- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT07023146
- Original Trial
Effects of Different Power Training Intensities in Older Adults
Adaptations Due to Different Intensities of Power Training on Neuromuscular Performance, Muscle Thickness and Functional Capacity in Elderly People: A Randomized Clinical Trial
Study Overview
Status
Study Type
Enrollment (Estimated)
Phase
- Not Applicable
Contacts and Locations
Study Locations
-
-
RS
-
Porto Alegre, RS, Brazil, 91410-070
- Universidade Federal do Rio Grande do Sul (UFRGS)
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
- Adult
- Older Adult
Accepts Healthy Volunteers
Description
Inclusion criteria:
- Age 60 years or older
- No participation in regular and systematic resistance training in the last three months
- No absolute or relative contraindications to exercise
- No musculoskeletal injuries that could interfere with training and assessments
Exclusion criteria:
- Use of steroids, nutritional supplements, or ergogenic substances
- Failure to complete all study phases
- Failure to complete more than 80% of the training sessions (32 sessions)
Study Plan
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Triple
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
|---|---|
|
Active Comparator: Low to moderate intensity (PTLM; 40-60% of 1-repetition maximum [1RM])
Power training performed at maximum velocity in the concentric phase with lower to moderate intensity
|
Power training performed at maximum velocity in the concentric phase with lower to moderate intensity
Other Names:
|
|
Active Comparator: Moderate to high intensity (PTMH; 65-80% % of 1-repetition maximum [1RM])
Power training performed at maximum velocity in the concentric phase with moderate to high intensity
|
Power training performed at maximum velocity in the concentric phase with moderate to high intensity
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Muscle Power
Time Frame: Pre- and post-intervention (16 weeks of training)
|
The power output during strength exercises is assessed using an encoder linear at two different intensities: 30% and 70% of 1RM in leg extension and leg press 45. Power output is the ability to generate force quickly and is a key measure of explosive strength. These tests are performed using different resistance levels to assess power across a range of intensities. Measurement Tool: Encoder linear (linear encoder or velocity-based device) Scale: Power output in watts (W) Higher scores indicate better power performance at each intensity. |
Pre- and post-intervention (16 weeks of training)
|
|
Muscle Strength
Time Frame: Pre- and post-intervention (16 weeks of training)
|
Muscle strength is the ability of a muscle or muscle group to generate force against resistance. It reflects the maximum force that can be produced in a single effort and is essential for daily activities and overall physical function. One Repetition Maximum (1RM) is used to quantify maximal strength. Measurement Tool: 1RM testing Scale: 1RM (measured in kg) Higher scores indicate better strength performance. |
Pre- and post-intervention (16 weeks of training)
|
|
Rate of Force Development
Time Frame: Pre- and post-intervention (16 weeks of training)
|
Rate of force development refers to the speed at which force is generated by a muscle or muscle group. It is a critical measure of neuromuscular performance, especially in activities that require explosive strength or rapid reactions. RFD is measured during maximal voluntary contractions. Measurement Tool: Load Cell Scale: Measured in Newtons per second (N/s) Higher scores indicate better neuromuscular performance. |
Pre- and post-intervention (16 weeks of training)
|
Secondary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
|---|---|---|
|
Functional Capacity
Time Frame: Pre- and post-intervention (16 weeks of training)
|
Functional capacity refers to an individual's ability to perform activities required for daily living, such as walking, climbing stairs, or carrying objects. It reflects overall physical function and is often used to assess health status, particularly in older adults or clinical populations. The following tests were selected to assess functional capacity: Stair Climbing Test Scale: Total time to climb and descend a predetermined number of stairs. Shorter time indicates better performance. Timed Up and Go (TUG) Scale: Total time in seconds. Shorter time indicates better mobility and agility. 6-Meter Walk Speed Test Scale: Total time to walk 6 meters (seconds). Shorter time indicates faster walking speed. Sit-to-Stand Test (5 times) Scale: Total time to complete the 5 repetitions. Shorter time indicates better muscle strength and functional capacity. |
Pre- and post-intervention (16 weeks of training)
|
|
Muscle hypertrophy
Time Frame: Pre- and post-intervention (16 weeks of training)
|
Muscle thickness is an indicator of muscle size and hypertrophy. It reflects the structural adaptations that occur in response to training. Ultrasound is used to measure the thickness of muscles such as the quadriceps, biceps, and triceps. Measurement Tool: Ultrasound imaging Scale: Muscle thickness in millimeters (mm) Higher scores indicate greater muscle hypertrophy. |
Pre- and post-intervention (16 weeks of training)
|
|
Cognitive Capacity
Time Frame: Pre- and post-intervention (16 weeks of training)
|
The Montreal Cognitive Assessment (MoCA) is a brief screening tool used to assess cognitive function. It evaluates multiple cognitive domains, including memory, attention, language, and executive functions. It is commonly used to assess cognitive decline or impairments. Measurement Tool: MoCA test Scale: MoCA score ranges from 0 to 30, with higher scores indicating better cognitive function. Higher scores indicate better cognitive function. |
Pre- and post-intervention (16 weeks of training)
|
Collaborators and Investigators
Publications and helpful links
General Publications
- Martinikorena I, Martinez-Ramirez A, Gomez M, Lecumberri P, Casas-Herrero A, Cadore EL, Millor N, Zambom-Ferraresi F, Idoate F, Izquierdo M. Gait Variability Related to Muscle Quality and Muscle Power Output in Frail Nonagenarian Older Adults. J Am Med Dir Assoc. 2016 Feb;17(2):162-7. doi: 10.1016/j.jamda.2015.09.015. Epub 2015 Nov 11.
- Mc Dermott EJ, Balshaw TG, Brooke-Wavell K, Maden-Wilkinson TM, Folland JP. Fast and ballistic contractions involve greater neuromuscular power production in older adults during resistance exercise. Eur J Appl Physiol. 2022 Jul;122(7):1639-1655. doi: 10.1007/s00421-022-04947-x. Epub 2022 Apr 16.
- Bandeira-Guimaraes M, Blanco-Rambo E, Vieira AF, Saez de Asteasu ML, Pinto RS, Izquierdo M, Cadore EL. Chronic Effects of Different Intensities of Power Training on Neuromuscular Parameters in Older People: A Systematic Review with Meta-analysis. Sports Med Open. 2023 Oct 24;9(1):98. doi: 10.1186/s40798-023-00646-9.
- de Vos NJ, Singh NA, Ross DA, Stavrinos TM, Orr R, Fiatarone Singh MA. Optimal load for increasing muscle power during explosive resistance training in older adults. J Gerontol A Biol Sci Med Sci. 2005 May;60(5):638-47. doi: 10.1093/gerona/60.5.638.
Helpful Links
Study record dates
Study Major Dates
Study Start (Actual)
Primary Completion (Estimated)
Study Completion (Estimated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Actual)
Study Record Updates
Last Update Posted (Actual)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Other Study ID Numbers
- 85503024.6.0000.5347
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
Studies a U.S. FDA-regulated device product
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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