis of primary advanced or recurrent endometrial carcinoma that has been confirmed as proficient mismatch repair (pMMR)
  • Has radiographically evaluable disease, with measurable Stage III or either measurable or non-measurable Stage IV or recurrent disease per Response Evaluation Criteria In Solid Tumors version 1.1 (RECIST 1.1), as assessed by the investigator
  • Has received no prior systemic therapy for endometrial carcinoma except the following conditions as pre-specified by the protocol: 1 prior line of systemic platinum-based adjuvant and/or neoadjuvant chemotherapy in the setting of curative-intent, prior radiation with or without radiosensitizing chemotherapy if >2 weeks before the start of induction treatment, or prior hormonal therapy for treatment of endometrial carcinoma that was discontinued ≥1 week before the start of induction treatment

Key exclusion criteria include but are not limited to:

  • Has carcinosarcoma, neuroendocrine tumors or endometrial sarcoma, including stromal sarcoma, leiomyosarcoma, adenosarcoma, or other types of sarcomas
  • Has endometrial carcinoma of any histology that is mismatch repair deficient (dMMR)
  • Is a candidate for debulking surgery resulting in complete removal of all tumor and no evidence of radiological disease following surgery, or curative-intent radiotherapy at the time of enrollment
  • Has a history of documented severe dry eye syndrome, severe Meibomian gland disease and/or blepharitis, or severe corneal disease that prevents/delays corneal healing
  • Has active inflammatory bowel disease requiring immunosuppressive medication or previous history of inflammatory bowel disease
  • Has uncontrolled, significant cardiovascular disease or cerebrovascular disease
  • Human Immunodeficiency Virus-infected participants with a history of Kaposi's sarcoma and/or Multicentric Castleman's Disease
  • Received prior therapy in any setting with any of the following: anti-programmed cell death 1 protein, anti-programmed cell death ligand 1, anti-programmed cell death ligand 2 agent, or with an agent directed to another stimulatory or coinhibitory T-cell receptor; trophoblast cell surface antigen 2-targeted antibody drug conjugate; or topoisomerase I inhibitor-containing antibody drug conjugate

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Maintenance Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan

During the Induction Phase, participants receive pembrolizumab 200 mg, carboplatin area under the curve (AUC) 5 (mg/mL/min), and paclitaxel 175 mg/m^2 or docetaxel 75 mg/m^2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months).

During the Maintenance Treatment Phase, participants receive sac-TMT 4 mg/kg on Days 1, 15, and 29 of each 6-week cycle and pembrolizumab 400 mg on Day 1 of each 6-week cycle for up to 14 cycles (up to approximately 19 months).
Biological: Pembrolizumab
Intravenous (IV) Infusion
Other Names:
  • MK-3475
  • SCH 900475
  • KEYTRUDA®
Drug: Carboplatin
During the Induction Phase, participants receive carboplatin AUC 5 (mg/mL/min) on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.
Biological: Sacituzumab Tirumotecan
IV Infusion
Other Names:
  • SKB264
  • MK-2870
  • sac-TMT
Drug: Paclitaxel
During the Induction Phase, participants receive paclitaxel 175 mg/m^2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.
Drug: Docetaxel
During the Induction Phase, participants may receive docetaxel (in place of paclitaxel) 75 mg/m^2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.
Active Comparator: Maintenance Treatment Arm B: Pembrolizumab Monotherapy

During the Induction Phase, participants receive pembrolizumab 200 mg, carboplatin AUC 5 (mg/mL/min), and paclitaxel 175 mg/m^2 or docetaxel 75 mg/m^2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months).

