Cervical Spine Abnormalities in Down Syndrome

November 21, 2025 updated by: EsraaAMahmoud, Sohag University

A Study of Cervical Spine Abnormalities Associated With Down Syndrome in Children at Sohag University

The study aims to determine the prevalence,clinical presentations and radiographic cervical spine abnormalities associated Down syndrome in children at sohag university hospital

Study Overview

Status

Active, not recruiting

Conditions

Study Type

Observational

Enrollment (Estimated)

50

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Sohag, Egypt
        • Sohag University Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

No

Sampling Method

Probability Sample

Study Population

Aims to study the prevalence, clinical presentationsand radiographic cervical spine abnormalities associated with Down syndrome in children at sohag university hospital

Description

Inclusion Criteria:

  • All patients attending to pediatric inpatient and outpatient clinics aged from 2y up to 18 y

Exclusion Criteria:

  • children with other clinical syndromes Children with other neurological disorders (eg. Cerebral palsy , myopathy, neuropathy

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Determine the prevalence, clinical presentations and radiographic cervical spine abnormalities associated with Down syndrome through study completion an average of 1 year .
Time Frame: Asses the perivlance of cervical spine abnormalities in patient with Down syndrome of patients aged from 2 years up to 18 years ,using measure tool atlanoaxial instability in ct neck (ADI>3ml)and other mutliple measures ex(weight,height,eg.)
Asses the perivlance of cervical spine abnormalities in patient with Down syndrome of patients aged from 2 years up to 18 years ,using measure tool atlanoaxial instability in ct neck (ADI>3ml)and other mutliple measures ex(weight,height,eg.)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sohag University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

October 23, 2025

Primary Completion (Estimated)

December 23, 2026

Study Completion (Estimated)

December 30, 2026

Study Registration Dates

First Submitted

September 22, 2025

First Submitted That Met QC Criteria

November 21, 2025

First Posted (Estimated)

December 3, 2025

Study Record Updates

Last Update Posted (Estimated)

December 3, 2025

Last Update Submitted That Met QC Criteria

November 21, 2025

Last Verified

November 1, 2025

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Soh-Med-25-7_17MS

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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