Pediatric Renal Emergencies: Presentations and Outcomes at Sohag University Hospitals

April 15, 2026 updated by: Fady Medhat Farouk, Sohag University

Variable Manifestations and Outcomes of Renal Diseases Among Children Presenting to the Emergency Room at Sohag University Hospitals

Renal diseases in children present with a wide spectrum of clinical manifestations, ranging from mild urinary abnormalities to severe acute kidney injury requiring urgent management. Early recognition in the emergency setting is essential to improve outcomes, yet data on pediatric renal emergencies in Upper Egypt remain limited.

This prospective cohort study aims to characterize the clinical presentations of renal diseases among children presenting to the emergency room at Sohag University Hospitals, determine the prevalence of specific renal conditions, and evaluate immediate management outcomes and short-term follow-up after discharge.

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Study Type

Observational

Enrollment (Estimated)

50

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult

Accepts Healthy Volunteers

N/A

Sampling Method

Non-Probability Sample

Study Population

The study population will include children aged 1 month to 18 years presenting to the emergency room of Sohag University Hospitals with clinical features suggestive of renal involvement. This includes both previously healthy children with new-onset symptoms and those with known renal diseases presenting with acute exacerbations. Patients will undergo routine clinical evaluation, laboratory investigations, and imaging as part of standard care, and will be followed during their hospital stay and after discharge.

Description

Inclusion Criteria:

  • Children aged 1 month to 18 years. Presentation to the emergency room at Sohag University Hospitals with signs and/or symptoms suggestive of renal involvement (e.g., edema, hematuria, oliguria/anuria, flank pain, hypertension).

Patients with a known history of renal disease presenting with acute exacerbation.

Written informed consent obtained from parents or legal guardians.

Exclusion Criteria:

  • Incomplete or missing essential clinical, laboratory, or imaging data. Refusal or inability to obtain written informed consent from parents or legal guardians.

Patients with suspected renal symptoms later confirmed to have non-renal causes.

Patients who received renal replacement therapy prior to presentation at another facility.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Pediatric patients with renal diseases
Other: Standard emergency room management
Participants receive routine clinical assessment, investigations, and management according to Sohag University Hospitals emergency protocols. No study-specific intervention is applied.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Frequency of Clinical Presentations and Final Diagnoses of Pediatric Renal Diseases
Time Frame: At baseline (emergency room presentation) through hospital stay (up to discharge, typically within 7 days)

Percentage (%) of patients presenting with specific clinical features (e.g., edema, hematuria, oliguria, hypertension) assessed by clinical examination and initial laboratory investigations.

Distribution (%) of final diagnoses (e.g., acute kidney injury, urinary tract infection, congenital anomalies, glomerular diseases) based on clinical evaluation, laboratory results, and imaging studies.
At baseline (emergency room presentation) through hospital stay (up to discharge, typically within 7 days)

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Sohag University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

June 5, 2026

Primary Completion (Estimated)

July 5, 2027

Study Completion (Estimated)

October 5, 2027

Study Registration Dates

First Submitted

March 29, 2026

First Submitted That Met QC Criteria

April 15, 2026

First Posted (Actual)

April 22, 2026

Study Record Updates

Last Update Posted (Actual)

April 22, 2026

Last Update Submitted That Met QC Criteria

April 15, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • Soh-med-25-7-20MS

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

YES

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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