During the Maintenance Treatment Phase, participants receive pembrolizumab 400 mg on Day 1 of each 6-week cycle for up to 14 cycles (up to approximately 19 months).
Biological: Pembrolizumab
Intravenous (IV) Infusion
Other Names:
  • MK-3475
  • SCH 900475
  • KEYTRUDA®
Drug: Carboplatin
During the Induction Phase, participants receive carboplatin AUC 5 (mg/mL/min) on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.
Drug: Paclitaxel
During the Induction Phase, participants receive paclitaxel 175 mg/m^2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.
Drug: Docetaxel
During the Induction Phase, participants may receive docetaxel (in place of paclitaxel) 75 mg/m^2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.
Experimental: Subsequent Treatment Arm A: Pembrolizumab + Sacituzumab Tirumotecan

During the Induction Phase, participants receive pembrolizumab 200 mg, carboplatin AUC 5 (mg/mL/min), and paclitaxel 175 mg/m^2 or docetaxel 75 mg/m^2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months).

During the Subsequent Treatment Phase, participants receive sac-TMT 4 mg/kg on Days 1, 15, and 29 of each 6-week cycle until discontinuation criteria is met and pembrolizumab 400 mg on Day 1 of each 6-week cycle for up to 14 cycles (up to approximately 19 months).
Biological: Pembrolizumab
Intravenous (IV) Infusion
Other Names:
  • MK-3475
  • SCH 900475
  • KEYTRUDA®
Drug: Carboplatin
During the Induction Phase, participants receive carboplatin AUC 5 (mg/mL/min) on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.
Biological: Sacituzumab Tirumotecan
IV Infusion
Other Names:
  • SKB264
  • MK-2870
  • sac-TMT
Drug: Paclitaxel
During the Induction Phase, participants receive paclitaxel 175 mg/m^2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.
Drug: Docetaxel
During the Induction Phase, participants may receive docetaxel (in place of paclitaxel) 75 mg/m^2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.
Active Comparator: Subsequent Treatment Arm B: Sacituzumab Tirumotecan Monotherapy

During the Induction Phase, participants receive pembrolizumab 200 mg, carboplatin AUC 5 (mg/mL/min), and paclitaxel 175 mg/m^2 or docetaxel 75 mg/m^2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months).

During the Subsequent Treatment Phase, participants receive sac-TMT 4 mg/kg on Days 1, 15, and 29 of each 6-week cycle until discontinuation criteria is met.
Drug: Carboplatin
During the Induction Phase, participants receive carboplatin AUC 5 (mg/mL/min) on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.
Biological: Sacituzumab Tirumotecan
IV Infusion
Other Names:
  • SKB264
  • MK-2870
  • sac-TMT
Drug: Paclitaxel
During the Induction Phase, participants receive paclitaxel 175 mg/m^2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.
Drug: Docetaxel
During the Induction Phase, participants may receive docetaxel (in place of paclitaxel) 75 mg/m^2 on Day 1 of each 3-week cycle for 6 cycles (up to approximately 4 months) via IV infusion.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Maintenance Treatment: Progression-Free Survival (PFS)
Time Frame: Up to approximately 44 months
PFS is defined as the time from randomization to the first documented progressive disease (PD) or death due to any cause, whichever occurs first as assessed by Response Criteria in Solid Tumors Version 1.1 (RECIST 1.1) as evaluated by the blinded independent central review (BICR). PD is defined as ≥20% increase in the sum of diameters of target lesions. In addition to the relative increase of 20%, the sum must also demonstrate an absolute increase of ≥5 mm. The appearance of one or more new lesions is also considered PD.
Up to approximately 44 months
Maintenance Treatment: Overall Survival (OS)
Time Frame: Up to approximately 54 months
OS is defined as time from randomization to death due to any cause.
Up to approximately 54 months

