AI-Assisted Rehabilitation In Frailty

September 9, 2025 updated by: Ong Chong Yau, SingHealth Community Hospitals

AI-Assisted Rehabilitation for Frail Older Adults Discharged From Community Hospitals: A Hybrid Effectiveness-Implementation Trial

This study investigates the effectiveness and implementation of an AI-assisted rehabilitation tool for adults with frailty in the real-world. The main questions it aims to answer are:

Does AI-assisted rehabilitation among frail adults improve patients' physical outcomes? Is there a particular subgroup of frail subjects that will benefit most from AI-assisted rehabilitation?

Researchers will compare AI-assisted rehabilitation to standard practice (advice and QR link for rehabilitation videos to be done at home) to see if AI-assisted rehabilitation improves clinical outcomes compared to standard practice.

Participants will either:

Undergo an AI-assisted rehab with the AI-sensor tool or a standard practice post-discharge from community hospitals for 12 weeks.

Undergo interval assessments of outcomes. Keep a diary of outpatient rehabilitations (if applicable for the subjects).

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

This is a pragmatic, randomized controlled study on frail patients discharged from three community hospitals in Singapore.

Study Type

Interventional

Enrollment (Estimated)

220

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • Adults aged ≥ 21years
  • Clinical Frailty Score (CFS) 4 to 6 *
  • Provided informed consent (for cognitively impaired persons MMSE<18, next-of-kin or proxy to give consent).
  • Have access to smartphone/tablet (own or loaned from investigators)/

Exclusion Criteria:

  • Medical conditions precluding safe home exercises or severely affect interaction with AI-tool (angina, vision loss, hearing impairment).
  • Cognitive impairment (MMSE<18) and no caregiver to assist with use of tool.
  • Participation in structured outpatient physiotherapy (>1 times/week), or day rehab programme.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Health Services Research
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Triple

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Other: Usual care
Verbal and written discharge summary, advice, and referral to outpatient physiotherapy (if applicable)
Other: usual care only
Verbal and written discharge summary, advice, and referral to outpatient physiotherapy (if applicable)
Active Comparator: AI-assisted rehabilitation
AI-assisted rehabilitation on top of usual care
Device: AI-assisted rehabilitation
Receives AI-assisted rehabilitation post-discharge at home in addition to usual care

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Absolute Functional Gain (AFG)
Time Frame: baseline, 3, 6, 9 and 12 weeks.
AFG= Functional score (at discharge/follow-up points) - functional score (at admission). Functional score is based on Modified Barthel Index (MBI).
baseline, 3, 6, 9 and 12 weeks.

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Functional outcome: Short Physical Performance Battery (SPBB)
Time Frame: baseline, 3, 6, 9, 12-weeks
SPBB is a validated and commonly used tool to evaluate physical performance particularly in older adults. It is based on three timed tasks: gait speed (over short distance of 4 metres), balance tests (side-by-side, semi-tandem, and full-tandem), and repetitive chair sit-to-stand (strength and endurance) performance.45 It is an indicator of vulnerability, is associated with readmissions, and predictive of all-cause mortality.
baseline, 3, 6, 9, 12-weeks

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

SingHealth Community Hospitals

Collaborators

Jurong Community Hospital, Singapore

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

December 1, 2025

Primary Completion (Estimated)

January 31, 2027

Study Completion (Estimated)

April 30, 2027

Study Registration Dates

First Submitted

September 9, 2025

First Submitted That Met QC Criteria

September 9, 2025

First Posted (Estimated)

September 16, 2025

Study Record Updates

Last Update Posted (Estimated)

September 16, 2025

Last Update Submitted That Met QC Criteria

September 9, 2025

Last Verified

September 1, 2025

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 2025-1300

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

In accordance to my ethical board and institutional requirements.

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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