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Maintenance Treatment: Progression-Free Survival 2 (PFS2) as Assessed by Investigator
Time Frame: Up to approximately 54 months
PFS2 is defined as the time from randomization to the documented subsequent objective disease progression after initiation of new anticancer therapy or death due to any cause, whichever occurs first. PFS2 as assessed by the investigator will be presented.
Up to approximately 54 months
Maintenance Treatment: Number of Participants Who Experience One or More Adverse Events (AEs)
Time Frame: Up to approximately 27 months
An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention.
Up to approximately 27 months
Maintenance Treatment: Number of Participants Who Discontinue Study Intervention Due to an AE
Time Frame: Up to approximately 24 months
An AE is any untoward medical occurrence in a clinical study participant, temporally associated with the use of study intervention, whether or not considered related to the study intervention.
Up to approximately 24 months
Maintenance Treatment: Change from baseline in EORTC QLQ-C30 Physical Functioning (Items 1-5) Combined Score
Time Frame: Baseline and up to approximately 24 months
EORTC QLQ-C30 is a 30-item scale to assess the overall quality of life of cancer patients. The physical functioning score is based on participant responses to questions scored on a 4-point scale (1 = 'Not at All' to 4 = 'Very Much'). Higher scores indicate better physical functioning. The change from baseline in EORTC QLQ-C30 Physical Functioning (Items 1-5) combined score will be presented.
Baseline and up to approximately 24 months
Maintenance Treatment: Change from baseline in EORTC QLQ-C30 Role Functioning (Items 6 and 7) Combined Score
Time Frame: Baseline and up to approximately 24 months
EORTC QLQ-C30 is a 30-item scale to assess the overall quality of life of cancer patients. The role functioning score is based on participant responses to questions scored on a 4-point scale (1 = 'Not at All' to 4 = 'Very Much'). Higher scores indicate better role functioning. The change from baseline in EORTC QLQ-C30 Role Functioning (Items 6 and 7) combined score will be presented.
Baseline and up to approximately 24 months
Maintenance Treatment: Change from baseline in European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire Core 30 (EORTC QLQ-C30) Global Health Status/Quality of Life (Items 29 and 30) Mean Score
Time Frame: Baseline and up to approximately 24 months
EORTC QLQ-C30 is a 30-item scale to assess the overall quality of life of cancer patients. Participant responses to the questions "How would you rate your overall health during the past week?" and "How would you rate your overall quality of life during the past week?" are scored on a 7- point scale (1= Very poor to 7=Excellent). Using linear transformation, raw scores are standardized, so that scores range from 0 to 100. A higher score indicates a better overall health status. The change from baseline in EORTC QLQ-C30 Global Health Status/Quality of Life score (Items 29 and 30) will be presented.
Baseline and up to approximately 24 months
Maintenance Treatment: Change from baseline in EORTC QLQ-EN24 Symptom Score
Time Frame: Baseline and up to approximately 24 months
The EORTC QLQ-EN24 is a 24-item questionnaire developed to be used in conjunction with the EORTC-QLQ-C30 to assess the quality of life of endometrial cancer patients. Participant responses are scored on a 4-point scale (1=not at all to 4=very much). A higher score reflects greater symptom severity. The change from baseline in EORTC QLQ-EN24 back and pelvis pain score will be presented.
Baseline and up to approximately 24 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Merck Sharp & Dohme LLC

Investigators

  • Study Director: Medical Director, Merck Sharp & Dohme LLC

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 21, 2025

Primary Completion (Estimated)

May 24, 2032

Study Completion (Estimated)

May 24, 2032

Study Registration Dates

First Submitted

April 23, 2025

First Submitted That Met QC Criteria

April 23, 2025

First Posted (Actual)

May 1, 2025

Study Record Updates

Last Update Posted (Actual)

June 3, 2026

Last Update Submitted That Met QC Criteria

June 1, 2026

Last Verified

June 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2870-033
  • U1111-1315-0794 (Registry Identifier: UTN)
  • GOG-3119 (Other Identifier: Gynecologic Oncology Group)
  • ENGOT-en29 (Other Identifier: European Network for Gynaecological Oncological Trial groups)
  • TroFuse-033 (Other Identifier: MSD)
  • 2024-519331-42-00 (Registry Identifier: EU CT)
  • jRCT2011250020 (Registry Identifier: Japan Registry of Clinical Trial (jRCT))

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

IPD Plan Description

https://trialstransparency.msdclinicaltrials.com/pdf/ProcedureAccessClinicalTrialData.pdf

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

Yes

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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